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  • 2005-2009  (213)
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Material
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Year
  • 1
    Electronic Resource
    Electronic Resource
    Is photoinhibition of zooxanthellae photosynthesis the primary cause of thermal bleaching in corals? (2005)
    Oxford, UK : Blackwell Science Ltd
    Global change biology 11 (2005), S. 0 
    Details
    ISSN: 1365-2486
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Energy, Environment Protection, Nuclear Power Engineering , Geography
    Notes: The bleaching of corals in response to increases in temperature has resulted in significant coral reef degradation in many tropical marine ecosystems. This bleaching has frequently been attributed to photoinhibition of photosynthetic electron transport and the consequent photodamage to photosystem II (PSII) and the production of damaging reactive oxygen species (ROS) in the zooxanthellae (Symbiodinium spp.). However, these events may be because of perturbations of other processes occurring within the zooxanthellae or the host cells, and consequently constitute only secondary responses to temperature increase. The processes involved with the onset of photoinhibition of electron transport, photodamage to PSII and pigment bleaching in coral zooxanthellae are reviewed. Consideration is given to how increases in temperature might lead to perturbations of metabolic processes in the zooxanthellae and/or their host cells, which could trigger events leading to bleaching. It is concluded that production of ROS by the thylakoid photosynthetic apparatus in the zooxanthellae plays a major role in the onset of bleaching resulting from photoinhibition of photosynthesis, although it is not clear which particular ROS are involved. It is suggested that hydrogen peroxide generated in the zooxanthellae may have a signalling role in triggering the mechanisms that result in expulsion of zooxanthellae from corals.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1529-8817.2003.00895.x
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  • 2
    Electronic Resource
    Electronic Resource
    Large-scale sequencing of human influenza reveals the dynamic nature of viral genome evolution (2005)
    [s.l.] : Nature Publishing Group
    Nature 437 (2005), S. 1162-1166 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Influenza viruses are remarkably adept at surviving in the human population over a long timescale. The human influenza A virus continues to thrive even among populations with widespread access to vaccines, and continues to be a major cause of morbidity and mortality. The virus mutates from year ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nature04239
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Talented suppliers? Strategic change and innovation in the UK aerospace industry (2005)
    Oxford, UK : Blackwell Publishing
    R & D management 35 (2005), S. 0 
    Details
    ISSN: 1467-9310
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Economics
    Notes: The 1990s marked the start of extensive re-structuring in the aerospace industry throughout the world. While the ensuing consolidation among prime contractors has been widely researched, the changes affecting the aerospace supplier base have received less attention. This exploratory study focuses on the supplier base and points to extensive re-structuring. Unlike many earlier studies, the lean supply model was found to be a rather powerful influence, with suppliers moving away from subcontractor status and taking on the mantle of ‘talented’ suppliers. However, the bolder predictions of lean supply, in terms of the dynamics of innovation, were less apparent, although there were signs that some suppliers, who genuinely warranted the title ‘talented’, were engaging in valuable process innovations.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1467-9310.2005.00370.x
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  • 4
    Electronic Resource
    Electronic Resource
    Psychological Treatment and Medication for the Mood and Anxiety Disorders: Moderators, Mediators, and Domains of Outcome (2005)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical psychology 12 (2005), S. 0 
    Details
    ISSN: 1468-2850
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Psychology
    Notes: Studies that combine pharmacotherapy with psychological treatment for the mood and anxiety disorders must consider the role of moderators (pretreatment variables that specify the conditions under which treatments are effective) and mediators (change mechanisms in the causal pathways between treatments and outcomes) in explaining the impact of experimental treatments. This article gives examples of the kinds of moderators and mediators—both psychosocial and biological—that are important to examine in combination treatment studies. It conceptualizes outcome as involving multiple domains, including mood and anxiety symptoms, life functioning, and illness costs. Research should also examine the appropriate sequencing of pharmacological and psycho-social interventions and how this sequencing may vary from disorder to disorder.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1093/clipsy.bpi012
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Author's Reply (2005)
    Oxford, UK and Malden, USA : Blackwell Science Ltd
    BJOG 112 (2005), S. 0 
    Details
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-0528.2005.00418.x
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  • 6
    Electronic Resource
    Electronic Resource
    Transcriptional profiling of spinal cord injury-induced central neuropathic pain (2005)
    Oxford, UK : Blackwell Science Ltd
    Journal of neurochemistry 95 (2005), S. 0 
    Details
