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  • 1
    Electronic Resource
    Electronic Resource
    Masticatory movement in two cases with unusual alignment of the maxillary canine (2000)
    Oxford, UK : Blackwell Science Ltd
    Journal of oral rehabilitation 27 (2000), S. 0 
    Details
    ISSN: 1365-2842
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Masticatory function was analysed before and after orthodontic treatment in two cases where tooth alignment remained unusual after treatment. The Sirognathograph Analyzing System® was used to analyse the masticatory function. In both cases, the right maxillary first premolar was located where the maxillary canine is normally positioned. The results of orthodontic treatment were satisfactory both morphologically and aesthetically, and masticatory function was greatly improved. However, some problems remained in the mandibular movement due to the abnormal contact between the mandibular teeth and the maxillary first premolar. These findings support the need for examination of masticatory function when treating patients with an unusual tooth alignment even if the results of orthodontic treatment are both morphologically and aesthetically successful.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2842.2000.00565.x
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  • 2
    Electronic Resource
    Electronic Resource
    The possibility of factors other than phytoalexin accumulation preventing fungal growth in the incompatible interactions of soybean with Phytophthora megasperma f. sp. glycinea (2002)
    Oxford, UK : Blackwell Science Ltd
    Plant pathology 51 (2002), S. 0 
    Details
    ISSN: 1365-3059
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Soybean (Glycine max) cv. Harosoy 63 is resistant to race 1 and susceptible to race 9 of Phytophthora megasperma f. sp. glycinea (Pmg). In detached primary leaves inoculated with zoospores, growth of race 1 was completely suppressed 16 h after inoculation, while race 9 was unaffected. The amount of the phytoalexin glyceollin that accumulated, however, was not significantly different in either the incompatible or compatible interaction 16 h after inoculation. At the circumference of the inoculated area, a slight accumulation of phytoalexin was observed only in the incompatible interaction 20 h or more after inoculation. Tolerance of race 9 to the phytoalexin was significantly higher than that of race 1 when the phytoalexin was added to agar. Moreover, race 9 degraded glyceollin faster than race 1. On leaves inoculated at separate points with either race, the lesion associated with race 9 never colonized areas inoculated with race 1. These results suggest that factor(s) other than the accumulation of phytoalexin in soybean tissue might cause cessation of growth of Pmg.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-3059.2002.00664.x
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  • 3
    Electronic Resource
    Electronic Resource
    Voltage shift phenomena in a heteroepitaxial BaTiO3 thin film capacitor (2002)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 91 (2002), S. 323-330 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Voltage shift phenomena of the hysteresis loop were characterized for a c-axis oriented heteroepitaxial BaTiO3 film by means of switching current measurements using various types of pulse sequences. During application of voltage, the hysteresis loop gradually shifted along the voltage axis according to the polarity of the voltage. Even after the application of voltage, while the top and bottom electrodes were short-circuited, the hysteresis loop continued to move. Under certain conditions, a part of the hysteresis loop shifted back, whereas the rest shifted forward. These results were explained, assuming that there is a nonswitching layer between the ferroelectric layer and the bottom electrode, and that the discontinuity of polarization can be compensated by injection of negative charges from the electrode. It was suggested that the nonswitching layer is possibly formed by relaxation of lattice misfit strain in the heteroepitaxial ferroelectric thin film. © 2002 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1426249
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  • 4
    Electronic Resource
    Electronic Resource
    Accumulation of CCR4-expressing CD4+ T cells and high concentration of its ligands (TARC and MDC) in bronchoalveolar lavage fluid of patients with eosinophilic pneumonia (2003)
    Oxford, UK : Munksgaard International Publishers
    Allergy 58 (2003), S. 0 
    Details
    ISSN: 1398-9995
