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  • 2005-2009  (28)
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Material
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Year
  • 1
    Electronic Resource
    Electronic Resource
    Identification of new dinucleotide-repeat polymorphisms in factor VIII gene using fluorescent PCR (2005)
    Oxford, UK : Blackwell Science Ltd
    Haemophilia 11 (2005), S. 0 
    Details
    ISSN: 1365-2516
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary.  Haemophilia A is an X-linked inherited bleeding disorder. Linkage diagnosis using polymorphic markers in the factor VIII gene is used to archive the carrier detection and prenatal diagnosis. The objective of this study was to establish the allele frequency and heterozygosity rate (HR) of two new intragenic markers (Intron 1 and 24) and other markers (Intron 13 and 22) using fluorescent PCR. Five hundred unrelated healthy women were screened and haemophilic family was studied for carrier detection and prenatal diagnosis. We observed five different alleles of Intron 1, 10 of Intron 24, nine of Intron 13 and six of Intron 22. The observed HR for Intron 1, 24, 13 and 22 were 34.0, 35.2, 53.0 and 42.6%, while the expected HR were 33.6, 36.3, 50.1 and 44.3%, respectively. Heterozygosity rate with the combined use of all four intragenic markers was 76.6% (383/500). In prenatal diagnosis of a haemophilic family, a pregnant woman was heterozygous with three intragenic (Intron 1, 13 and 22) and one extragenic St14 VNTR (DXS52) markers. She was considered to be a carrier, and she carried a male foetus by AMXY PCR and chromosome analysis of amniocytes. Foetus did not have mutant haplotype as his uncle, suggesting a normal male status. Our study demonstrates the utility of two new intragenic markers in FVIII gene for carrier detection and prenatal diagnosis of haemophilic families.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2516.2005.01064.x
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  • 2
    Electronic Resource
    Electronic Resource
    Interleukin-10 haplotype associated with total serum IgE in atopic dermatitis patients (2005)
    Oxford, UK : Munksgaard International Publishers
    Allergy 60 (2005), S. 0 
    Details
    ISSN: 1398-9995
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background:  The genetic background of atopic dermatitis (AD) is not clearly understood. Interleukin (IL)-10 is a powerful Th-2 cell cytokine produced by lymphoid cells that exerts its function by inhibiting macrophage/monocyte and T-cell lymphocyte replication and secretion of inflammatory cytokines [IL-1, tumour necrosis factor-α (TNFA), IL-6, IL-8 and IL-12].Objective:  In an effort to discover additional polymorphism(s) in genes whose variant(s) have been implicated in total immunoglobulin E (IgE) level in AD patients, we scrutinized the single nucleotide polymorphisms (SNPs) in the IL10 gene as a potent candidate for contributing to the level of IgE in serum.Methods:  We recruited 334 AD patients and assayed their serum total IgE levels using the LIPA-200 system. Four SNPs in the IL10 gene were genotyped using the single-base extension (SBE) method. Logistic regression analyses were performed with single polymorphisms and haplotypes (ht) to determine their association with the level of serum total IgE.Results:  Genetic association analysis of total serum IgE in AD patients revealed that one of the IL10 ht, IL10-ht2, was associated with decreased serum total IgE in gene dose-dependent manner (P = 0.02–0.001).Conclusions:  It was predicted that the inhibition of innate immunity by increased IL-10 production in IL10-ht2-bearing individuals might be associated with decreased total serum IgE levels among AD patients. The greater effects of IL10 ht on decreased total serum IgE levels suggest that the effect of IL-10 polymorphism might be the result of a combined genotype (ht) rather than single polymorphisms.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1398-9995.2005.00839.x
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  • 3
    Electronic Resource
    Electronic Resource
    Polymer/Clay Nanocomposites via Interface Stabilization (2007)
    s.l. ; Stafa-Zurich, Switzerland
    Solid state phenomena Vol. 121-123 (Mar. 2007), p. 1395-1398 
    Details
    ISSN: 1662-9779
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Physics
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/02/23/transtech_doi~10.4028%252Fwww.scientific.net%252FSSP.121-123.1395.pdf
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  • 4
    Electronic Resource
    Electronic Resource
    Ferroelectric Nanotube Arrays in Hexagonally Ordered Pores of Aluminum Oxide (2007)
