ISSN:
1072-8368
Source:
Nature Archives 1869 - 2009
Topics:
Biology
,
Medicine
Notes:
[Auszug] Here we report the first structure of a cocaine-degrading enzyme. The bacterial esterase, cocE, hydrolyzes pharmacologically active (−)-cocaine to a nonpsychoactive metabolite with a rate faster than any other reported cocaine esterase (kcat = 7.8 s−1 and KM = 640 nM). ...
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1038/nsb742
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