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  • 1
    Electronic Resource
    Electronic Resource
    Partial agonistic activity of labetalol, the arylethanolamine, on β3-adrenoceptors in the guinea-pig gastric fundus (2002)
    Oxford UK : Blackwell Science Ltd
    Autonomic & autacoid pharmacology 22 (2002), S. 0 
    Details
    ISSN: 1474-8673
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary 1 The agonistic and antagonistic effects of labetalol, the α1- and β-adrenoceptor antagonist, were studied on β3-adrenoceptors in the guinea-pig gastric fundus. 2 Labetalol caused a concentration-dependent relaxation with a pD2 value of 5.58 ± 0.09 and an intrinsic activity of 0.64 ± 0.06, which was not affected by pretreatment with both the selective β1-adrenoceptor antagonist, (±)-atenolol (100 μM), and the selective β2-adrenoceptor antagonist, (±)-butoxamine (100 μM). 3 However, the non-selective β1-, β2- and β3-adrenoceptor antagonist, (±)-bupranolol (3–30 μM), shifted the concentration–response curve of labetalol to the right (pA2 value=5.97 ± 0.08). 4 In the presence of (±)-atenolol (100 μM) and (±)-butoxamine (100 μM), relaxations to catecholamines [(−)-isoprenaline, (−)-noradrenaline and (−)-adrenaline], to the selective β3-adrenoceptor agonist, BRL37344, and to the non-conventional partial β3-adrenoceptor agonist, (±)-CGP12177A, were weakly antagonized by labetalol (10 μM). 5 These results indicate that labetalol, the arylethanolamine, acts as a partial agonist on β3-adrenoceptors in the guinea-pig gastric fundus.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1474-8673.2002.00239.x
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  • 2
    Electronic Resource
    Electronic Resource
    Correlation between periodontal status and biting ability in Chinese adult population (2003)
    Oxford, UK : Blackwell Science Ltd
    Journal of oral rehabilitation 30 (2003), S. 0 
    Details
    ISSN: 1365-2842
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: summary  This study investigated the relation between periodontal condition and biting ability in a Chinese population using the pressure-detecting sheet. A total of 142 subjects residing in Nanchang, Jiangxi province, China, participated in the study. The examination included probing pocket depth (PD), clinical attachment level (CAL), bleeding on probing and coronal caries teeth. Biting abilities per person, biting force, biting pressure and occlusal contact area were measured using the sheet. Number of teeth present showed positive correlation with biting force and occlusal contact area, but were negatively correlated with biting pressure. No significant correlation was observed between the mean PD, percentage of pocket ≥ 4 mm, bleeding index and any of biting abilities. The mean CAL showed a significantly negative correlation with biting force and occlusal contact area. Multiple stepwise regression analysis selected the number of teeth present, sex and age as the significant factors affecting the biting ability. However, no periodontal indices were picked up as the significantly contributing factor. There appears to be little effect of periodontal condition on biting ability. Ageing was selected as a contributing factor to reduction in the Chinese adults, but not in the Japanese population.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2842.2003.01012.x
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  • 3
    Electronic Resource
    Electronic Resource
    Accumulation of Butyltin and Phenyltin Compounds in Various Fish Species (2000)
    Springer
    Archives of environmental contamination and toxicology 39 (2000), S. 13-19 
    Details
    ISSN: 1432-0703
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Notes: Abstract Concentrations of organotins (OTs) were measured in the muscle of 11 species of fishes from the Port of Osaka and Yodo River, Japan. Tributytin (TBT) and triphenyltin (TPT) compounds were detected in the range of 0.011–0.182 mg/kg wet weight and 〈 0.001–0.130 mg/kg wet weight, respectively. Concentrations of TBT were higher than those of TPT in the muscle of fish. Concentrations of OTs in fish from sea areas were higher than those from rivers, and the ratios of TBT to total butyltins (BTs) in fish from sea areas were also higher than those from rivers. A similar trend was found for TPT. Logarithm of bioconcentration factor (BCF) of TBT in fish was in the range of 2.7–3.9. No sex differences in TBT and TPT concentrations in Japanese sea perch were observed, and the concentrations of TBT and TPT were not related to total length of fish. No correlation was also observed between the concentration of TBT or TPT and lipid content. The concentrations of BTs and phenyltins (PTs) in organs and tissues of three fish species were determined. TBT was higher concentration in liver, brain, and muscle of white croaker and yellowtail. The ratios of TBT to the total BTs were 30–40%, and the ratios of TPT to total PTs in these fishes were greater than 50% of the total PT concentrations.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002440010074
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  • 4
    Electronic Resource
    Electronic Resource
    Nonlinear Proximal Decomposition Method for Convex Programming (2000)
    Springer
    Journal of optimization theory and applications 106 (2000), S. 357-372 
    Details
    ISSN: 1573-2878
    Keywords: nonlinear proximal decomposition method ; Bregman functions ; convex programming
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Abstract In this paper, we propose a new decomposition method for solving convex programming problems with separable structure. The proposed method is based on the decomposition method proposed by Chen and Teboulle and the nonlinear proximal point algorithm using the Bregman function. An advantage of the proposed method is that, by a suitable choice of the Bregman function, each subproblem becomes essentially the unconstrained minimization of a finite-valued convex function. Under appropriate assumptions, the method is globally convergent to a solution of the problem.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1004655531273
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  • 5
    Electronic Resource
    Electronic Resource
    Activation Analysis of Several Species of Marine Invertebrates as Indicators of Environmental Conditions (2000)
    Springer
    Journal of radioanalytical and nuclear chemistry 244 (2000), S. 55-59 
    Details
    ISSN: 1588-2780
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Energy, Environment Protection, Nuclear Power Engineering
    Notes: Abstract Marine invertebrates are well known to accumulate trace metals from seawater, plankton, sea plants, and sediments. To test the usefulness of such organisms as a bio-indicator of environmental conditions, we have determined levels of trace elements in tissue of twelve species of marine invertebrates by photon and neutron activation analysis. Relatively higher concentration of elements were observed for Ni and Sn in mid-gut gland, for Cu and Zn in oyster tissues, for Se in swimming crabs, for Cu, Fe, and Se in gills of swimming crabs. Our results indicate that mid-gut gland of ear-shell will be useful as the indicator of environmental conditions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1006714820622
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  • 6
    Electronic Resource
    Electronic Resource
    Globally Convergent BFGS Method for Nonsmooth Convex Optimization1 (2000)
    Springer
    Journal of optimization theory and applications 104 (2000), S. 539-558 
    Details
    ISSN: 1573-2878
    Keywords: nonsmooth convex optimization ; Moreau–Yosida regularization ; strong convexity ; inexact function and gradient evaluations ; BFGS method
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Abstract We propose an implementable BFGS method for solving a nonsmooth convex optimization problem by converting the original objective function into a once continuously differentiable function by way of the Moreau–Yosida regularization. The proposed method makes use of approximate function and gradient values of the Moreau-Yosida regularization instead of the corresponding exact values. We prove the global convergence of the proposed method under the assumption of strong convexity of the objective function.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1004633524446
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