    s.l. ; Stafa-Zurich, Switzerland
    Solid state phenomena Vol. 124-126 (June 2007), p. 1813-1816 
    Details
    ISSN: 1662-9779
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Physics
    Notes: Self-organization of a two-dimensional array of nanopores, which was formed by anodicoxidation of aluminum, was investigated quantitatively using scanning electron microscopy (SEM)images and their fast Fourier transformation analysis. The highly ordered array of nanopores withdiameters of ~60 nm was obtained by two-step anodization at an anodizing voltage of 40 V for ananodizing time of 36 h in a 0.3 M oxalic acid. A two-dimensional ordered array of ferroelectricPbTiO3 nanotubes was successfully fabricated by a spin coating of sol-gel solution into porous anodicalumina template. SEM and transmission electron microscopy images show that the nanotubes have arelatively constant wall thickness of ~15 nm with an outer diameter of ~60 nm. The present methodhas a high efficiency to fabricate an ordered nanotube array of a variety of functional metal oxidematerials in a large area
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/02/24/transtech_doi~10.4028%252Fwww.scientific.net%252FSSP.124-126.1813.pdf
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  • 5
    Electronic Resource
    Electronic Resource
    Al-Substituted Li[Li〈sub〉(1/3-x/3)〈/sub〉Cr〈sub〉x-0.05〈/sub〉M〈sub〉0.05〈/sub〉Mn〈sub〉(2/3-2x/3)〈/sub〉]O〈sub〉2〈/sub〉 Cathode Synthesized via Sol-Gel Process (2007)
    s.l. ; Stafa-Zurich, Switzerland
    Solid state phenomena Vol. 124-126 (June 2007), p. 631-634 
    Details
    ISSN: 1662-9779
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Physics
    Notes: This work reports the effect of doping aluminium in the Li[Li(1/3-x/3)Crx-0.05M0.05Mn(2/3-2x/3)]O2 (x= 0.2; M= Al), layered cathode material. The cathode material was prepared by citric acidassisted sol-gel process. The sample is characterized by TG/DTA, XRD and FESEM measurements.The Al- doped cathode has delivered an initial discharge capacity of 250 mAh/g with a currentdensity of 0.12 mA/cm2
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/02/23/transtech_doi~10.4028%252Fwww.scientific.net%252FSSP.124-126.631.pdf
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  • 6
    Electronic Resource
    Electronic Resource
    Automated Multichannel Signal Classification Systems for Ultrasonic Nondestrucitve Evaluation (2006)
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 321-323 (Oct. 2006), p. 1266-1269 
    Details
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: A key requirement in most ultrasonic weld inspection systems is the ability for rapidautomated analysis to identify the type of flaw. Incorporation of spatial correlation information fromadjacent A-scans can improve performance of the analysis system. This paper describes two neuralnetwork based classification techniques that use correlation of adjacent A-scans. The first methodrelies on differences in individual A-scans to classify signals using a trained neural network, with apost-processing mechanism to incorporate spatial correlation information. The second techniquetransforms a group of spatially localized signals using a 2-dimensional transform, and principalcomponent analysis is applied to the transform coefficients to generate a reduced dimensional featurevectors for classification. Results of applying the proposed techniques to data obtained from weldinspection are presented, and the performances of the two approaches are compared
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/01/51/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.321-323.1266.pdf
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  • 7
    Electronic Resource
    Electronic Resource
    Biomimetic Deposition of Apatite on Zr-1Nb and Ti-6Al-4V (2007)
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 534-536 (Jan. 2007), p. 1013-1016 
    Details
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Biomimetic apatite deposition behaviors on Zr-1Nb and Ti-6Al-4V plate with varioussurface conditions were examined. Both alloys were polished with abrasive papers to have differentroughness and some of them were treated in NaOH before deposition of apatites in the simulatedbody fluid. After, 10 days immersion in a SBF, NaOH treated Zr-1Nb and Ti-6Al-4V werecompletely coated with apatite. The deposition rate of apatite was higher on NaOH-treated Ti-6Al-4V than on NaOH-treated Zr-1Nb initially, but the deposition rate on Zr-1Nb accelerated after 2days and the total weight gain due to the deposition on Zr-1Nb approached to that of Ti-6Al-4V.NaOH treatment was found to enhance the deposition rate of apatite on Ti-6Al-4V significantly. Onthe other hand, the deposition rate of Zr-1Nb was not influenced by NaOH treatment. WithoutNaOH treatment, the polished Zr-1Nb with abrasive paper was found to induce more apatitenucleation than the polished Zr-6Al-4V. The presence of apatite was confirmed by XRD analysis.SEM observation revealed a conglomerated granular structure with elongate plates