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Central neuropathic pain (CNP) is an important problem following spinal cord injury (SCI), because it severely affects the quality of life of SCI patients. As in the patient population, the majority of rats develop significant allodynia (CNP rats) after moderate SCI. However, about 10% of SCI rats do not develop allodynia, or develop significantly less allodynia than CNP rats (non-CNP rats). To identify transcriptional changes underlying CNP development after SCI, we used Affymetrix DNA microarrays and RNAs extracted from the spinal cords of CNP and non-CNP rats. DNA microarry analysis showed significantly increased expression of a number of genes associated with inflammation and astrocytic activation in the spinal cords of rats that developed CNP. For example, mRNA levels of glial fibrilary acidic protein (GFAP) and Aquaporin 4 (AQP4) significantly increased in CNP rats. We also found that GFAP, S100β and AQP4 protein elevation persisted for at least 9 months throughout contused spinal cords, consistent with the chronic nature of CNP. Thus, we hypothesize that CNP development results, in part, from dysfunctional, chronically “over-activated” astrocytes. Although, it has been shown that activated astrocytes are associated with peripheral neuropathic pain, this has not previously been demonstrated in CNP after SCI.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-4159.2005.03462.x
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  • 7
    Electronic Resource
    Electronic Resource
    The Elasticity of Marginal Utility of Consumption: Estimates for 20 OECD Countries (2005)
    Oxford, UK : Blackwell Science Ltd
    Fiscal studies 26 (2005), S. 0 
    Details
    ISSN: 1475-5890
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Economics
    Notes: In social project appraisal, the policy profile of both distributional welfare weights and the social discount rate has risen considerably in recent years. This fact has important implications for the allocation of funds to social projects and policies in countries, and in unions of countries such as the EU. A key component in the formulae for both welfare weights and the social discount rate is the elasticity of marginal utility of consumption, e. A critical review of existing evidence on e suggests that the UK Treasury's preferred value of unity is too low. New evidence presented in this paper, based on the structure of personal income tax rates, suggests that, on average, for developed countries e is close to 1.4. This particular approach to the estimation of e has previously been under-utilised by researchers.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1475-5890.2005.00010.x
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  • 8
    Electronic Resource
    Electronic Resource
    Does regular cervical screening protect women from microinvasive squamous cell carcinoma of the cervix? A retrospective case–control study (2005)
    Oxford, UK and Malden, USA : Blackwell Science Ltd
    BJOG 112 (2005), S. 0 
    Details
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Objectives  To compare the smear histories of women with microinvasive squamous cell carcinoma (SCC) of the cervix to those of women with cervical intraepithelial neoplasia grade 3 (CIN3).Design  Retrospective case–control study.Setting  A large public hospital gynaecology unit.Sample  Twenty-nine consecutive women with microinvasive SCC FIGO stage 1A1 (cases). Fifty-five age-matched controls with histologically confirmed CIN3 (controls).Methods  The cases and controls were selected from institutional databases; smear histories and other information was retrieved from hospital notes or following consent from other records.Main outcome measures  The time from index smear to prior screening smear and participation in the National Screening Programme (NCSP).Results  Only 35% of cases compared with 78% controls had a smear in the last 3 years (P= 0.00008.) Cases had a longer median interval between the abnormal smear that resulted in diagnosis and the previous screening smear (4 years) compared with controls (2 years). Cases were less likely to be enrolled in the NCSP (65%) prior to their index smear than controls (85%).Conclusion  Delayed interval screening was more frequent in women with 1A1 SCC than CIN3.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-0528.2005.00537.x
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  • 9
    Electronic Resource
    Electronic Resource
    Effect of External Lubricant on Mechanical Properties of Dry-Pressed Green Bodies (2005)
    Oxford, UK : Blackwell Science Inc
    Journal of the American Ceramic Society 88 (2005), S. 0 
    Details
    ISSN: 1551-2916
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Tensile strength and fracture toughness of uniaxially compacted spray-dried ferrite powders, with and without external lubricant were measured. The addition of external lubricant significantly increased the fracture strength and decreased the strength variability. The external lubricant also led to an increase in fracture toughness and a decrease in the critical flaw size. Scanning electron microscopy examination of fracture surfaces showed an increase in the amount of transgranular fracture for the pellets compacted from the externally lubricated powder. It was concluded that the external lubricant strengthened the bonds between the spray-dried granules, thereby increasing the fracture toughness and reducing the critical flaw size. X-ray tomography of pellets showed that there was no appreciable difference in density gradients between the samples.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1551-2916.2005.00258.x
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  • 10
    Electronic Resource
    Electronic Resource
    Densification and Sintering Viscosity of Low-Temperature Co-Fired Ceramics (2005)
    Oxford, UK : Blackwell Science Inc
    Journal of the American Ceramic Society 88 (2005), S. 0 
    Details
    ISSN: 1551-2916
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: In this paper, we present sintering and uniaxial viscosity data of three commercial low-temperature co-sintered ceramic systems, i.e., DuPont 951Tape (DU), Heraeus CT2000 (CT), and Ferro A6M (FE), measured by cyclic loading dilatometry. The viscosity initially decreases with temperature, changes little during the intermediate stage, and increases towards the end of densification. The viscosity increases sharply beyond the onset of crystallization. At slower heating rates, the viscosity increases at lower temperature, because of densification and crystallization. The isothermal viscosity data range from 0.1 to 100 GPa·s between 73% and 95% density. Ceramic particle-filled glasses show a higher isothermal viscosity compared with pure glass system, i.e., FE. From master viscosity curves based on isothermal data, the activation energies for viscous flow were ∼375±30 and 450±10 kJ/mol for DU and FE, respectively. These energies are comparable to values obtained from the master sintering curve approach.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1551-2916.2005.00497.x
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