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  • 2000-2004  (4)
  • 1
    Electronic Resource
    Electronic Resource
    Salivary glands and noradrenergic transmission in diabetic rats (2002)
    Oxford, UK : Blackwell Science Ltd
    Autonomic & autacoid pharmacology 22 (2002), S. 0 
    Details
    ISSN: 1474-8673
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Chemistry and Pharmacology , Medicine
    Notes: 1 Type 2 diabetes is associated with diverse oral pathologies in which salivary flow reduction is one of the causes of these oral abnormalities. Scarce literature exists regarding noradrenergic transmission and adrenergic-induced salivary flow in submaxillary and parotid glands of type 2 diabetic rats. 2 We studied noradrenergic transmission as well as the secretory response to α1- and β-adrenoceptor stimulation in the parotid and submaxillary glands of type 2 diabetic rats. 3 Diabetic rats exhibited diminished neuronal uptake, release and endogenous content of noradrenaline (NE) in both salivary glands. Further, NE synthesis was also diminished accompanied by decreased tyrosine hydroxylase activity. Salivary flow responses to α1-(methoxamine) and β-(isoprenaline) adrenoceptor stimulation were reduced in the submaxillary as well as the parotid glands of diabetic rats. 4 Our results suggest that the reduction of noradrenergic transmission in the salivary glands of type 2 diabetic rats is in part responsible for the diminished salivary flow evoked by α1- and β-adrenergic stimulation. Reduced noradrenergic activity may contribute to the pathophysiology of oral abnormalities in diabetic patients.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1474-8673.2002.00243.x
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  • 2
    Electronic Resource
    Electronic Resource
    Influence of average size and interface passivation on the spectral emission of Si nanocrystals embedded in SiO2 (2002)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 91 (2002), S. 798-807 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The correlation between the structural (average size and density) and optoelectronic properties [band gap and photoluminescence (PL)] of Si nanocrystals embedded in SiO2 is among the essential factors in understanding their emission mechanism. This correlation has been difficult to establish in the past due to the lack of reliable methods for measuring the size distribution of nanocrystals from electron microscopy, mainly because of the insufficient contrast between Si and SiO2. With this aim, we have recently developed a successful method for imaging Si nanocrystals in SiO2 matrices. This is done by using high-resolution electron microscopy in conjunction with conventional electron microscopy in dark field conditions. Then, by varying the time of annealing in a large time scale we have been able to track the nucleation, pure growth, and ripening stages of the nanocrystal population. The nucleation and pure growth stages are almost completed after a few minutes of annealing time at 1100 °C in N2 and afterward the ensemble undergoes an asymptotic ripening process. In contrast, the PL intensity steadily increases and reaches saturation after 3–4 h of annealing at 1100 °C. Forming gas postannealing considerably enhances the PL intensity but only for samples annealed previously in less time than that needed for PL saturation. The effects of forming gas are reversible and do not modify the spectral shape of the PL emission. The PL intensity shows at all times an inverse correlation with the amount of Pb paramagnetic centers at the Si–SiO2 nanocrystal–matrix interfaces, which have been measured by electron spin resonance. Consequently, the Pb centers or other centers associated with them are interfacial nonradiative channels for recombination and the emission yield largely depends on the interface passivation. We have correlated as well the average size of the nanocrystals with their optical band gap and PL emission energy. The band gap and emission energy shift to the blue as the nanocrystal size shrinks, in agreement with models based on quantum confinement. As a main result, we have found that the Stokes shift is independent of the average size of nanocrystals and has a constant value of 0.26±0.03 eV, which is almost twice the energy of the Si–O vibration. This finding suggests that among the possible channels for radiative recombination, the dominant one for Si nanocrystals embedded in SiO2 is a fundamental transition spatially located at the Si–SiO2 interface with the assistance of a local Si–O vibration. © 2002 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1423768
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  • 3
    Electronic Resource
    Electronic Resource
    A 17-kDa allergen detected in pine nuts (2000)
    Copenhagen : Munksgaard International Publishers
    Allergy 55 (2000), S. 0 
    Details
    ISSN: 1398-9995
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background: Few cases of allergy to pine nuts have been described. We report a case of anaphylactic reaction to pine nuts. The patient needed to be treated in the emergency room due to a systemic reaction immediately after eating pine nuts. Methods: The patient was studied by prick tests and prick by prick tests. Specific IgE was measured by CAP and by SDS–PAGE/immunoblotting by a diffusion method. Results: The patient showed positive prick by prick tests to pine nuts (12 mm of maximum wheal diameter). Specific IgE was positive (0.79 kU/l). The patient's serum recognized several proteins by immunoblot. However, a 17-kDa allergen band was detected with high intensity. This protein was found to be sensitive to reducing agents, losing its IgE-binding properties after reduction. Conclusions: The patient presented an IgE-mediated reaction and detected a 17-kDa protein from pine nuts not previously described.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1034/j.1398-9995.2000.00291.x
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  • 4
    Electronic Resource
    Electronic Resource
    Uptake and metabolism of 6-benzyladenine in ventilated cultures of kiwifruit plants (2000)
    Springer
    Plant growth regulation 30 (2000), S. 209-214 
    Details
    ISSN: 1573-5087
    Keywords: Actinidia deliciosa ; benzyladenine ; cytokinins ; kiwifruit ; metabolism
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Abstract Uptake and metabolism of 6-benzyladenine (BA) werestudied in Actinidia deliciosa explants grown onventilated liquid Murashige and Skoog medium, usingcellulose plugs as explant support, after 0.5, 1, 2,8, 16, and 24h, 15 and 35 days of exposure to 14.8 kBqof 8-[14C] BA. Absorption of the BA is a rapidprocess and in the first half hour of culture 65% ofthe initial amount had disappeared from the medium.Exogenous BA was transformed into 7-β-D-glucopyranosyl-BA, 9-β-D-glucopyranosyl-BA, [9G]BA, 3-β-D-glucopyranosyl-BA, 9-β-D-ribofuranosyl-BA, [9R]BA, adenine, adenosine,and 5′-monophosphate of [9R]BA, [9R-5′P]BA. During thefirst 8h BA levels in the culture medium decreased,being converted into the active forms [9R]BA and[9R-5′P]BA. The excess of BA absorbed was inactivatedby glucosidation yielding [9G]BA. Ventilated culturesfavoured metabolization of active forms into inactivecompounds and this could be related to the lack ofhyperhydric shoots.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1006328819324
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