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  • 1
    Digitale Medien
    Digitale Medien
    Trioxalatoruthénate(III) de potassium 4,5-hydraté (1986)
    Oxford [u.a.] : International Union of Crystallography (IUCr)
    Acta crystallographica 42 (1986), S. 982-984 
    Details
    ISSN: 1600-5759
    Quelle: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Thema: Chemie und Pharmazie , Geologie und Paläontologie , Physik
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1107/S0108270186093794
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  • 2
    Digitale Medien
    Digitale Medien
    Does caffeine prevent hypoxaemic episodes in premature infants? (1988)
    Springer
    European journal of pediatrics 147 (1988), S. 288-291 
    Details
    ISSN: 1432-1076
    Schlagwort(e): Premature infant ; Caffeine ; Hypoxaemia ; Bradycardia
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Fifty spontaneously breathing, preterm infants 48h old, of 32 weeks' gestation or less, were assigned randomly to receive caffeine citrate (loading dose 20 mg/kg, maintenance dose 10 mg/kg per day) or a placebo (NaCl 0.9%). The study hypothesis was that caffeine reduces the proportion of infants with recurrent hypoxaemic episodes (decrease in transcutaneous PO2 of 20% within 20ss) from 50% to 25%. Transcutaneous oxygen tension (tcPO2) and heart rate were recorded continuously for 50h and analysed by computer. The two groups were similar in gestational age, birth weight, delivery mode, sex distribution, and Apgar scores. The mean serum concentration (±SD) of caffeine 2h after the second maintenance dose was 96.0 (±34.5) μmol/l in the group receiving caffeine and 9.3 (±12.8) μmol/l in the group receiving a placebo. The mean proportion of infants with more than six hypoxaemic episodes per 12h in the caffeine groups was higher (57%) than in the control group (51%). The mean proportion of infants with more than six episodes of bradycardia per 12h was not statistically different in the caffeine group (79%) from the control group (86%). Our results suggest that prophylactic caffeine has little if any effect on the risk of developing hypoxaemic episodes and bradycardia in small preterm infants and the supposed 50% reduction which was considered clinically important at the start of the trial can be rejected with confidence.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00442697
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  • 3
    Digitale Medien
    Digitale Medien
    Neonatal metatarsus adductus, joint mobility, axis and rotation of the lower extremity in preterm and term children 0–5 years of age (1988)
    Springer
    European journal of pediatrics 148 (1988), S. 19-23 
    Details
    ISSN: 1432-1076
    Schlagwort(e): Metatarsus adductus ; Axis ; Rotation ; Lower extremity ; Children, term and preterm
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract A total of 484 premature children and a control group of 114 healthy term children underwent orthopaedic follow-up from birth to 5 years of age. At birth, metatarsus adductus was found to be more frequent in twins than in single infants (41% vs 16%; P〈0.01), but occurred with equal frequency in single preterm and term infants (16% vs 12%). By 5 years of age, metatarsus adductus had resolved in all the term but only in 81% of the preterm children (P〈0.05). In the preterm and term groups, knee axis (mean intermalleolar distance 22.0 mm vs 20.1 mm), tibial torsion (mean angle-1.2° vs +0.6°) and angle of gait (mean angle +1.5° vs +0.7°) at 5 years were statistically insignificant. Hip function at 5 years was similar in normal preterm and term children but significantly decreased in preterm children with cerebral palsy, more so with regard to abduction (56° vs 39°, P〈0.05) and extension (22° vs 8°, P〈0.01). The difference between the sexes was insignificant in both the preterm and term groups.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00441806
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  • 4
    Digitale Medien
    Digitale Medien
    Infants born to mothers with antibodies againstBorrelia burgdorferi at delivery (1989)
    Springer
    European journal of pediatrics 148 (1989), S. 426-427 
    Details
    ISSN: 1432-1076
    Schlagwort(e): Borrelia burgdorferi ; Pregnancy ; Infection ; Infant outcome
