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  • 1
    Electronic Resource
    Electronic Resource
    Impact of erosion-transported overburden dump materials on water quality in Lake Cospuden evolved from a former open cast lignite mine south of Leipzig, Germany (2000)
    Springer
    Environmental geology 39 (2000), S. 683-688 
    Details
    ISSN: 1432-0495
    Keywords: Key words Geomorphology ; Soil chemistry ; Hydrochemical modelling ; Lignite mines
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Notes: Abstract  Acidification is the most common water quality problem in lakes created from previous open cast lignite mines. Aeration of aquifers and dump materials from mining activities causes pyrite oxidation. Pyrite oxidation products are stored in pore water, minerals and at the exchange complexes of the aquifers and dump sediments. Rainfall runoff transports sediments on the dump slope into the lakes. Elutriation of these sediments whithin the lakes releases either acid-producing or acid-neutralizing agents. At a test site south of Leipzig, the annual erosion rates were quantified by water erosion models (RUSLE, EROSION 2D, PEPP) and field measurements. They ranged from 300 up to 900 tons per hectare. Hydrogen ion equivalent release or binding at the sediment elutriation was computed from laboratory analysis of the pore-water quality, ion exchange complex and mineral composition of the sediment. Two of the three investigated sediments contained 3 mmol (eq) acidity per 100 g dry sediment and revealed saturation with respect to jarosite, jurbanite and gypsum. In the third sediment, 6 mmol (eq) alkalinity per 100 g dry sediment was obtained. The annual net acidity influx was calculated to be about 0.5 million mol (eq) for the lake of the test site.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002540050482
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    A methodology for analysis of complex sociotechnical processes (2001)
    Bradford : Emerald
    Business process management journal 7 (2001), S. 33-50 
    Details
    ISSN: 1355-2503
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Economics
    Notes: This article presents the design and application of a Modified Sociotechnical Systems (MoSTS) methodology for holistic analysis of complex technical processes. Successes and failures of process redesign initiatives have demonstrated the strong influence of human elements on outcomes. (Sociotechnical Systems) STS provides a foundation for structured analysis and redesign of complex processes which emphasizes human aspects in process redesign. The MoSTS methodology is developed from STS research and practice and applied to analyze a complex technical process in the research and development sector. MoSTS is shown to be an effective methodology to facilitate analysis for process redesign, particularly where human influences may have a significant impact on success. The article concludes with limitations and implications for process analysis based on the MoSTS methodology application.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1108/14637150110383926
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    A gene for autosomal dominant juvenile amyotrophic lateral sclerosis (ALS4 ) localizes to a 500-kb interval on chromosome 9q34 (2000)
    Springer
    Neurogenetics 3 (2000), S. 1-6 
    Details
    ISSN: 1364-6753
    Keywords: Key words Amyotrophic lateral sclerosis ; ALS4 locus ; Fine mapping of ALS4
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: ABSTRACT Amyotrophic lateral sclerosis (ALS) denotes a heterogeneous group of neurodegenerative disorders affecting upper and lower motor neurons. ALS4 is a juvenile-onset, autosomal dominant form of ALS that is characterized by slow progression, distal limb weakness and amyotrophy, and pyramidal signs associated with severe loss of motor neurons in the brain and spinal cord. The ALS4 locus was recently mapped by linkage analysis to a large genetic interval on chromosome 9q34. By undertaking extensive genetic linkage analysis, we have significantly refined the ALS4 locus to a critical interval of less than 3 cM, flanked by D9S149 and D9S1198. Previous physical mapping in this region has indicated that this critical interval spans approximately 500 kb. Seventeen putative transcripts have been localized within this interval including 7 characterized genes, 2 partially characterized genes, and 8 "anonymous" expressed sequence tags . These are therefore positional candidate genes for the ALS4 locus. We have also undertaken mutation analysis and genetic mapping to investigate and exclude candidate genes, including RING3L/ORFX and RALGDS , from a pathogenic role in ALS4.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/
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    Paper (German National Licenses)
    Fulltext
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