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  • 1
    Electronic Resource
    Electronic Resource
    Ferrochelatase at the millennium: structures, mechanisms and [2Fe-2S] clusters (2000)
    Springer
    Cellular and molecular life sciences 57 (2000), S. 1909-1926 
    Details
    ISSN: 1420-9071
    Keywords: Key words. Ferrochelatase; heme synthesis; iron sulfur cluster; metallation; porphyria.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract. Ferrochelatase (E.C. 4.99.1.1, protoheme ferrolyase) catalyzes the insertion of ferrous iron into protoporphyrin IX to form protoheme (heme). In the past 2 years, the crystal structures of ferrochelatases from the bacterium Bacillus subtilis and human have been determined. These structures along with years of biophysical and kinetic studies have led to a better understanding of the catalytic mechanism of ferrochelatase. At present, the complete DNA sequences of 45 ferrochelatases from procaryotes and eucaryotes are available. These sequences along with direct protein studies reveal that ferrochelatases, while related, vary significantly in amino acid sequence, molecular size, subunit composition, solubility, and the presence or absence of nitric-oxide-sensitive [2Fe-2S] cluster.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/PL00000672
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  • 2
    Electronic Resource
    Electronic Resource
    Bacterial Indicator Occurrence and the Use of an F+ Specific RNA Coliphage Assay to Identify Fecal Sources in Homosassa Springs, Florida (2000)
    Springer
    Microbial ecology 39 (2000), S. 56-64 
    Details
    ISSN: 1432-184X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract A microbiological water quality study of Homosassa Springs State Wildlife Park (HSSWP) and surrounding areas was undertaken. Samples were collected in November of 1997 (seven sites) and again in November of 1998 (nine sites). Fecal bacterial concentrations (total and fecal coliforms, Clostridium perfringens, and enterococci) were measured as relative indicators of fecal contamination. F+-specific coliphage genotyping was performed to determine the source of fecal contamination at the study sites. Bacterial levels were considerably higher at most sites in the 1997 sampling compared to the 1998 sampling, probably because of the greater rainfall that year. In November of 1997, 2 of the 7 sites were in violation of all indicator standards and guidance levels. In November of 1998, 1 of 9 sites was in violation of all indicator standard and guidance levels. The highest concentrations of all fecal indicators were found at a station downstream of the animal holding pens in HSSWP. The lowest levels of indicators were found at the Homosassa Main Spring vent. Levels of fecal indicators downstream of HSSWP (near the point of confluence with the river) were equivalent to those found in the Southeastern Fork and areas upstream of the park influences. F+ specific RNA coliphage analysis indicated that fecal contamination at all sites that tested positive was from animal sources (mammals and birds). These results suggest that animal (indigenous and those in HSSWP) and not human sources influenced microbial water quality in the area of Homosassa River covered by this study.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002489900193
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    The problem of technological barriers (2000)
    Bingley : Emerald
    Kybernetes 29 (2000), S. 576-594 
    Details
    ISSN: 0368-492X
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Computer Science
    Notes: Gives an insight into the thinking of the 1960s and written at a time when subsequent advances and developments could not have been predicted with any degree of certainty. Provides a view of the "new concepts" of cybernetics and discusses their implications. Reproduced without any alterations, the prize-winning essay deals with science and technology; technological time-lag; status of technologists; industrial and academic research; interaction of technologies; the cybernetic revolution; education and the environmental barrier; professional obsolescence; and finally, the purpose of education.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1108/03684920010333062
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  • 4
    Electronic Resource
    Electronic Resource
    Higher Education in Technology (1963)
    [s.l.] : Nature Publishing Group
    Nature 198 (1963), S. 233-238 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] II WHEN we consider British univ ersities in the context of higher education in the Western World, two features stand out: the small number of universities and the relatively small numbers of students in them. Britain has the smallest number of universities in proportion to its population in ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/198233a0
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  • 5
    Electronic Resource
    Electronic Resource
    Higher Education in Technology (1963)
    [s.l.] : Nature Publishing Group
    Nature 198 (1963), S. 128-133 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] (I) THE past decade has seen the emergence, in outline, of a new structure of technological education in Britain accompanied by an increased public interest in higher education. Although the path to a modified and improved structure appears to be strewn with the debris of bygone ideas and ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/198128a0
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  • 6
    Electronic Resource
    Electronic Resource
    Managerial and Commercial Education (1963)
    [s.l.] : Nature Publishing Group
    Nature 199 (1963), S. 953-957 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] THE profound changes taking place in post-war Britain have at last reached the very much neglected field of managerial and commercial education. Although extensive pockets of public indifference and traditional muddle appear to dominate the scene, some progress has already been made. There is, for ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/199953a0
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  • 7
    Electronic Resource
    Electronic Resource
    The Field-Slug Agriolimax reticulatus as a Vector of the Lungworm Cystocaulus ocreatus (1960)
    [s.l.] : Nature Publishing Group
    Nature 185 (1960), S. 180-180 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] C. ocreatus was recorded only recently in British sheep3. Afterwards a study of the transmission of infection under natural conditions was commenced at Weybridge. Lungworm-free lambs were grazed with infected ewes and, at frequent intervals, faecal samples from the lambs were examined for first ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/185180a0
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  • 8
    Electronic Resource
    Electronic Resource
    Galileo Galilei (1564–1642) (1964)
    [s.l.] : Nature Publishing Group
    Nature 201 (1964), S. 653-657 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] “Science as an important force began with Galileo”—BERTRAND RUSSELL IN the ninth and the tenth centuries A.D. Arabic science and civilization were at their peak in Spain, Northern Africa and the Middle East, while Christian Europe was engulfed in a barbaric darkness. Arabic was ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/201653a0
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  • 9
    Electronic Resource
    Electronic Resource
    First report of ramorum bleeding canker on Quercus falcata, caused by Phytophthora ramorum (2004)
    Oxford, UK : Blackwell Science Ltd
    Plant pathology 53 (2004), S. 0 
    Details
    ISSN: 1365-3059
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-3059.2004.01079.x
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  • 10
    Electronic Resource
    Electronic Resource
    Blaise Pascal (1623–62) (1962)
    [s.l.] : Nature Publishing Group
    Nature 195 (1962), S. 847-851 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] "The heart has its reasons of which the reason knows nothing" (Pensee, 477). IN the seventeenth century France was the most unified State on the Continent and numerically by far the strongest power in Europe. Thanks to her large population and her wealth, France succeeded Spain as the dominant ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/195847a0
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