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  • 2005-2009  (9)
Material
Years
Year
  • 1
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 284-286 (Apr. 2005), p. 481-484 
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: In vitro behavior of 30 new glasses in the system Na2O-K2O-MgO-CaO-B2O3-P2O5-SiO2 was investigated by immersing them into a simulated body fluid for 4 to168 hours. This study involved the observation of both the changes in the properties of the immersion solution and on the glasses surface after immersion. In vitro reactivity was different for each experimental glass depending on its chemical composition. By comparing these glasses to four established bioactive glasses showing different in vivo bioactivity, a fast estimation of the bioactivity of glasses can be done; thereby the optimization of bioactive glasses for various clinical applications can be developed
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 284-286 (Apr. 2005), p. 925-928 
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The crystallization tendency for 30 experimental glasses in the system Na2O-K2O-MgOCaO-B2O3-P2O5-SiO2 was studied with thermal methods, DTA, HSM and XRD. The glasses were also immersed into simulated body fluid for 8 and 72 hours. The formation of the silica-rich gel and calcium phosphate layer on the glasses were analyzed with SEM. The in vitro behavior and crystallization tendency for heat-treated glasses were then related. This information is essential for choosing glass compositions that can be manufactured to desired products with controlledbioactivity for different applications. In general, glasses with low alkali content can tolerate heattreatment without crystallization but have less initial Si-gel formation ability and show less in vitro bioactivity than glasses with high alkali content
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 361-363 (Nov. 2007), p. 225-228 
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: In vitro reactions of bundles of fibers with diameters 20-500 μm and crushed glasses offractions 500-800 μm were compared with the reactions of plates of the same bioactive glasses. Thesamples were immersed in simulated body fluid (SBF) for 2-7 days. After immersion the changeson the surfaces of the samples were observed by SEM/EDXA. Layer formation on the glass surfacewas found to vary with glass composition, sample shape and local condition of single particle/fiber.However, only some fibers or particles formed similar in vitro reaction layers as the plates. Theproduct form did not change the in vitro bioactivity of particles or fibers exposed to the bulkimmersion solution. When the glasses were used as fiber bundles or particle beds, the packingdegree and the flow of body fluids within the system interfered with the reactivity. Also a clearcorrelation between in vivo layer formation in bone and in vitro of the glass plates could be found
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Advanced materials research Vol. 39-40 (Apr. 2008), p. 341-346 
    ISSN: 1662-8985
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: A method for measuring the early stage ion release of glasses was developed in order togain information on leaching kinetics and chemical resistance of glasses in aqueous environments.A continuous flow-through-reactor was designed in which the aqueous solution is fed through a bedof glass particles and the dissolved ions continuously recorded with a sensitive on-line analysissystem.Experimental parameters, such as solvent flow rate and temperature, could easily be adjustedaccording to the needs. The flow-through-reactor system was tested with powdered samples of floatand lead glasses, E-glass and bioactive glasses 45S5 and 1-98, all of which showed very differentchemical durability in aqueous environments. The reactor was connected to inductively coupledplasma optical emission spectrometry (ICP-OES) and concentrations of the dissolved ions weremeasured simultaneously on-line every 30-40 seconds. In this work the initial stages of ion releasewere measured during the first 15 minutes of the leaching experiments at 40°C and 80°C. Theresults were compared with standard water durability test of the glasses. The dissolution of theglasses according to both methods showed similar behaviour
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 284-286 (Apr. 2005), p. 411-414 
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Biodegradable silica microspheres containing neutron activable yttrium cations wereinvestigated as a potential material for in situ radiotherapy of cancers. The sol-gel method used for preparing the microspheres allows obtaining at relative low temperatures materials of high purity and homogeneity, with controlled rate of biodegradability. The influence of yttrium on the biodegradability of the silica microspheres was studied in a simulated body fluid (SBF). The chemical durability of the microspheres was investigated under in vitro conditions and theconcentration of yttrium released from the microspheres was determined
