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Development of a new disease-specific quality-of-life questionnaire to adults living with haemophilia (2004)

Arranz, P. ; Remor, E. ; Quintana, M. ; [et al.]

Oxford, UK : Blackwell Science Ltd

Haemophilia 10 (2004), S. 0

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ISSN: 1365-2516

Source: Blackwell Publishing Journal Backfiles 1879-2005

Topics: Medicine

Notes: Summary. A haemophilia-specific health-related quality-of-life questionnaire (named ‘Hemofilia-QoL’) was developed to assess quality-of-life in adults with haemophilia, and was psychometrically tested. Seventy-three interviews with haemophilia patients and health care professionals were used to generate the items included in the questionnaire, and expert ratings on the items formulated were used to screen them for potential omission. This was followed by psychometric testing in a sample of 35 patients. Preliminary psychometric testing of the revised questionnaire version, which contains 10 domains (physical health, physical role, joint damage, pain, treatment satisfaction, emotional role, mental health, social support), showed acceptable reliability (α = 0.94 for the Hemofilia-QoL total score) and validity, and this will be examined in a subsequent study with a larger patient sample.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1111/j.1365-2516.2004.00918.x

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Amorphous to polycrystalline transition in Co $\mathsf{_x}$ Si $\mathsf{_{1-x}}$ alloy thin films (2004)

Vélez, M. ; Mény, C. ; Valvidares, S. M. ; [et al.]

Springer

The European physical journal 41 (2004), S. 517-524

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ISSN: 1434-6036

Source: Springer Online Journal Archives 1860-2000

Topics: Physics

Notes: Abstract. The transition from amorphous to polycrystalline microstructure has been studied in sputtered Co x Si1-x alloy films by structural, magneto-optical and Nuclear Magnetic Resonance measurements. For $x \geq 0.76$ , Si is diluted into Co without significantly altering the polycrystalline microstructure, composed of a mixture of hcp and fcc grains. However, the fraction of Co atoms that contribute to the Nuclear Magnetic Resonance signal is found to decrease steeply (down to about 60 $\%$ at x = 0.76) suggesting a microscopic segregation of a Si rich phase that induces a large degree of disorder. This is reflected in a harder magnetic behavior and a strong anisotropy dispersion. Below x = 0.75, the transition to an amorphous microstructure results in a sudden increase in the fraction of Co atoms within a ferromagnetic phase, indicating the recovery of the microscopic homogeneity. Also a significant enhancement of the macroscopic magnetic anisotropy is found for amorphous films with compositions right below the transition. Within the amorphous phase a second regime of Si segregation appears characterized by a constant Co local environment and constant magnetic properties. Finally, for x = 0.65 there is a significant Si enrichment in the Co environment and the films become non magnetic for compositions below this point.