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  • 1
    ISSN: 1420-908X
    Keywords: Key words:M. bovis BCG — Neutrophil — Eosinophil — Inflammation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Objective and Design: The host response to Mycobacteria focuses on the development of cell-mediated immunity and granuloma formation. Here, we investigated the onset of cellular responses to mycobacteria in murine pleurisy.¶Material: Distinct mouse strains previously described as Bcg susceptible or resistant were inoculated intrathoracically with different doses of live M. bovis BCG.¶Methods: At various time intervals, cells harvested from the inflammatory site were identified and ultra-structurally analysed.¶Results: BCG-induced pleurisy had two peaks of cellular influx at 1 and 15 days after infection. At the first half hour, macrophages were found to be heavily infected. Neutrophil arrival started after 2 h of infection and peaked at 4 h. At this time, neutrophils were found ingesting mycobacteria exclusively with a high infecting dose. BCG was potently more eosinophilotactic in Bcg susceptible mice than in the resistant ones and to other well known eosinophilia inducers: IL-5, PAF-acether or LPS.¶Conclusions: Mycobacterial load and mouse susceptibility seem to determine the early granulocyte dynamics in the lesion.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Pure and applied geophysics 157 (2000), S. 1009-1038 
    ISSN: 1420-9136
    Keywords: Key Words: Landslides, slope stability, boundary element, continuum mechanics, shear fracture.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Notes: Abstract —We analyze the initiation and enlargement of the rupture surface of translational landslides as a fracture phenomenon using a two-dimensional boundary-element method. Both processes are governed largely by the stress field and the pre-existing planes of weakness in a slope. Near the ground surface, the most compressive stress becomes either parallel or perpendicular to the slope, depending on the topography and regional stresses. The shear stress available to drive slope-parallel sliding in a uniform slope thus is small, and therefore pre-existing weaknesses are required in many cases for sliding. Stresses in a uniform slope favor the initiation of sliding near the slope base. Sliding can progress upslope from there in retrogressive fashion. Most slopes are not uniform and notches in a slope will concentrate stresses and generally promote sliding there. As the region of sliding at depth enlarges, the stress concentration near the edge of the area of slip will tend to rise. Stress concentrations can become sufficient to open fractures above and below a basal slide plane, in keeping with observations. If one tip of a slide plane intersects the ground surface, then stresses near the other tip can increase markedly, as can slip. Our analyses show that slope-parallel sliding along a plane at depth will cause downslope extension in the upslope half of a slide mass and shortening in the downslope half, consistent with observations. Displacement profiles that could be interpreted as rotational can result from sliding along such a plane, however careful analysis of surface deformation can be used to understand sliding at depth.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Pure and applied geophysics 157 (2000), S. 989-1007 
    ISSN: 1420-9136
    Keywords: Key Words: Oundary element, continuum mechanics, slope stability, stress analysis, topography.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Notes: Abstract —Elastic stresses arising from gravitational loads in a two-dimensional slope of arbitrary shape are calculated easily using a displacement-discontinuity boundary element method (BEM). A long stress-free crack simulates the topographic surface. Gravity-induced stresses (i.e., body forces) in a laterally confined body are simulated by vertical and horizontal “far-field” stresses equal to ρgy and [ν/(1-ν)]ρgy, respectively. Here ρ is material density, ν is Poisson’s ratio, g is gravitational acceleration, and y is elevation, with y = 0 along the surface far from a ridge top or valley floor. BEM stress solutions compare well with analytical solutions for symmetric topography based on conformal mapping. Our analyses indicate that slope failures are likely to initiate near the bases of bedrock ridges and to be widespread along the slopes of gentle valleys cut in bedrock. The BEM method can be applied to the slopes of arbitrary shape and steepness, and it is well suited for evaluating the near-surface propagation of fractures or fracture-like structures, such as dikes and landslide failure surfaces. Our analysis also highlights the critical importance of properly accounting for the boundary conditions in a boundary value problem.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1292-895X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract: We report the results of small-angle neutron scattering (SANS) studies on aqueous solutions of spherical polyelectrolyte micelles formed by association of charged-neutral diblock copolymers. The neutral moieties are found to self-assemble into small dense spheres (cores of the micelles) whose sizes are independent of the polymer concentration c. In the dilute regime, c〈c *, where c* is the overlap concentration of the micelles, the conformation of the charged groups, which form the corona of the micelles, is found to be extended. A liquid-like order is observed over a wide concentration range spanning from the dilute regime to the concentrated regime. For c〉c *, polyelectrolyte correlations appear at smaller spatial scales and coexist with the liquid-like order. These results suggest that for dense brushes, above c*, the rod-like statistics of the charged chains begin to disappear due to contraction of corona arms or by interpenetration of coronae. For less dense brushes, the charged chains are found to be extended up to concentrations far above c*, before the progressive development of polyelectrolyte correlations.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    The European physical journal 2 (2000), S. 153-159 