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract A serological survey over a 1-year period of 1416 mothers at delivery and their 1434 offspring for the presence of anti-Borrelia burgdorferi antibodies revealed a prevalence of 0.85%. Clinically active Lyme disease during pregnancy was found in 1 of these 12 women with elevated titres and the child was born with a ventricular septal defect. Of six affected children, two had hyperbilirubinaemia, one muscular hypotonia, one was underweight for gestational age, one was macrocephalic, and one had supraventricular extrasystoles. Anomalous findings could not be attributed toB. burgdorferi due to a lack of serological evidence of intrauterine infection. Our data do not imply the need for serological screening in pregnancy, however, the importance of recognition and treatment of Lyme disease in pregnancy is emphasized.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00595903
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  • 5
    Digitale Medien
    Digitale Medien
    Feasibility of synchrotron radiation computed tomography on rats bearing glioma after iodine or gadolinium injection (2000)
    Springer
    European radiology 10 (2000), S. 1487-1492 
    Details
    ISSN: 1432-1084
    Schlagwort(e): Key words: Synchrotron – Iodine – Gadolinium – CT – Brain – Glioma
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract. The purpose of this work was to demonstrate the feasibility of a new imaging technique called synchrotron radiation computed tomography (SRCT). This technique leads to a direct assessment of the in vivo concentration of an iodine- or gadolinium-labeled compound. Rats bearing C6 glioma were imaged by MRI prior to the SRCT experiment. The SRCT experiments were performed after a 1.3 g I/kg (n = 5) or a 0.4 g Gd/kg (n = 5) injection. Finally, brains were sampled for histology. The SRCT images exhibited contrast enhancement at the tumor location. Ten minutes after injection, iodine and gadolinium tissular concentrations were equal to 0.80 ( ± 0.40) mg/cm3 and 0.50 ( ± 0.10) mg/cm3, respectively in the peripheral area of the tumor (respective background value: 0.20 ± 0.02 to 0.10 ± 0.01). Correlation to MRI and histology revealed that the contrast uptake occurred in the most vascularized area of the tumor. The present study summarizes the feasibility of in vivo SRCT to obtain quantitative information about iodine and gadolinium-labeled compounds. Beyond brain tumor pathology, the SRCT appears as a complementary approach to MRI and CT, for studying iodine- and gadolinium-labeled compounds by the direct achievement of the tissular concentration value in the tissue.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/s003300000509
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  • 6
    Digitale Medien
    Digitale Medien
    Measurements of genetic variability for symbiotic dinitrogen fixation in fieldgrwon fababean (Vicia faba L.) using a low level15N-tracer technique (1988)
    Springer
    Plant and soil 106 (1988), S. 269-276 
    Details
    ISSN: 1573-5036
    Schlagwort(e): 15N ; nitrogen fixation ; plant breeding ; Vicia faba
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Land- und Forstwirtschaft, Gartenbau, Fischereiwirtschaft, Hauswirtschaft
    Notizen: Abstract Before starting a breeding program aimed at improving the nitrogen nutrition ofVicia faba, the authors tried an alternative technique to the acetylene reduction assay, to measure some genetic variability in the plant material. The quantity of dinitrogen fixed by several cultivars ofVicia faba was estimated using a low enrichment15N tracer method and high precision15N mass spectrometry. The fababeans were cultivated for two years in two different soils. The percentage of fixed dinitrogen in the seed varied between genotypes from 40 to 83% of the total nitrogen and was positively correlated with the total seed nitrogen (r=0.64 to 0.86). A highly significant positive correlation was also found between the total seed nitrogen and the quantity of fixed dinitrogen in the seed (r=0.95 to 0.99). The technique used to measure dinitrogen fixation proved to be useful and reliable enough to discriminate between various genotypes, grown over a period of two years in two different soils. However, several non-fixing control plants showed significant differences in their15N enrichment and the problem of choosing a good reference plant was raised and discussed.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF02371223
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