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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of oral pathology & medicine 26 (1997), S. 0 
    ISSN: 1600-0714
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Opportunistic fungal infections account for a significant amount of morbidity associated with HIV disease. We report here a case of localised oral histoplasmosis without evidence of disseminated disease in a patient who lacked stigmata of HIV disease at the time of initial presentation. The diagnosis is based on histology with special stains, complement fixing antibodies in serum, and culture of the organism from fresh tissues. Activation of subclinical disease following an infection in Uganda may explain the development of these exophytic oral lesions in this British resident.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1824-3096
    Keywords: smoking ; diet ; exercise ; phisical activity ; skinfolds ; circumferences
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract This paper examined the ethnic differences in regional adiposity, measured as circumferences and skinfolds, after controlling for the effects of some indicators of lifestyle patterns, namely, smoking, physical activity, family history of diabetes and diet, in 262 adult White and 100 migrant Pakistani (of Kashmiri origin) males in Peterborough, East Anglia, England. Amongst individuals regularly consuming various dietary products, Pakistani men had significantly lower mean chest, minimum waist and maximum hip circumferences compared with Caucasians; they also had significantly higher mean abdomen, subscapular and suprailiac skinfolds, but significantly lower mean forearm skinfold. Ethnicity was found to have significant associations with chest (p〈0.01), waist (p〈0.025), and hip (p〈0.05) circumferences; and abdomen (p〈0.005), subscapular (p〈0.001), suprailiac (p〈0.025), midaxillary (p〈0.05) and forearm (p〈0.005) skinfolds, after removing the combined effects of smoking, physical activity and various dietary products. Results also indicated that migrant Pakistanis had significantly higher mean abdomen (+4.6 mm), subscapular (+5.3 mm), suprailiac (+4.4 mm) and midaxillary skinfolds (+3.3 mm); but significantly lower mean forearm (−1.2 mm) and medial calf (−1.2 mm) skinfolds, and chest circumference (−1.8 cm), after removing the combined effects of age, age2, smoking status, physical activity undertaken, diet and family history of diabetes. These significant ethnic differences existed even after removing the effect of body mass index (BMI). This investigation provides clear evidence that the significant ethnic difference in regional adiposity between adult Caucasians and migrant Pakistanis of Kashmiri origin was not due to the various lifestyle indicators but may be influenced by genetic determinants. Further studies are needed to determine the nature and extent of the genetic component of this ethnic heterogeneity in regional adiposity between Caucasians and migrant Pakistanis.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1546-1718
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] Analysis of patients with inherited hypokalaemic alkalosis resulting from salt–wasting has proved fertile ground for identification of essential elements of renal salt homeostasis and blood–pressure regulation. We now demonstrate linkage of this phenotype to a segment of chromosome 1 ...
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1432-198X
    Keywords: Key words: Haemolytic uraemic syndrome ; Glomerular thrombosis ; Arteriolar thromboses ; Neutrophils
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract.  Autopsy material was examined from British children dying early in the course of haemolytic uraemic syndrome (HUS). These presented after 1983, the period in which verocytotoxin-producing Escherichia coli (VTEC) infection was confirmed as the leading cause of diarrhoea-associated (D+HUS) in the United Kingdom. Of 18 cases referred for this study, 3 were found on review to have no history of a diarrhoeal prodrome (D-HUS). In the D+ patients, the median duration from onset of diarrhoea to death was 8 days (range 4–42 days). VTEC infection was confirmed in 6 cases. All had neutrophilia at presentation (median 21, range 15–49.8 × 109/l). The 15 cases had uniform pathological features, consisting of glomerular thromboses and congested rather than ischaemic glomeruli. Arteriolar thromboses were common at the hilum of glomeruli and were sometimes also seen proximally, including in interlobular arteries. There were cortical infarcts in 5 cases with extensive thrombosis. Cases were demonstrated to have significantly greater numbers of neutrophils expressed per 100 glomeruli than controls, when counted using immunohistological stains to neutrophil elastase and CD15. This study showed uniformity of the renal changes in D+ HUS and gave further evidence of the importance of neutrophils in the pathogenesis of the disease.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Journal of clinical psychology in medical settings 4 (1997), S. 417-435 
    ISSN: 1573-3572
    Keywords: marriage ; coronary heart disease ; myocardial infarction ; social support
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The purpose of this study was to examine the relationship of marital status to health outcomes in 818 post-MI, coronary artery bypass surgery, and angioplasty patients (651 males, 157 females) from seven Northern California hospitals who completed 12 months of a nurse-managed, home-based multifactorial risk reduction program. Compared to married patients, nonmarried patients were significantly less likely to complete the program than married patients, more likely to smoke at baseline, and drank significantly less alcohol at baseline. At 12 months there were no significant differences between married and nonmarried groups on smoking cessation rates, HDL, LDL, triglycerides, or exercise treadmill test results. When patients were categorized as married, divorced, separated, widowed, or single, similar results were found for the analyses using two groups (married versus nonmarried), with the following exceptions. Separated patients were significantly less likely to quit smoking. In addition, separated patients showed significantly higher rates of starting (and continuing) to smoke during the time following their MI. Mortality was not significantly different between married and unmarried patients. Implications for intervention with separated patients and the importance of assessing both marital status and marital quality are discussed.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 25 (1997), S. 931-952 
    ISSN: 0271-2091
    Keywords: finite element method ; free surface ; updated Lagrangian-Eulerian ; Engineering ; Numerical Methods and Modeling
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: An updated free surface Lagrangian-Eulerian finite element kinematic description is used to simulate free surface flow problems associated with mould filling. The method proposed results in an accurate determination of the front, making it ideal for problems in which free surface boundary conditions play an important role. Significant saving in CPU time can be obtained over other fixed mesh approaches by virtue of the air domain being ignored. Assuming a laminar regime for the flow field, a mixed interpolation formulation is used to approximate the discretized governing equations for elimination.   Of particular interest is the method implementation to restrict the number of remeshing operations and track the moving free surface within an arbitrary domain, either with or without internal obstacles. The method used to automatically assign boundary conditions to the changing domain is described. A dam break problem is modelled numerically and compared against experimentally derived data in order to validate the model. A further numerical example demonstrates the capabilities of the algorithm developed to model the filling of an industrial casting. © 1997 John Wiley & Sons, Ltd.
    Additional Material: 23 Ill.
    Type of Medium: Electronic Resource
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