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  • 2000-2004  (36)
  • 2004  (36)
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  • 2000-2004  (36)
Year
  • 1
    Electronic Resource
    Electronic Resource
    The Applicant Attribution-Reaction Theory (AART): An Integrative Theory of Applicant Attributional Processing (2004)
    Oxford, UK and Boston, USA : Blackwell Publishing Ltd
    International journal of selection and assessment 12 (2004), S. 0 
    Details
    ISSN: 1468-2389
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Economics
    Notes: This article proposes a new theory called the Applicant Attribution-Reaction Theory (AART) to better understand attributional processes in the formation of applicant reactions. The theory proposes that applicants' affective, behavioral, and cognitive reactions, such as fairness, test perceptions, test performance, and motivation, are fundamentally driven by an attributional process. A key implication of the theory is that perceptions such as fairness and test attitudes carry little explanatory power; instead they are consequences of attributional processing. We provide a brief review of dominant applicant reactions frameworks, review the social psychological literature on attributions, and present the theory. We then contrast the theory to existing conceptualizations, and finally describe its potential for better understanding several key topics in applicant reactions, including the justice judgment process, test performance, and racial subgroup differences. The theory has the potential to integrate many diverse perspectives on applicant reactions, and provides numerous directions for future research and practice.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.0965-075X.2004.00266.x
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  • 2
    Electronic Resource
    Electronic Resource
    CEP11004, a novel inhibitor of the mixed lineage kinases, suppresses apoptotic death in dopamine neurons of the substantia nigra induced by 6-hydroxydopamine (2004)
    Oxford, UK : Blackwell Science Ltd
    Journal of neurochemistry 88 (2004), S. 0 
    Details
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: There is much evidence that the kinase cascade which leads to the phosphorylation of c-jun plays an important signaling role in the mediation of programmed cell death. We have previously shown that c-jun is phosphorylated in a model of induced apoptotic death in dopamine neurons of the substantia nigra in vivo. To determine the generality and functional significance of this response, we have examined c-jun phosphorylation and the effect on cell death of a novel mixed lineage kinase inhibitor, CEP11004, in the 6-hydroxydopamine model of induced apoptotic death in dopamine neurons. We found that expression of total c-jun and Ser73-phosphorylated c-jun is increased in this model and both colocalize with apoptotic morphology. CEP11004 suppresses apoptotic death to levels of 44 and 58% of control values at doses of 1.0 and 3.0 mg/kg, respectively. It also suppresses, to approximately equal levels, the number of profiles positive for the activated form of capase 9. CEP11004 markedly suppresses striatal dopaminergic fiber loss in these models, to only 22% of control levels. We conclude that c-jun phosphorylation is a general feature of apoptosis in living dopamine neurons and that the mixed lineage kinases play a functional role as up-stream mediators of cell death in these neurons.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1471-4159.2003.02176.x
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Robin Moore's Unfinished Masterpiece (2004)
    Oxford, UK : Blackwell Publishing
    The @journal of popular culture 37 (2004), S. 0 
    Details
    ISSN: 1540-5931
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Ethnic Sciences
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.0022-3840.2004.00077.x
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  • 4
    Electronic Resource
    Electronic Resource
    DISCUSSION (2004)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of the American Water Resources Association 40 (2004), S. 0 
    Details
    ISSN: 1752-1688
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Architecture, Civil Engineering, Surveying , Geography
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1752-1688.2004.tb01070.x
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  • 5
    Electronic Resource
    Electronic Resource
    THE MEDIAL TEMPORAL LOBE* (2004)
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Neuroscience 27 (2004), S. 279-306 
    Details
    ISSN: 0147-006X
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Biology , Medicine
    Notes: The medial temporal lobe includes a system of anatomically related structures that are essential for declarative memory (conscious memory for facts and events). The system consists of the hippocampal region (CA fields, dentate gyrus, and subicular complex) and the adjacent perirhinal, entorhinal, and parahippocampal cortices. Here, we review findings from humans, monkeys, and rodents that illuminate the function of these structures. Our analysis draws on studies of human memory impairment and animal models of memory impairment, as well as neurophysiological and neuroimaging data, to show that this system (a) is principally concerned with memory, (b) operates with neocortex to establish and maintain long-term memory, and (c) ultimately, through a process of consolidation, becomes independent of long-term memory, though questions remain about the role of perirhinal and parahippocampal cortices in this process and about spatial memory in rodents. Data from neurophysiology, neuroimaging, and neuroanatomy point to a division of labor within the medial temporal lobe. However, the available data do not support simple dichotomies between the functions of the hippocampus and the adjacent medial temporal cortex, such as associative versus nonassociative memory, episodic versus semantic memory, and recollection versus familiarity.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1146/annurev.neuro.27.070203.144130
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  • 6
    Electronic Resource
    Electronic Resource
    GMOs: Prospects for Productivity Increases in Developing Countries (2004)
    Lincoln, Neb. : Berkeley Electronic Press (now: De Gruyter)
    Journal of agricultural & food industrial organization 2.2004, 2, art2 
    Details
    ISSN: 1542-0485
    Source: Berkeley Electronic Press Academic Journals
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Economics
    Notes: There are two mechanisms by which modern genetically modified organism (GMO) products can affect productivity in developing countries. The first is the 'Genes for Rent' mechanism where a recipient country agrees with a GMO company to incorporate a GMO product (e.g., a Bt gene in cotton varieties) and pay a technology fee. The second is the 'Transgenic Breeding' mechanism in which National Agricultural Research System (NARS) breeders use modern biotech methods marker-aided breeding, genetic maps, and genomics research to produce GMO traits of economic value in crop varieties. The first mechanism requires little skill on the part of the recipient country (the GMO supplier will incorporate the gene into a number of varieties). But these GMO products are of little value in "traditional" crop varieties. Few countries have the Intellectual Property Rights or regulatory regimes at present to support this mechanism. The second mechanism is very demanding of skills by NARS breeders. Only a few NARS programs (notably China, India, Brazil, Argentina, and a few other countries) are investing in these skills. The promise of GMO-based productivity gains in developing countries is thus constrained. Only a few countries are positioned to pursue both mechanisms.
