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  • 1
    Electronic Resource
    Electronic Resource
    Assessment of the carrier status by pedigree analysis in some families from India (2002)
    Oxford, UK : Blackwell Science Ltd
    Haemophilia 8 (2002), S. 0 
    Details
    ISSN: 1365-2516
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary.  Pedigree analysis is an important tool to assess the carrier status of the females in the families of haemophiliac patients. A study was conducted on 85 families, of which 75 were of haemophilia type A and 10 of haemophilia type B. The probability values of the females being carriers were calculated by the Bayesian method. The results revealed that 45 mothers were genetic obligate carriers and the remaining 40 probable, hence the transmission was of familial nature in 45 families, whereas the remaining 40 were categorized as isolated cases. The probability values of 425 females were calculated and a wide range of probability values ranging from 0.0295 to 1 was observed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2516.2002.00654.x
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  • 2
    Electronic Resource
    Electronic Resource
    Single-Base Oligodeoxyguanosine-Binding Proteins on Nonspecific Cytotoxic Cells: Identification of a New Class of Pattern-Recognition Receptors (2004)
    Oxford, UK; Malden, USA : Blackwell Science Ltd
    Scandinavian journal of immunology 60 (2004), S. 0 
    Details
    ISSN: 1365-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The present study was designed to identify a possible new class of pathogen-recognition proteins that bind single-base oligodeoxynucleotide (ODN) ligands. Binding by the teleost natural killer cell equivalent [referred to as nonspecific cytotoxic cells (NCC)] was compared with mammalian cells (mouse RAW264.7 cells and human THP-1 cells). The ODN analysed were composed of 20-mers of guanosine (dG20), adenosine (dA20), thymidine (dT20) or cytosine (dC20). Binding studies first determined the 50% saturation levels for NCC (1.25 µg/ml), RAW264.7 (0.2 µg/ml) and THP-1 (0.8 µg/ml). Binding by dG20 to all the three cell types was saturable. Ligand blots of NCC membrane lysates with biotinylated dG20 revealed two different major molecular weight species (16–18 and 29 kDa) of binding proteins. The 29-kDa protein was identified with the help of Western blot analysis using a polyclonal antibody specific to an NCC antimicrobial protein (ncamp-1). The membrane expression of the 29-kDa ncamp-1 was determined by the binding of surface-biotinylated NCC membrane proteins with digoxigenin dG20 followed by immunoprecipitation using anti-digoxigenin agarose beads. The 29 and 14–18 kDa NCC membrane proteins were cross-reactive using Western blot examination with a polyclonal anti-histone 1 antibody. Function studies revealed that dG20 activated a twofold upregulation of membrane binding by homologous dG20-biotin. dG20 also stimulated NCC-increased membrane expression of NCC receptor protein 1. Additional experiments were performed to determine the DNase sensitivity of the different ODN. dG20 appeared to be more resistant to DNase treatment, compared to dC20, dA20 and dT20. The single-base ODN-binding proteins may represent a new class of pattern-recognition receptors that are involved in innate anti-bacterial resistance mediated by NCC.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.0300-9475.2004.01455.x
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  • 3
    Electronic Resource
    Electronic Resource
    First report of Cis-AB inheritance from North India (2000)
    Springer
    International journal of anthropology 15 (2000), S. 137-146 
    Details
    ISSN: 1824-3096
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02442054
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  • 4
    Electronic Resource
    Electronic Resource
    Rotational bands in the doubly odd 130Cs nucleus (2001)
    Springer
    The European physical journal 11 (2001), S. 5-8 
    Details
    ISSN: 1434-601X
    Keywords: PACS. 21.10.Re Collective levels – 23.20.Lv γ transitions and level energies – 21.60.-n Nuclear-structure models and methods – 27.60.+j 90 ?A? 149
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract: The band structures built on the 5- isomeric state ( T 1/2 = 3.46 m) in the doubly odd 130Cs nucleus have been established up to I = 24? via the 124Sn(11B, 5n)130Cs reaction. The previously observed bands based on the πh 11/2⊗νh 11/2, πg 7/2⊗νh 11/2 and πd 5/2⊗νh 11/2 configurations and a positive-parity side band with multiple connections to the α = 0 signature partner of the yrast πh 11/2⊗νh 11/2 band have been extended to higher spins. A new band based on the πh 11/2⊗νg 7/2 configuration is observed. The yrast πh 11/2⊗νh 11/2 band exhibits anomalous signature splitting whose magnitude decreases up to spin 15 and then increases without restoring the normal signature splitting.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s100500170090
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    Paper (German National Licenses)
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