    ISSN: 1292-895X
    Keywords: PACS. 68.10.Et Interface elasticity, viscosity, and viscoelasticity - 83.50.Lh Interfacial and free surface flows; slip
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract: The surface shear viscosity of monolayers formed at the surface of water by adsorbed polyethyl- eneoxyde and by stearic acid is measured as a function of the surface pressure of the monolayer using a new surface viscometer. The principle of the viscometer is the measurement of the drag force on a circular disk undergoing a uniform translation at the water surface: a hydrodynamic model based on the lubrication approximation allows a calculation of the surface viscosities from the absolute measurement of the drag forces.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1432-0533
    Keywords: Key words Experimental autoimmune encephalomyelitis ; Neuropathology ; Cerebellum ; Brain stem ; Myelin proteolipid protein
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Experimental autoimmune encephalomyelitis (EAE) is an autoimmune demyelinating disease that can be induced in a variety of animal species and which is commonly used as an animal model of multiple sclerosis. In rodent EAE models, the clinical disease is typified by ascending paralysis; however, other clinical patterns can also be observed by inducing disease with particular peptides of myelin proteolipid protein (PLP) or myelin oligodendrocyte glycoprotein. Here we describe EAE induced in C3H/HeJ mice by inoculation with residues 190–209 of PLP. This form of EAE is manifested clinically by a movement disorder, with axial rotation of the head and trunk. Histologically, this form of EAE is characterized by predominant cerebellar or brain stem involvement, depending on whether EAE is induced by active immunization with the PLP peptide, or by passive transfer of T cells specific for the peptide. The inflammatory cell infiltrate is composed of polymorphonuclear cells and mononuclear cells. This rotatory form of EAE may be a useful model for studying the neuropathological characteristics of multiple sclerosis affecting the brain stem and cerebellum.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 321-324 (Jan. 2000), p. 1010-1015 
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1090-6487
    Keywords: 75.70.Ak ; 76.80.+y
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Depth-selective conversion electron Mössbauer spectroscopy was used to study magnetic properties of the thin surface layers of the α-Fe2O3 and FeBO3 single crystals. An analysis of the experimental spectra indicates that the magnetic properties of the layers at a depth of more than ∼100 nm from the surface are similar to the properties of crystal bulk, and the corresponding spectra consist of narrow lines. The lines gradually broaden as the crystal surface is approached. The spectra of the ∼10-nm-thick surface layers consist of broad lines, indicating a wide distribution δ=2.1 T of the effective magnetic field about its mean value of 32.2(4) T. The experimental spectra were used to determine the effective magnetic fields (H eff) for the iron ions situated in the surface layers of thickness ∼100 nm. The effective fields in these layers were found to gradually decrease at room temperature (291 K) as the crystal surface was approached. The H eff values in the 2.4(9)-nm-thick surface layer of the α-Fe2O3 crystal and 4.9(9)-nm layer of FeBO3 are 0.7(2) and 1.2(3)%, respectively, smaller than for the nuclei of the ions in the bulk of these crystals.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1090-6487
    Keywords: 75.30.Kz ; 75.40.−s ; 68.35.Rh
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The behavior of the surface and near-surface layers of macroscopic FeBO3 single crystals is studied over the temperature range from 291 K to Neél temperature (T N ) using depth-selective conversion-electron Mössbauer spectroscopy. Three different phases or states, namely, an antiferromagnetically ordered phase (similar to the crystal bulk state), a surface phase, and a transition layer between them coexist near the Neél point in a surface layer ∼500 nm thick. The critical parameters found for the bulk phase agree well with the theoretical critical index νth≅0.63 predicted by the 3D Ising model. As the crystal surface is approached, the critical parameter β increases to 0.51(2) but remains smaller than the value of β=0.8 for the surface of a semi-infinite Heisenberg model. Therefore, the effective dimensionality of the system, being equal to 3 in the bulk, decreases at the crystal surface.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 0992-7689
    Keywords: Meteorology and atmospheric dynamics (middle atmosphere dynamics; waves and tides)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Notes: Abstract Meteor radars located in Bulgaria and the UK have been used to simultaneously measure winds in the mesosphere/lower-thermosphere region near 42.5°N, 26.6°E and 54.5°N, 3.9°W, respectively, over the period January 1991 to June 1992. The data have been used to investigate planetary waves and diurnal and semidiurnal tidal variability over the two sites. The tidal amplitudes at each site exhibit fluctuations as large as 300% on time scales from a few days to the intra-seasonal, with most of the variability being at intra-seasonal scales. Spectral and cross-wavelet analysis reveals closely related tidal variability over the two sites, indicating that the variability occurs on spatial scales large compared to the spacing between the two radars. In some, but not all, cases, periodic variability of tidal amplitudes is associated with simultaneously present planetary waves of similar period, suggesting the variability is a consequence of non-linear interaction. Calculation of the zonal wave number of a number of large amplitude planetary waves suggests that during summer 1991 the 2-day wave had a zonal wave number of 3, but that during January/February 1991 it had a zonal wave number of 4.
    Type of Medium: Electronic Resource
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