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1

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3′,5′-Cyclic Guanosine Monophosphate Activates Mitogen-Activated Protein Kinase in Rat Pinealocytes (1999)

Ho, A. K. ; Hashimoto, K. ; Chik, C. L.

Oxford UK : Blackwell Science Ltd.

Journal of neurochemistry 73 (1999), S. 0

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ISSN: 1471-4159

Source: Blackwell Publishing Journal Backfiles 1879-2005

Topics: Medicine

Notes: Abstract : The role of 3′,5′-cyclic guanosine monophosphate (cGMP) in the activation of mitogen-activated protein kinases (MAPKs) was investigated in rat pinealocytes. Treatment with dibutyryl cGMP (DBcGMP) dosedependently increased the phosphorylation of both p44 and p42 isoforms of MAPK. This effect of DBcGMP was abolished by PD98059 (a MAPK kinase inhibitor), H7 (a nonspecific protein kinase inhibitor), and KT5823 [a selective cGMP-dependent protein kinase (PKG) inhibitor]. Elevation of cellular cGMP content by treatment with norepinephrine, zaprinast (a cGMP phosphodiesterase inhibitor), or nitroprusside was effective in activating MAPK. Natriuretic peptides that were effective in elevating cGMP levels in this tissue were also effective in activating MAPK. Our results indicate that, in this neuroendocrine tissue, the cGMP/PKG signaling pathway is an important mechanism used by hormones and neurotransmitters in activating MAPK.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1046/j.1471-4159.1999.0730598.x

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2

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Multiple warty dyskeratomas of the scalp (1997)

GRIFFITHS, T.W. ; HASHIMOTO, K. ; SHARATA, H.H. ; [et al.]

Oxford, UK : Blackwell Publishing Ltd

Clinical and experimental dermatology 22 (1997), S. 0

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ISSN: 1365-2230

Source: Blackwell Publishing Journal Backfiles 1879-2005

Topics: Medicine

Notes: Two patients presented with the unusual condition of multiple warty dyskeratomas on the scalp. Biopsies of affected skin stained positive with human keratin monoclonal antibodies HKN-6 and -7, specific for cortex and inner root sheath of normal human hair, respectively. Multiple warty dyskeratomas are a rare occurrence and their actiopathogenesis remains elusive. Positive immunohistochemical staining of a lesion with antikeratin antibodies HKN-6 and -7, specific for human hair keratin, suggests a follicular origin for warty dyskeratoma.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1111/j.1365-2230.1997.tb01059.x

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3

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Massive cutaneous mucinosis associated with systemic lupus erythematosus (1997)

MARUYAMA, M. ; MIYAUCHI, S. ; HASHIMOTO, K.

Oxford, UK : Blackwell Publishing Ltd

British journal of dermatology 137 (1997), S. 0

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ISSN: 1365-2133

Source: Blackwell Publishing Journal Backfiles 1879-2005

Topics: Medicine

Notes: We describe a 23-year-old Japanese man with systemic lupus erythematosus (SLE) who developed massive cutaneous mucinosis. He was diagnosed with SLE when he was 11 years old. Prednisolone therapy (30 mg/day) was initiated and reduced to 10 mg/day 3 months later: the SLE had been well-controlled with this dose of prednisolone for 12 years. However, infiltrated erythematous plaques developed on the middle-lateral area of his back at 17 years old and progressed to erythematous and elastic soft tumorous masses over 20 cm in diameter at 23 years old. Biopsies of the lesions on the nape revealed massive mucin deposition. Topical injection with hyaluronidase decreased the lesion. This cutaneous mucinosis can be distinguished clinically and histopathologically from papular and nodular mucinosis associated with SLE. The present case might be an unusual clinical variant of cutaneous mucinosis associated with SLE.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1046/j.1365-2133.1997.18681937.x

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4

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Primary low cerebrospinal fluid pressure syndrome with galactorrhea: findings at MR imaging (1996)

Sawada, A ; Morita, N ; Yoshida, S ; [et al.]

