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  • 1
    Electronic Resource
    Electronic Resource
    Evaluation of diagonal earlobe crease as a marker of coronary artery disease: the use of this sign in pre-operative assessment* (2001)
    Oxford, UK : Blackwell Science Ltd
    Anaesthesia 56 (2001), S. 0 
    Details
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: In this study, we examined the usefulness of the earlobe crease sign as a marker of coronary artery disease in the pre-operative assessment of patients. We were interested in evaluating this sign for use in emergency patients. We investigated 530 patients, aged 〉 40 years, undergoing elective surgery. If the electrocardiogram was abnormal or the patient reported symptoms suggesting coronary artery disease, further cardiac examinations were performed. Patients who demonstrated evidence of coronary artery disease in the additional investigations or had a clear history of coronary artery disease were classified as the abnormal coronary group. Other patients with no history and/or normal investigations were classified as the normal coronary group. The assessment of earlobe crease sign was performed prior to anaesthesia, and the sensitivity, specificity and positive predictive value of this sign were calculated. We found that the sensitivity and specificity was high regardless of age, except for specificity in patients 〉 70 years old. The data suggest that the earlobe crease sign may be a useful marker for the presence of coronary artery disease in patients undergoing emergency operations in which little or no history and investigations are available. However, more work is required to assess the use of this sign in other ethnic groups.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2044.2001.02317.x
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  • 2
    Electronic Resource
    Electronic Resource
    Parathyroid hormone-related protein (PTH-rP)-producing lung cancer with psoas abscess-like metastasis and humoral hypercalcemia of malignancy (2000)
    Springer
    International journal of clinical oncology 5 (2000), S. 410-413 
    Details
    ISSN: 1437-7772
    Keywords: Key words Humoral hypercalcemia of malignancy (HHM) ; Lung cancer ; Psoas abscess-like metastasis ; Parathyroid hormone-related protein (PTH-rP)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We report a patient with lung cancer associated with psoas abscess-like metastasis and humoral hypercalcemia of malignancy (HHM). A 71-year-old man was hospitalized with exacerbating pain on the left-side of his back and thigh. A computed tomography (CT) scan of the abdomen demonstrated a tumor in the left iliopsoas muscle, first diagnosed as psoas abscess. A chest roentgenogram showed right-sided pleural effusion, and CT scan of the chest demonstrated a tumor in the right lower lobe of the lung. His serum calcium level was 12.8 mg/dl, and parathyroid hormone-related protein (PTH-rP) level was elevated, to 11.1 pmol/l. The patient died of progressive disease, and necropsy specimens were diagnosed as poorly differentiated squamous cell carcinoma. Immunohistochemical staining for PTH-rP was positive in the tumor cells, including the primary and the metastatic lesions. A review of this unusual tumor type is also presented.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
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