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/02/14/transtech_doi~10.4028%252Fwww.scientific.net%252FMSF.534-536.1013.pdf
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  • 8
    Electronic Resource
    Electronic Resource
    Biocompatibility and Mechanical Performance of Ni-Ti (2007)
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 534-536 (Jan. 2007), p. 1617-1620 
    Details
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Biomimetic apatite deposition behaviors and mechanical performance for as-rolled andannealed Ni-Ti plates were investigated. Apatite nucleation and growth on Ni-Ti in SBF (simulatedbody fluid) was not appreciably influenced by heat treatment. But, the apatite deposition rateincreased slightly by NaOH surface treatment. The nodular apatite on the deposited layer is favoredon a macro-scale since the surface energy of polycrystalline apatite particles can be reduced byforming nodules. The weight gain after apatite deposition for Ni-Ti (0.004 g/cm2) after 10 dayswere found to be smaller that that of NaOH treated Ti-6Al-4V, but it was comparable to that of non-NaOH-treated Ti-6Al-4V (0.004 g/cm2). The stress-strain responses of annealed Ni-Ti displayed thepseudoelastic behavior associated with stress-induced martensite formation with the transition stressfor the martensite formation equal to 320 MPa. On the other hand the cold worked Ni-Ti displayedno appreciable pseudoelastic region and the yield stress was ~500MPa. A good biomimetic apatiteformation and excellent mechanical performance of Ni-Ti suggests that Ni-Ti can be an excellentcandidate material for orthopedic implants
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/02/14/transtech_doi~10.4028%252Fwww.scientific.net%252FMSF.534-536.1617.pdf
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  • 9
    Electronic Resource
    Electronic Resource
    Short Stack Performance of Intermediate Temperature - Operating Solid Oxide Fuel Cells with Hydrocarbon Fuel Processor (2007)
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 539-543 (Mar. 2007), p. 1338-1343 
    Details
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: For intermediate temperature operation, we chose an anode-supported, planar type SOFC(Solid Oxide Fuel Cell) design considering mass production with use ferritic stainless steels ascost-effective interconnects. Anode-supported single cells with thin electrolyte layer ofYSZ(Yttria-Stabilized Zirconia) were fabricated and short stacks were built and evaluated. We alsodeveloped diesel and methane autothermal reforming(ATR) reactors in order to provide fuels toSOFC stacks. Influences of the H2O/C(steam to carbon ratio), O2/C(oxygen to carbon ratio) andGHSV(Gas Hourly Space Velocity) on performances of stacks have been investigated. Performanceof the stack operated with a diesel reformer was lower than with using hydrogen as a fuel due to lowerNernst voltage and carbon formation at anode side. The stack operated with a natural gas reformershowed similar performances as with using hydrogen. Effects of various reformer parameters such asH2O/C and O2/C were carefully investigated. We found O2/C is a sensitive parameter to control stackperformance
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/02/15/transtech_doi~10.4028%252Fwww.scientific.net%252FMSF.539-543.1338.pdf
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  • 10
    Electronic Resource
    Electronic Resource
    Plasma Etching for the Application to Low-K Dielectrics Devices (2007)
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 555 (Sept. 2007), p. 113-118 
    Details
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: We present a study of the photoresist (PR) etching and the low-k materials damage using aferrite-core inductively coupled plasma (ICP) etcher, in order to develop an etching process for thelow-k dielectric devices. We reveal that the N2/O2 flow ratio and bias power affected the PR etchingrate. By Fourier transform infrared spectroscopy and HF dipping test, we investigated the effect of thegas flow ratio and bias power on the amount of etching damage to the low-k material
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/02/16/transtech_doi~10.4028%252Fwww.scientific.net%252FMSF.555.113.pdf
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