USA/Oxford, UK : Blackwell Science Ltd

Cephalalgia 16 (1996), S. 0

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ISSN: 1468-2982

Source: Blackwell Publishing Journal Backfiles 1879-2005

Topics: Medicine

Notes: A case of primary low cerebrospinal fluid (CSF) pressure syndrome with galactorrhea is reported. Magnetic resonance imaging demonstrated diffusely enhanced meninges, edematous brain, and enlarged pituitary gland. Coincidental enlargement of pituitary gland and edematous brain due to low CSF pressure compressed the pituitary portal system. The 1ow-perfused anterior lobe of pituitary gland would be the mechanism of galactorrhea.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1046/j.1468-2982.1996.1602124.x

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Transmission electron microscopy observation of interfacial reactions in high-temperature sputtered Al alloy/TiN system (1995)

Okihara, M. ; Hirashita, N. ; Hashimoto, K. ; [et al.]

Woodbury, NY : American Institute of Physics (AIP)

Applied Physics Letters 66 (1995), S. 1328-1330

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ISSN: 1077-3118

Source: AIP Digital Archive

Topics: Physics

Notes: Transmission electron microscopy was used to study the interfacial reactions and crystallographic structure in high-temperature sputtered Al alloy/TiN system. An intermediate layer and semispherical precipitates were observed as the reaction products during high-temperature sputtering at 500 °C. Electron diffraction analysis indicated that the intermediate layer consisted of hexagonal AlN and cubic TiN. Semispherical precipitates were also found to consist of tetragonal Al3Ti. Additional energy dispersive x-ray spectrometer analysis suggested that the intermediate layer was formed by the diffusion of Al atoms into the TiN film. © 1995 American Institute of Physics.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1063/1.113231

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6

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Two types of spiral growth of C60 films on KBr(001) (1997)

Kim, Y. ; Jiang, L. ; Iyoda, T. ; [et al.]

Woodbury, NY : American Institute of Physics (AIP)

Applied Physics Letters 71 (1997), S. 3489-3491

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ISSN: 1077-3118

Source: AIP Digital Archive

Topics: Physics

Notes: Two types of spiral growth, single and double spirals, of C60 epitaxial films on a KBr(001) substrate were observed by atomic force microscopy (AFM). These single and double spirals were found on films grown at different rates. All spiral islands show the threefold symmetry of the face-centered-cubic (fcc) structure. In the case of single spirals, many fringes were observed in three equivalent [11¯0] directions on the fcc (111) surface. From the AFM images, we concluded that the growth process of these spirals can be explained by the classical crystal growth theory of Burton, Cabrera, and Frank and that screw dislocations form without any direct influence of the substrate. © 1997 American Institute of Physics.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1063/1.120368

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7

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Selective In-Plane Photoelectrochemical Reaction of an Azobenzene Derivative in an Assembled Film (1995)

Wang, R. ; Iyoda, T. ; Hashimoto, K. ; [et al.]

s.l. : American Chemical Society

The @journal of physical chemistry 〈Washington, DC〉 99 (1995), S. 3352-3356

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Source: ACS Legacy Archives

Topics: Chemistry and Pharmacology , Physics

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1021/j100010a053

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8

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Resonance-enhanced multiphoton electron detachment spectrum of C5− (1995)

Ohara, M. ; Shiromaru, H. ; Achiba, Y. ; [et al.]

College Park, Md. : American Institute of Physics (AIP)

The Journal of Chemical Physics 103 (1995), S. 10393-10394

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ISSN: 1089-7690

Source: AIP Digital Archive

Topics: Physics , Chemistry and Pharmacology

Notes: The resonance-enhanced multiphoton electron detachment spectrum of C5− was measured. The peaks observed at 470–500 nm were assigned to be 1 photon excitation of 2Πu to the 2Πg state. The vibrational structure gives the symmetric stretching frequency of ν2=718±43 cm−1 for the excited state of C5−. © 1995 American Institute of Physics.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1063/1.469876

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9

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Study of the Photochromic Properties of Amorphous MoO3 Films Using Raman Microscopy (1995)

Ajito, K. ; Nagahara, L. A. ; Tryk, D. A. ; [et al.]

s.l. : American Chemical Society

The @journal of physical chemistry 〈Washington, DC〉 99 (1995), S. 16383-16388

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Source: ACS Legacy Archives

Topics: Chemistry and Pharmacology , Physics

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1021/j100044a028

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10

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Reactions of Singly Charged Alkaline-Earth Metal Ions with Water Clusters: Characteristic Size Distribution of Product Ions (1995)

Sanekata, M. ; Misaizu, F. ; Fuke, K. ; [et al.]

s.l. : American Chemical Society

Journal of the American Chemical Society 117 (1995), S. 747-754

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ISSN: 1520-5126

Source: ACS Legacy Archives

Topics: Chemistry and Pharmacology

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1021/ja00107a018

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