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background: Th2 cells are thought to be involved in eosinophilic inflammation of the lung. CC chemokine receptor 4 (CCR4) has been identified as a specific receptor for both thymus and activation-regulated chemokine (TARC) and macrophage-derived chemokine (MDC), and is preferentially expressed on Th2 cells.Objective: Our aim was to evaluate the role of Th2 cells in the lung of patients with eosinophilic pneumonia (EP).Methods: The concentrations of TARC, MDC, and interleukin (IL)-5 were measured in bronchoalveolar lavage fluid (BALF) by ELISA. Proportion of CCR4-expressing CD4+ T cells (CCR4+ CD4+ T cells) was determined by flow cytometry.Results: TARC and MDC concentrations in BALF were higher in patients with EP than in normal subjects. The proportion of CCR4-expressing cells among CD4+ T cells was higher in BALF than in peripheral blood of patients with EP. There was a significant correlation between the number of CCR4+ CD4+ T cells and the levels of TARC, MDC, and IL-5 in BALF of patients with EP.Conclusions: Our data suggest that Th2 cells, which express CCR4 and its ligands (TARC and MDC), contribute to the pathogenesis of EP in the lung.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1034/j.1398-9995.2003.00149.x
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  • 5
    Electronic Resource
    Electronic Resource
    Incidence of peripheral blood eosinophilia and the threshold eosinophile count for indicating hypereosinophilia-associated diseases (2002)
    Oxford, UK : Munksgaard International Publishers
    Allergy 57 (2002), S. 0 
    Details
    ISSN: 1398-9995
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background: A definite threshold of the peripheral blood eosinophile count that indicates the presence of hypereosinophilia-associated diseases has not yet been determined.Methods: The threshold eosinophile count at which cases of hypereosinophilia-associated diseases (n = 25) can be differentiated from those of bronchial asthma (n = 101) was determined. Then, the incidences of eosinophile counts greater than 1.0 × 109/l or the threshold level, were studied by analysis of 43 805 samples sent to the laboratory, and the diseases associated with the increased counts were determined.Results: The eosinophile count in cases of hypereosinophilia-associated diseases and in those of bronchial asthma were 10.967 ± 1.680 × 109/l and 0.574 ± 0.045 × 109/l, respectively (P 〈 0.001); the threshold was 2.052 × 109/l. The percentages of samples with an eosinophile count of more than 1.0 × 109/l and 2.052 × 109/l were 0.6% and 0.1%, respectively; the latter comprised of 41 samples from 24 patients including eight with hypereosinophilia-associated diseases. The patients with hypereosinophilia-associated diseases had a significantly higher count, and a higher incidence of counts of more than 2.052 × 109/l, than others, including patients with malignancies and symptoms conventionally referred as “atopic diseases”.Conclusion: Hypereosinophilia-associated diseases are associated with a very high eosinophile count of more than 2.052 × 109/l, which was observed rarely.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1034/j.1398-9995.2002.23479.x
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  • 6
    Electronic Resource
    Electronic Resource
    Accumulation of superparamagnetic iron oxide and technetium-99m-galactosyl human serum albumin in a large regenerative nodule (2000)
    Springer
    European radiology 10 (2000), S. 1995-1995 
    Details
    ISSN: 1432-1084
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003300000517
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  • 7
    Electronic Resource
    Electronic Resource
    Proton magnetic resonance spectroscopy of a patient with Gerstmann-Straussler-Scheinker disease (2000)
    Springer
    Neuroradiology 42 (2000), S. 662-665 
    Details
    ISSN: 1432-1920
    Keywords: Key words Gerstmann-Straussler-Scheinker disease ; Magnetic resonance spectroscopy ; Single-photon emission computed tomography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A 23-year-old woman with Gerstmann-Straussler-Scheinker disease (GSS) was investigated by 1H-magnetic resonance spectroscopy (1H-MRS). She developed gait ataxic at 22 years. The diagnosis was confirmed by DNA analysis showing a proline-to-leucine point mutation at codon 102 of the prion protein. On 1H-MRS, she showed a remarkable reduction of the N-acetylaspartate/creatine ratio in the frontal lobe, cerebellar hemisphere and vermis and putamen. MRI revealed mild atrophy of the cerebellar hemispheres and vermis and cerebral cortex, but single-photon emission computed tomography (SPECT) with 99mHMPAO showed normal perfusion in the cerebellum. The imaging studies suggest that MRS might be superior to MRI or SPECT for detection of early neuronal degeneration.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002340000371
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  • 8
