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  • 2005-2009  (8)
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Year
  • 1
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Solid state phenomena Vol. 118 (Dec. 2006), p. 109-114 
    ISSN: 1662-9779
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Physics
    Notes: Surface hardening treatment of titanium materials in use of CO gas was studied includinginvestigation of post heat treatment under vacuum. C.P. titanium, α+β type SP-700 alloy withTi-4.5%Al-3%V-2%Mo-2%Fe and β type alloy with Ti-15%Mo-5%Zr-3%Al were used. Surface hardeningwas conducted by heating these materials at 1073K for 21.6ks in Ar-5%CO gas. Subsequently, specimenssubjected to surface hardening were heated at 1073k for various time periods under vacuum. While themaximum surface hardness value was the largest in C.P. titanium and the least in SP-700 alloy, hardeninglayer thickness was the thickest in β type alloy and the thinnest in C.P. titanium. Surface hardening in C.P.titanium was brought about by solid solution hardening due to oxygen and carbon. Enrichment of theseelements in the surface layer of both titanium alloys caused continuous variations of the microstructure suchas β to α+β, or their volume fractions in the surface hardening layer. Post heat treatment at 1073K increasedthe maximum surface hardness and hardening layer thickness with an extension of the heating time in C.P.titanium, but the surface maximum hardness decreased continuously in β type titanium alloy. Post heattreatment could remove the thin oxide layer formed by surface hardening treatment
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Inc
    Journal of the American Ceramic Society 88 (2005), S. 0 
    ISSN: 1551-2916
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: In the present study, a hydrothermal hot pressing (HHP) method was used to fabricate porous hydroxyapatites with high strength. In particular, an interconnected matrix of hydroxyapatite was achieved by solution precipitation and the application of compressive stress during HHP. Hydroxyapatite samples post-sintered after this HHP treatment had a lower relative density and higher open porosity than those prepared by normal sintering. An examination of the pore characteristics suggested that the samples after HHP treatment and post-sintering had a high amount of open pores with a large and round morphology, whereas the samples prepared by normal sintering showed a denser microstructure, with a sharp-edged-pore morphology.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background  The usefulness of bone marrow cells in accelerating wound healing has not been evaluated despite increasing evidence that bone marrow contains mesenchymal stem cells that have multipotentiality to differentiate into various types of cells after they enter the microenvironment of a specific tissue (niche).Objectives  To determine the effects of bone marrow cells and occlusive dressings in promoting wound healing in rats.Methods  We investigated by grafting, biopsy and immunohistochemistry whether various types of cells derived from green fluorescent protein (GFP)-transgenic rats would differentiate into wound component cells when administered topically on the wounds of rats. We also investigated whether topical application of bone marrow cells with an occlusive dressing would accelerate the healing of wounds with exposed bones, as measured by planimetry.Results  GFP-labelled bone marrow cells contained multipotent stem cells that sufficiently differentiated into wound myofibroblasts presenting with α-smooth muscle actin in granulation tissue. Other types of cells, including myocytes, adipocytes, peripheral blood cells from buffy coat and dermal fibroblasts, did not express myofibroblast characteristics morphologically or immunohistochemically. Application of bone marrow cells and an occlusive dressing accelerated the repair of wounds with exposed bones, compared with an occlusive dressing only or with the topical administration of bone marrow cells plus a semidry to dry dressing.Conclusions  Our study indicates that bone marrow cells accelerate the healing of wounds at least in part through their differentiation into wound myofibroblasts. Thus, treatment of wounds with bone marrow cells and a supportive occlusive dressing is effective in promoting the formation of healthy granulation tissue and also for the preparation of an ideal wound bed.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Berlin, Germany : Blackwell Verlag GmbH
    Anatomia, histologia, embryologia 34 (2005), S. 0 
    ISSN: 1439-0264
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The brain extracellular matrix (ECM) has attracted growing interest due to its highly regulated spatiotemporal expression during development and maturation of central nervous system. The present study deals with the post-natal appearance and transformation into adult distribution patterns of the ECM components related to proteoglycans (PGs) and glycoproteins (GPs) in the retrosplenial cortex (RSC) of albino rats at birth (P0), 1 week (P1), P2, P3, P4, P5, P6, P7 and P8. The differentiating PGs and GPs components of the ECM were shown to make their appearance as early as 1–2 weeks post-natally. At this developmental stage, these components of the ECM appeared in association with some neurons and glia cells or diffusely localized at the neutrophill. Interestingly, Golgi complexes of labelled neurons were usually stained with lectin VVA or WFA, and this labelling dramatically disappeared on reaching P4. During P2–3, the pericoated neuronal cells underwent a progressive increment in number, and presented an inside-out pattern of migration and differentiation (toward the V-II cortical layers). On reaching P4, most of the coated neurons appeared distributed into the cortical layer IV and II. At a later stage (P5–8), the overall density and intensity of labelled neurons progressively increased and apparently reached the adult stage of development. They also displayed the usual differential labelling characteristics, after using the cationic iron colloid/lectin staining, for the first time at this juncture. The present findings indicated that the perineuronal ECM components are significantly correlated with age and suggest a possible developmental or biological significance including promotion of migration, as well as functional maturation of the retrosplenial neurons.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Berlin, Germany : Blackwell Verlag GmbH
