Library

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • 2000-2004  (4)
Material
Years
Year
Keywords
  • 1
    Electronic Resource
    Electronic Resource
    Oxford UK : Blackwell Science Ltd.
    Journal of neurochemistry 75 (2000), S. 0 
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract : The behavioral effects of cocaine are enhanced following constitutive deletion of the serotonin1B receptor. The neural substrates mediating the enhanced response to cocaine are unknown. The present studies determined whether basal dopamine dynamics or cocaine-evoked dopamine levels are altered in projection areas of mesostriatal or mesoaccumbens dopamine neurons following serotonin1B receptor deletion. Male wild-type and serotonin1B knockout mice were implanted with microdialysis guide cannulas aimed at the dorsal striatum or nucleus accumbens. The zero net flux method of quantitative microdialysis was used to quantify basal extracellular dopamine concentrations (DAext) and the extraction fraction of dopamine (Ed), which provides an index of dopamine uptake. Conventional microdialysis techniques were used to quantify cocaine (0, 5.0, and 20.0 mg/kg)-evoked dopamine overflow. Basal DAext and Ed did not differ in striatum of wild-type and knockout mice. Similarly, cocaine-stimulated dopamine overflow did not differ between genotype. The basal Ed did not differ in the nucleus accumbens of wild-type and knockout mice. However, DAext was significantly elevated in the nucleus accumbens of knockout mice. Cocaine-evoked dopamine overflow (nM) was also enhanced in the nucleus accumbens of knockout mice. However, the cocaine-induced increase in dopamine levels, relative to basal values, did not differ between genotype. These data demonstrate that deletion of the serotonin1B receptor is associated with increases in basal DAext in the nucleus accumbens. This increase is not associated with an alteration in Ed, suggesting increased basal dopamine release in these animals. It is hypothesized that these alterations in presynaptic neuronal activity are a compensatory response to constitutive deletion of the serotonin1B receptor and may contribute to the enhanced behavioral effects of psychostimulants observed in knockout mice.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 2
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 78 (2001), S. 105-107 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: We demonstrate a self-assembling method for growing semiconductor quantum dots into ordered lattices. The quantum dot nucleation and positioning into lattices was achieved using a periodic subsurface stressor lattice. Three different two-dimensional (2D) square lattices are demonstrated. The unit cell dimensions, orientation, and the number of quantum dots in the basis are tunable. We find that the 2D lattice can be replicated at periodic intervals along the growth direction to form a three-dimensional (3D) lattice of quantum dots. © 2001 American Institute of Physics.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 3
    Electronic Resource
    Electronic Resource
    Westerville, Ohio : American Ceramics Society
    Journal of the American Ceramic Society 87 (2004), S. 0 
    ISSN: 1551-2916
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: When fabricating multilayers with brittle constituents, a prevalent design strategy is to choose fabrication conditions and thermal expansion coefficients that impose in-plane compression on the brittle layers. In such designs, a small zone of out-of-plane tension is induced at the edges that can cause cracks to form and extend, especially along the midplane. The associated stresses and energy release rates have been analyzed, revealing a fail-safe criterion, attributed to the existence of a maximum possible energy release rate, Gmax. Equating this maximum to the toughness defines a fail-safe parameter expressing the influence of the layer thickness, the misfit stress, and the toughness. When fail-safe designs cannot be realized, thin interlayers can be interposed in a manner that diminishes Gmax, broadening accessibility. The roles of misfit stress and interlayer thickness in attaining this condition are derived.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Applied physics 71 (2000), S. 349-350 
    ISSN: 1432-0630
    Keywords: PACS: 81.05.Ea
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Abstract. Self-aligned GaN nanowire quasi-arrays were synthesized on MgO crystal through a simple gas reaction method. They were characterized by powder X-ray diffraction (XRD), field emission scanning electron microscopy (FE-SEM), energy-dispersive X-ray (EDX) spectroscopy and high-resolution transmission electron microscopy (HRTEM). FE-SEMimages showed that the product consisted of quasi-arrays of nanowires. XRD, EDX and HRTEM indicated that the nanowires were wurtzite GaN single crystals.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...