    Electronic Resource
    Electronic Resource
    Inhibitory effects of clozapine and other antipsychotic drugs on noradrenaline transporter in cultured bovine adrenal medullary cells (2000)
    Springer
    Psychopharmacology 149 (2000), S. 17-23 
    Details
    ISSN: 1432-2072
    Keywords: Key words Adrenal medullary cell ; Antipsychotic drug ; Clozapine ; [3H]Desipramine binding ; [3H]Noradrenaline uptake ; Noradrenaline transporter
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  The effects of clozapine and other antipsychotic drugs on noradrenaline (NA) transport were examined in cultured bovine adrenal medullary cells and in transfected Xenopus laevis oocytes expressing the bovine NA transporter. Incubation of adrenal medullary cells with clozapine (30–1000 ng/ml) inhibited desipramine (DMI)-sensitive uptake of [3H]NA in a concentration-dependent manner (IC50=110 ng/ml or 336 nM). Other antipsychotic drugs such as haloperidol, chlorpromazine, and risperidone also decreased [3H]NA uptake (IC50= 144, 220, and 210 ng/ml or 383, 690, and 512 nM, respectively). Eadie-Hofstee analysis showed that clozapine reduced Vmax of uptake of [3H]NA and increased Km. Furthermore, clozapine inhibited specific binding of [3H]DMI to plasma membranes isolated from bovine adrenal medulla (IC50=48 ng/ml or 146 nM). Scatchard plot analysis of [3H]DMI binding revealed that clozapine decreased both Bmax and Kd. Other antipsychotic drugs, including haloperidol, chlorpromazine, and risperidone, also reduced [3H]DMI binding to the membranes. In transfected Xenopus oocytes expressing the bovine NA transporter, clozapine inhibited [3H]NA uptake in a concentration-dependent manner similar to that observed in adrenal medullary cells. These results suggest that clozapine and haloperidol directly inhibit transport of NA by acting on the site of an NA transporter that influences both substrate transport and binding of tricyclic antidepressants.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002139900339
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  • 9
    Electronic Resource
    Electronic Resource
    Measurement of the cross-section and forward-backward charge asymmetry for the b and c-quark in $e^+e^-$ annihilation with inclusive muons at $\sqrt{s} = 58$ GeV (2000)
    Springer
    The European physical journal 18 (2000), S. 273-282 
    Details
    ISSN: 1434-6052
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract. We have studied inclusive muon events using all the data collected by the TOPAZ detector at $\sqrt{s}=58$ GeV with an integrated luminosity of 273pb $^{-1}$ . From 1328 inclusive muon events, we measured the ratio $R_{q\bar{q}}$ of the cross section for $q\bar{q}$ production to the total hadronic cross section and forward-backward asymmetry $A_{FB}^{q}$ for b and c quarks. The obtained results are $R_{b\bar{b}}=0.13\pm0.02(stat)\pm0.01(syst)$ , $R_{c\bar c}=0.36\pm0.05(stat)\pm0.05(syst)$ , $A_{FB}^{b}=-0.20\pm0.16(stat)\pm0.01(syst)$ and $A_{FB}^ c=-0.17\pm0.14(stat)\pm0.02(syst)$ , in fair agreement with a prediction of the standard model.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s100520000541
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  • 10
    Electronic Resource
    Electronic Resource
    Electrical activation of phosphorus-donors introduced in 6H-SiC by hot-implantation (2000)
    Springer
    Applied physics 71 (2000), S. 141-145 
    Details
    ISSN: 1432-0630
    Keywords: PACS: 61.72.Ww; 74.25.Fy; 74.62.Dh
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Abstract. Phosphorus ion (P+) implantations into 6H-SiC at room temperature (RT), 800 °C, and 1200 °C with mean concentrations of 1×1018–5×1019 /cm3 were performed to investigate the effects of hot-implantation on the electrical activation of P atoms. Improvement of the electrical activation of P atoms due to hot-implantation is found to depend on their implantation concentration, which can be divided into three regions. In the implantation with P in a low-concentration region (for example, 1×1018 /cm3), no significant difference in the carrier concentrations among the samples implanted at RT and elevated temperatures is observed after annealing above ≈1400 °C. In a medium-concentration region, the carrier concentration increases with implantation temperature. When P ions were implanted in a high-concentration region (for example, 5×1019 /cm3), the hot-implanted samples exhibit higher carrier concentration as compared with RT-implanted samples. Regarding hot-implantation, the carrier concentration in 800 °C-implanted samples is higher than that in the 1200 °C-implanted samples. This results can be interpreted as a degree of damage introduced by each implantation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003390050043
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