    Anatomia, histologia, embryologia 34 (2005), S. 0 
    ISSN: 1439-0264
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: One hundred and twenty years ago, Camillo Golgi described reticular or fenestrated sheaths of extracellular matrix (ECM), enwrapping the cell bodies, axon initial segments and proximal dendrites of certain pyramidal and non-pyramidal neurons in the adult mammalian central nervous system. Such structures, currently termed perineuronal nets (PNs), are preferentially associated with GABAergic, parvalbumin-containing fast-spiking inhibitory types of cells, and mostly expressing the Kv3.1 subunit of voltage-gated potassium channels. Although some neuroanatomists validated the existence of the PNs on selected neurons in the adult brain, there was a lack of agreement concerning their origin, composition and function. Recent data suggest that PNs result from the visualization of ECM molecules that are confined to the space interposed between glial processes and the nerve cells that they outline. The substance confined to these spaces could be visualized selectively by antibodies directed to glycoproteins, proteoglycans, markers for hyaluronan, some plant lectins recognizing N-acetylgalactosamine or by monoclonal antibodies directed to epitopes on unknown molecules. The PNs appear only after birth, which they could serve as recognition molecules between certain neurons and their surrounding cells. Other putative roles include stabilization of synapses, maintenance of cellular relationships in the adult brain, concentration of growth factors around certain neurons, generation of a polyanionic ion-buffering microenvironment, as well as prevention of extracellular-space occlusion and the formation of certain link with the intracellular cytoskeleton.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Berlin, Germany : Blackwell Verlag GmbH
    Anatomia, histologia, embryologia 34 (2005), S. 0 
    ISSN: 1439-0264
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Perineuronal nets (PNs) of condensed extracellular matrix (ECM) have been shown to characterize the microenvironment of individual neurons and the chemoarchitecture of some brain regions. In the present study, PNs in the hippocampus were visualized with a cationic iron colloid method for sulphated proteoglycan content and a plant lectin from Vicia villosa agglutinin (VVA) for N-acetylgalactosamine containing glycoconjugates. The ECM molecules were organized in reticular coats (PNs) around non-pyramidal cells in the Ammons horn (Corneu Ammons, CA) and subicular region, in addition to pyramidal neurons located in CA2 and CA3 regions. CA2 stratum pyramidale exhibited the most intense staining of its PNs and a diffuse intervening neutrophil labelling, while CA3 region showed a graded fashion of staining intensity. The subiculum displayed intensely stained perineuronal coats. Notably, the hippocampal perineuronal nets revealed overlapped staining characteristics with both staining methods. However, cell coats of the subicular neurons showed various degrees of labelling characteristics with both markers. It is suggested that the PNs in the hippocampus are correlated with the fast spiking inhibitory GABAergic neurons and their target pyramidal cells, and this is important to keep the excitatory elements under control and therefore control the information processes within the hippocampus.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Berlin, Germany : Blackwell Verlag GmbH
    Anatomia, histologia, embryologia 34 (2005), S. 0 
    ISSN: 1439-0264
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Reticular or net-like perineuronal coatings enriched with proteoglycans (PGs) and/or glycoproteins (GPs) were demonstrated to ensheathe cell surfaces of certain neuronal circuits in the central nervous system of mammals, reptiles and fishes. In this investigation the coated or ensheathed neurons in the retrosplenial cortex (RSC) of adult albino rats were quantified using a computerised analysing system. They were distributed throughout the II–IV cortical layers and comprised about 24.25% of total neurons. The perineuronal coatings were expressed with a cationic iron colloid (CIC), CIC/Bodian staining and with certain plant lectins from Vicia villosa agglutinin ‘VVA’, Wisteria floribunda agglutinin ‘WFA’ and Glycine max agglutinin ‘SBA’. The mean number of coated neurons per unit area (UA, 60.15 μm2), as labelled by CIC or CIC/Bodian, VVA, WFA and SBA staining was 4.01 ± 0.42, 4.43 ± 0.37, 6.45 ± 0.87, 5.70 ± 0.73 and 3.91 ± 0.53, respectively. In addition, labelling indicated by the aforementioned stains were 10.55%, 11.55%, 16.97%, 15.00% and 10.23%. Notably, the labelled retrosplenial neurons underwent a non-significant increase with progression of animal age at the first post-natal year. However, they declined thereafter toward senility. Qualitatively, there were three types of coated neuronal circuits at the RSC of rats: PGs-, GPs- and PGs/GPs- coated cells, which comprised 9%, 64% and 27%, respectively. This data indicated that the GPs- and GPs/PGs- coated neurons in the RSC of albino rats were more prevalent than the PGs- coated ones.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 317-318 (Aug. 2006), p. 41-44 
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: 12 mol%CeO2 based composites were fabricated by a pressureless sintering technique and post-HIPtreatments. The mixture of 12CeO2-ZrO2/3Y2O3-ZrO2 (= 80 wt%/20 wt%) powders from various methods wereprepared by a ball milling technique and consequently sintered at 1400[removed info] in air atmosphere and post-HIP treatmentat 1350[removed info]. The 12Ce-ZrO2/Y-ZrO2 composites sintered from mixture of 12CeO2-ZrO2 powder and 3Y2O3-ZrO2powders possessed the high strength over 1300 MPa and also high fracture toughness over 11 MPam1/2. Furthermore,the significant inhibition of the ZrO2 phase transformation of tetragonal to monoclinic phase under an aqueoushydrothermal condition at 150[removed info] was obtained for these 12Ce-ZrO2/Y-ZrO2 composites prepared from this method.Microstructural observation was in detail performed by TEM and EDS
    Type of Medium: Electronic Resource
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