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  • 2005-2009  (6)
  • 1
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Solid state phenomena Vol. 134 (Nov. 2007), p. 263-266 
    ISSN: 1662-9779
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Physics
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    British journal of dermatology 153 (2005), S. 0 
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background  Photodynamic therapy (PDT) is available for the treatment of various skin tumours and other skin diseases. Ultraviolet (UV) irradiation induces DNA damage, cyclobutane pyrimidine dimers (CPD) (6-4) photoproducts (6-4PP) and 8-hydroxy-2′-deoxyguanosine (8-OHdG), all of which are carcinogenic for the skin. However, effects of PDT on DNA damage and carcinogenesis are unclear.Objectives  To compare the production of photoproducts and the induction of skin tumours in mouse epidermis treated with UVB or PDT.Methods  We performed UVB irradiation or ATX-S10(Na)–PDT on the skin of 20 hairless mice, in each case, and analysed DNA damage and tumour induction.Results  After a single irradiation of UVB on mouse skin, CPD, 6-4PP and 8-OHdG were detected in the nuclei of keratinocytes. In contrast, PDT-treated mouse keratinocytes showed induction of 8-OHdG, but not of CPD or 6-4PP. Skin tumours induced by UVB irradiation (3 kJ m−2 three times weekly) were observed following 15 weeks of irradiation (mean ± SEM tumour incidence 3·2 ± 1·8%; tumour number 3·2 ± 1·6 per mouse) and increased depending on irradiation times and doses. Following 30 weeks of UVB irradiation (3 kJ m−2 three times weekly), mean ± SEM tumour incidence and tumour number were 28·7 ± 4·8% and 14·2 ± 2·8% per mouse, respectively. Although skin tumours were also detected in PDT-treated mouse skin following 80 weeks of treatment (mean ± SEM tumour incidence 9·1 ± 1·8%; tumour number 12·2 ± 2·3 per mouse), the number of tumours was not statistically different from untreated mouse skin (mean ± SEM tumour incidence 4·1 ± 3·8%; tumour number 5·2 ± 3·3 per mouse).Conclusions  PDT induced 8-OHDG but not CPD or 6-4PP, and was shown to be a relatively safe modality following multiple applications to mouse skin.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 475-479 (Jan. 2005), p. 1463-1466 
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The effect of helium on irradiation damage behavior in Fe-Cr-Mn(W,V) steel wasinvestigated by electron/helium ion dual-beam irradiation. The results indicate that helium can promote the increase of dislocation density and enhance the void nucleation and void swelling of Fe-Cr-Mn(W、V) alloy. The segregation of solute elements near grain boundary was suppressed by existence of helium. Also the interface of carbide-matrix migration and the change of solute concentration near the interface were observed during dual-beam irradiation
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 475-479 (Jan. 2005), p. 1455-1458 
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The effects of helium and aging treatment on radiation damage behavior in low activation Fe-Cr-Mn ( W, V) alloy were investigated by electron and helium ion dual-beam irradiation in a high voltage electron microscope. Specimens were aged at 673 K, 823 K and 923 K for 1000, 3000 and 10000 hours. Electron and He ion dual-beam irradiations were performed at 627 K to 10 dpa. M23C6 type carbides were precipitated in the aged specimens, and the amount of the precipitates was increased with increasing aging temperature and aging time. He bubbles were formed during dual-beam irradiation in all of the specimens. The cavity swelling under dual-beam irradiations was increased with increasing the aging temperature and aging time. It was suggested that cavity swelling is closely related to the concentration of solutes such as Cr and C in the matrix, namely cavity growth rate becomes higher with decreasing of the solutes in solution
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 475-479 (Jan. 2005), p. 1425-1428 
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The high Mn-Cr austenitic steel for structure material of nuclear and/or fusion reactors from the point of view of the reduced radio-activation has been irradiated by using three irradiation modes of electron-beam irradiation, electron-beam irradiation after He-injection and electron/He+-ion dual-beam irradiation in 1250kV high voltage electron microscope (HVEM) connected with an ion accelerators to study the effect of He-injection on irradiation damage. Irradiation-induced segregation analyses were carried out by an energy dispersive X-ray analyzer (EDX) in a 200kV FE-TEM with beam diameter of about 0.5nm. Void formation was not observed in each irradiation condition. Grain boundary migration was observed in the case of electron/He+-ion dual-beam irradiation. Irradiation-induced segregations of Cr and Mn at grain boundary were observed in each irradiationcondition. The amounts of Cr and Mn segregation decreased in the cases of electron-beam irradiation after He-injection compared with other irradiation conditions
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    The European physical journal 39 (2005), S. 511-518 
    ISSN: 1434-6052
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract. The Bethe ansatz equations for the spin 1/2 Heisenberg XXZ spin chain are numerically solved, and the energy eigenvalues are determined for the antiferromagnetic case. We examine the relation between the XXZ spin chain and the massless Thirring model, and show that the spectrum of the XXZ spin chain has a gapless excitation while the regularized Thirring model calculated with the Bogoliubov transformation method has a finite gap. This finite gap spectrum is also confirmed by the Bethe ansatz solution of the massless Thirring model.
    Type of Medium: Electronic Resource
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