    Type of Medium: Electronic Resource
    URL: http://www.bepress.com/jafio/vol2/iss2/art2
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    Paper (German National Licenses)
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  • 7
    Electronic Resource
    Electronic Resource
    ZINC AND THE RISK FOR INFECTIOUS DISEASE (2004)
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Nutrition 24 (2004), S. 255-275 
    Details
    ISSN: 0199-9885
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Zinc is an essential micronutrient for human growth, development, and immune function. Zinc deficiency impairs overall immune function and resistance to infection. Mild to moderate zinc deficiency can be best detected through a positive response to supplementation trials. Zinc supplementation has been shown to have a positive effect on the incidence of diarrhea (18% reduction, 95% CI: 7-28%) and pneumonia (41% reduction, 95% CI: 17-59%), and might lead to a decrease in the incidence of malaria. Zinc has also proven to decrease the duration of diarrhea by 15% (95% CI: 5-24%). Maternal zinc supplementation may lead to a decrease in infant infections. Studies assessing the role of zinc supplementation among persons with HIV, tuberculosis, and the common cold have not been conclusive. Two studies have shown zinc supplementation to decrease child mortality by more than 50%. Zinc clearly has an important role in infant and childhood infectious diseases; programs to increase the intake of zinc among deficient populations are needed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1146/annurev.nutr.23.011702.073054
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    Paper (German National Licenses)
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  • 8
    Electronic Resource
    Electronic Resource
    Lack of α-synuclein does not alter apoptosis of neonatal catecholaminergic neurons (2004)
    Oxford, UK : Blackwell Science Ltd
    European journal of neuroscience 20 (2004), S. 0 
    Details
    ISSN: 1460-9568
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: α-Synuclein is an abundant neuronal protein of uncertain function linked to Parkinson's disease. Numerous studies have proposed an antiapoptotic function for α-synuclein, based on overexpression experiments in cell lines. To explore whether α-synuclein has such a physiological function, we assessed the response of wild type or α-synuclein null neonatal mouse sympathetic neurons to nerve growth factor deprivation, a well-characterized stimulus of neuronal apoptosis. There was no difference in the rate of neuronal loss, neuronal apoptosis, or c-jun phosphorylation. Furthermore, the absence of α-synuclein did not alter the magnitude of naturally occurring cell death in vivo in substantia nigra pars compacta. Therefore, α-synuclein is unlikely to play a significant role in apoptotic signalling in catecholaminergic neurons of the neonatal nervous system.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1460-9568.2004.03638.x
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  • 9
    Electronic Resource
    Electronic Resource
    The importance of environmental modifiers of the relationship between substance use and harm (2004)
    Oxford, UK : Blackwell Science Ltd
    Addiction 99 (2004), S. 0 
    Details
    ISSN: 1360-0443
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine , Psychology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1360-0443.2004.00719.x
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    Paper (German National Licenses)
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  • 10
    Electronic Resource
    Electronic Resource
    Medial prefrontal cortical integration of psychological stress in rats (2004)
    Oxford, UK : Blackwell Science Ltd
    European journal of neuroscience 20 (2004), S. 0 
    Details
    ISSN: 1460-9568
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The present study aimed to determine whether the medial prefrontal cortex (mPFC) (prelimbic and infralimbic regions) is implicated in the integration of a stress response. Sprague-Dawely rats were implanted with telemetry probes and guide cannulae so that either muscimol or vehicle could be administered locally within the mPFC or dorsomedial hypothalamus (DMH). The heart rate and blood pressure of rats was continuously recorded as either muscimol or vehicle was administered centrally and rats were either exposed to restraint stress or left alone in their home cages. After the stress challenge, or equivalent period, rats that had received intra-mPFC injections were processed for immunohistochemical detection of Fos throughout the neuraxis. Bilateral microinjection of muscimol into the mPFC had no effect upon either baseline cardiovascular parameters or restraint stress-induced tachycardia or pressor responses whereas, in the DMH, pretreatment with muscimol attenuated the cardiovascular stress response. Analysis of Fos expression throughout the CNS of nonstressed rats showed no effect of muscimol injections into the mPFC on baseline expression in the nuclei examined. In contrast, rats that had received muscimol injections into their mPFC and were subsequently restrained exhibited an increase in the number of Fos-positive cells in the DMH, medial amygdala, and medial nucleus tractus solitarius as compared to vehicle-injected rats that experienced restraint stress. These results indicate that, during acute psychological stress, the mPFC does not modulate the cardiovascular system in rats but does inhibit specific subcortical nuclei to exert control over aspects of an integrated response to a stressor.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1460-9568.2004.03707.x
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