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 396-398 (Oct. 2008), p. 115-118 
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: In this work we summarize the most important findings of the influence of glass composition, sample shape and fluid circulation on in vitro behavior of bioactive glasses in the system Na2O-K2O-MgO-CaO-B2O3-P2O5-SiO2. The sample shapes included plates, particulates, powdered glasses, glass fibers and sintered cones with interconnected porosity. The in vitro bioactivity was measured as the changes observed in the immersion solution, SBF, and the formation of reaction layers on the samples at 4 to 168 h immersion. A lower surface area to volume ratio gave smaller changes on the ion concentrations and pH of the immersion solution but thicker reaction layers on the glass surfaces. In particulate systems with circulating fluid the pH gradients in SBF were lower but surface layers more even than in static systems. The influence of glass composition on reaction layer formation as suggested by glass plates correlated with the in vitro behavior of glass particulates larger than 250 µm, porous cones and fibers when using similar SA/V ratio
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 309-311 (May 2006), p. 345-348 
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Antibacterial effects of three powdered bioactive glasses were compared by measuring the pH of the simulated body fluid in immediate contact with the glass powder particles and by cultivating four microorganisms in the powder-solution mixtures. After individual cultivation with the microorganisms the bioactive glasses showed ability to kill bacteria, but the effects were very dependent on glass composition and on the microorganism as well as on cultivation time. Theresults indicated that antimicrobial property of bioactive glasses correlates with their ability to change the pH of the body fluid in immediate contact with the glass. However, the increase in pH is not the only factor influencing the antimicrobial properties
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Advances in science and technology Vol. 49 (Oct. 2006), p. 246-251 
    ISSN: 1662-0356
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Natural Sciences in General , Technology
    Notes: Implants with long lasting bioactivity and mechanical sustainability would be of interestin several novel clinical applications. By processing bioactive glass fibers and biodegradablepolymers into 3D structures, bone formation ability of glasses and flexibility of polymers can becombined. In order to achieve desired physiological response, reactivity of bioactive glass fibersmust be specified. Bundles of fibers within the range of bioactivity were soaked in the simulatedbody fluid at stationary conditions for several time intervals after which the cross-sectional surfacesof the fibers were studied with SEM-EDXA. The reaction layers and precipitations formed on thefiber surfaces suggest that the fibers react according to three mechanisms depending on the glasscomposition. Fibers with a high in vitro bioactivity showed the formation of distinct and thick silica–rich and calcium phosphate –rich layers already at one day’s immersion. Fibers of mediumbioactivity did not show any clear silica –rich layer but a formation of calcium phosphateprecipitations or layers at one day’s immersion. Slow glasses showed sporadic calcium phosphateprecipitation only after the longest immersion times. The results indicate that the medium and slowglasses are interesting alternatives for applications where a long term mechanical durabilitysuggested by their slow reactivity in combination with their osteoconductive tendency is desired
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 330-332 (Feb. 2007), p. 173-176 
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Factors controlling the antibacterial ability of three bioactive glasses were studied bycomparing the changes in the SBF during immersion of the glasses with their response to fourmicroorganisms. After immersion of 100 mg/ml fine powder (〈45μm) of the glasses in the SBF for1, 2, 4, 8, 16, 27 and 48 hours, the immersion solutions were filtered and the pH in the bulk solutionwas measured. Ionic concentrations of Na, K, Ca, Mg, P and Si ions in the immersion solutionswere determined by ICP-OES. The antibacterial activity of the glasses showed good correlationwith the changes of the pH values in the SBF solutions. No correlation was found between the ionicconcentration and the antibacterial ability of the three glasses against the four testedmicroorganisms. The results suggest that, the antimicrobial effect of the glass powder against themicroorganisms tested is mostly dependent on the increase of the pH in the solution to valuesdetrimental for the bacteria growth
    Type of Medium: Electronic Resource
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