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  • 2005-2009  (4)
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  • 1
    Electronic Resource
    Electronic Resource
    Transformation and Precipitation Behavior in the New Conceptual TMCP Process Utilizing Heat Treatment On-Line Process (2007)
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 539-543 (Mar. 2007), p. 4732-4737 
    Details
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: New conceptual TMCP process for manufacturing high strength steel plates, which isapplied an on-line heat treatment immediately after accelerated cooling (ACC), was developed.Transformation and precipitation behavior in the new TMCP process was investigated andcompared with those in conventional ACC process and quenching and tempering process (Q+T).In the ACC process and Q+T process, microstructures were consisted of bainitic ferrite andsecond phase, such as cementite or martensite-austenite constituent (MA). And fine carbides, whichwere formed randomly, were observed in Q+T steel. On the other hand, in the new TMCP processpolygonal ferrite was observed in addition to bainitic ferrite and cementite, and two kinds ofprecipitation forms, random precipitation and row precipitation, were observed. It was found thatferrite transformation is promoted during heating after accelerated cooling, which brings rowprecipitation of fine carbides.Furthermore, Control of the formation of MA this new TMCP process. In the conventionalACC process, MA constituents are formed from carbon enriched untransformed austenite during aircooling after ACC, and formation of MA is hard to prevent for higher strength steels. On the otherhand, carbon enrichment to untransformed austenite can be prevented by carbide formation duringon-line heat treatment after ACC. It was demonstrated that homogeneous microstructure with verylow amount of MA constituents was achieved by the new TMCP process. And, absence of brittlephase brought excellent resistance to hydrogen induced cracking in NACE sour environment.In this paper, details of the metallurgical and mechanical feature of this new TMCP steel werediscussed, and application to sour resistant linepipe steel was introduced
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/02/15/transtech_doi~10.4028%252Fwww.scientific.net%252FMSF.539-543.4732.pdf
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Effect of Austenite as a Harder Second Phase on Ferrite Substructure Evolution by Intercritical Rolling (2007)
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 558-559 (Oct. 2007), p. 607-610 
    Details
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Effect of austenite as a harder second phase on ferrite substructure evolution by intercriticalrolling has been investigated using 0.12C-0.3Si-1.35Mn steel. Slab was reheated at 780°C (ferrite; α +austenite; γ phase region) and rolled with 90% reduction down to 12mm in thickness using laboratorymill. 700°C (ferrite; α + cementite; θ phase region) rolled plate was also prepared to compare with 780°Crolled plate. Microstructure distribution along the plate thickness has been observed in detail by SEMand EBSD. Microstructure showed mixed structure of fine-grained ferrite and elongated ferrite for bothof the plates. The ratio of fine-grained ferrite region was around 50% at the plate surface, however,fine-grained ferrite formation hardly occurred at mid thickness for 700°C rolled plate. FEM analysisrevealed that fine-grained ferrite distribution along the thickness can be well explained by equivalentplastic strain distribution along the plate thickness for 700°C rolled plate. Equivalent plastic strainshowed maximum value near the plate surface due to shear strain component, and it could helpsubstructure evolution and fine grained ferrite formation. On the other hand, the ratio of fine-grainedferrite region reached to 50% all through the thickness for 780°C rolled plate. Austenite as a hardersecond phase seems to promote ferrite substructure evolution even at mid thickness of the plate
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/02/17/transtech_doi~10.4028%252Fwww.scientific.net%252FMSF.558-559.607.pdf
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Influence of viral infection on the development of nasal hypersensitivity (2005)
    Oxford, UK : Blackwell Science Ltd
    Clinical & experimental allergy 35 (2005), S. 0 
    Details
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background The underlying relationship between viral infections and allergic diseases of the upper respiratory tract has not been well clarified.Methods In order to clarify the relationship between viral infection and nasal hypersensitivity, mice were sensitized with ovalbumin (OVA) and then infected intranasally with respiratory syncytial virus (RSV), after which their nasal sensitivity to histamine or antigen was examined.Results Non-sensitized mice showed transient mild nasal hypersensitivity following nasal administration of histamine after intranasal RSV inoculation. In mice sensitized with OVA, RSV infection significantly exaggerated their nasal hypersensitivity to histamine and OVA. Treatment of these mice with a neurokinin (NK)-1/NK-2 receptor antagonist, but not with anti-IL-5 antibodies, reduced their hypersensitivity. The infiltration of nasal mucosa with eosinophils was temporarily associated with accelerated rate of RSV elimination in these animals.Conclusion RSV infection induced transient nasal hypersensitivity. Several mechanisms, including impairment of nasal epithelial cells are thought to mediate this effect. In allergen-sensitized mice, RSV inoculation strongly enhanced nasal hypersensitivity.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2222.2005.02216.x
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Impairment of conditioned freezing to tone, but not to context, in Fyn-transgenic mice: relationship to NMDA receptor subunit 2B function (2005)
    Oxford, UK : Blackwell Science Ltd
    European journal of neuroscience 21 (2005), S. 0 
    Details
    ISSN: 1460-9568
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: We previously demonstrated that transgenic mice overexpressing Fyn tyrosine kinase exhibit higher seizure susceptibility and enhanced tyrosine phosphorylation of several proteins, including the N-methyl-D-aspartate (NMDA) receptor subunit 2B (NR2B). In the present study, we analysed behavioural phenotypes, especially conditioned fear responses, of Fyn-transgenic (TG) mice to better understand the role of Fyn in learned emotional behaviour. Tone-dependent conditioned freezing was significantly attenuated in Fyn-TG mice, whereas context-dependent freezing was unaffected. Neither massed nor spaced conditioning ameliorated the attenuation of tone-dependent freezing. However, the selective NR2B antagonist ifenprodil, when administered before conditioning, restored tone-dependent freezing in Fyn-TG mice at a dose that did not affect freezing in wild-type (WT) mice. These results suggest that impairment of tone-dependent conditioned freezing in Fyn-TG mice is caused by disruption of the NR2B-containing NMDA receptor function. Tyrosine phosphorylation of brain proteins, including NR2B, was enhanced in Fyn-TG mice compared with that in WT mice. We also found that ifenprodil significantly suppressed the enhanced tyrosine phosphorylation. Thus, our data support the notion that NMDA receptor activity is tightly correlated with protein tyrosine phosphorylation, and Fyn might be one key molecule that controls tone-dependent conditioned freezing through the regulation of NMDA receptor function.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1460-9568.2005.03955.x
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    Paper (German National Licenses)
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