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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Acta neurochirurgica 142 (2000), S. 473-477 
    ISSN: 0942-0940
    Keywords: Keywords: Malignant triton tumour; nerve sheath tumour; rhabdomyosarcoma; ventricle; neurofibromatosis.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary ¶ The authors present the clinical and pathological features of a malignant triton tumour (MTT) in the lateral ventricle with neurofibromatosis type 1. A 57 year-old man presented with disorientation and memory disturbance. A Computed tomographic scan and magnetic resonance imaging studies revealed an enhancing lesion in the left lateral ventricle. A parieto-occipital transcallosal approach was taken and resection of the lesion was performed. The operative findings suggested that the tumour arose from the perivascular nerves. The final pathological diagnosis was a MTT. This is the first case of an intraventricular MTT. Aggressive treatment including radical surgery combined with radiochemotherapy is recommended for a MTT of the central nervous system.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    Journal of the European Academy of Dermatology and Venereology 16 (2002), S. 0 
    ISSN: 1468-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: A 59-year-old Japanese man presented with a slightly elevated, pruritic, erythematous plaque on his left buttock measuring 5 × 5 cm in diameter. The man had a history of chromomycosis, dating 6 years prior to the current consultation, for which he had been treated with oral terbinafine. Diagnosis of a recurrence of chromomycosis of the skin due to infection by Foncecaea pedrosoi was made after careful analysis of the clinical features, skin biopsy, KOH mounts, and fungal culture results. We administered topical heat thereapy followed by treatment with CO2 laser to eradicate the unresponsive remnants of the lesion. The operative site re-epithelized within 10 weeks, and 1 year after the treatment there was no evidence of recurrence. For a recalcitrant case of chromomycosis, as in this case, the use of CO2 laser combined with topical heat therapy may be a new therapeutic modality.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1365-2516
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary.  Haemostatic management of intraoral bleeding was investigated in patients with congenital α2-plasmin inhibitor (α2-PI) deficiency or congenital plasminogen activator inhibitor- 1 (PAI-1) deficiency. When extracting teeth from patients with congenital α2-PI deficiency, we advocate that 7.5–10 mg kg−1 of tranexamic acid be administered orally every 6 h, starting 3 h before surgery and continuing for about 7 days. For the treatment of continuous bleeding, such as post-extraction bleeding, 20 mg kg−1 of tranexamic acid should be administered intravenously, and after achieving local haemostasis 7.5 mg kg−1 of tranexamic acid should be administered orally every 6 h for several days. In addition, when treating haematoma caused by labial or gingival laceration or buccal or mandibular contusion, haemostasis should be achieved by administering 7.5–10 mg kg−1 of tranexamic acid every 6 h. Tranexamic acid can also be used for haemostatic management of intraoral bleeding in patients with congenital PAI-1 deficiency, but is less effective when compared with use in patients with congenital α2-PI deficiency. Continuous infusion of 1.5 mg kg−1 h−1 of tranexamic acid is necessary for impacted tooth extraction requiring gingival incision or removal of local bone.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    Histopathology 37 (2000), S. 0 
    ISSN: 1365-2559
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    Journal of oral rehabilitation 31 (2004), S. 0 
    ISSN: 1365-2842
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: summary  The purpose of this study was to examine the efficacy of experimentally developed high purity glyceryl mono-methacrylate (GM) as a dentine primer and to evaluate the possibility of allergic reaction. The efficacy of experimental dentine primers was evaluated by measuring the polymerization contraction gap width and the tensile bond strength. Allergic reaction was evaluated by the guinea-pig maximization test. The skin reaction was evaluated according to the criteria of the International Contact Dermatitis Research Group. Contraction gap formation was completely prevented and the tensile bond strength was not significantly affected by priming with GM on high-purity GM. The allergic response decreased when high-purity GM was employed as the challenger. It was concluded that the clinical use of the high-purity GM is beneficial as the delayed allergic reaction could be avoided with no detrimental effect on the dentine bonding.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    Journal of oral rehabilitation 30 (2003), S. 0 
    ISSN: 1365-2842
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: summary  Of the cytochrome P450 (CYP) family of carcinogen-activating enzymes, CYP3A is the major form found in human livers. The purpose of this study was to investigate the cytotoxic effects of dental resin monomers after being metabolized by CYP3A4 and CYP3A7, using a colony formation assay and a neutral red assay. Specimen wells were plated with transfected cells derived from the Chinese hamster lung at 100 cells well−1. The experimental group consisted of CYP-producing 3A4-10 and 3A7-40 cells, while the control group consisted of non-CYP-producing CR-119 cells. Bisphenol A (BPA) and bisphenol A glycidyl methacrylate (Bis-GMA) and a positive control (Aflatoxine Bl) were added separately to each well and cultured for 7 days. After cultivation, the number of the colonies was counted and IC50 values were determined. The data were statistically analysed by a Student's t-test. The resultant of IC50 values indicated that the monomers were not metabolically activated by CYP3A4 or CYP3A7 as compared with the control (P 〈 0·05). We also confirmed that these monomers act neither as activators nor as inhibitors of CYP3A4 and CYP3A7.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 89 (2001), S. 5282-5287 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Transparent optical nonlinear crystallized glasses with the composition of 25La2O3 25B2O3 50GeO2, stoichiometric to ferroelectric stillwellite-type LaBGeO5 crystalline phase, have been prepared by a two-step heat-treatment (first heat treatment: T1=670 °C, t1=10 h, second heat-treatment: T2, t2), and their second harmonic (SH) intensities have been examined using the Maker fringe method. The samples obtained by heat treatments at T2=720∼725 °C for t2=3 h show only surface crystallization and exhibit clear and fine (narrow) fringe patterns. The samples heat treated at T2=740 and 750 °C exhibit relatively strong SH intensities, but the fringe patterns in such samples are broad. It is proposed that SH waves generated from surface LaBGeO5 crystalline layers scatter at LaBGeO5 crystals formed in the interior of glass, causing the disappearance of fine fringe patterns. © 2001 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 87 (2000), S. 3707-3710 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The influence of oxygen pressure on epitaxial quality of La0.3Sr1.7AlTaO6 (LSAT) films deposited by laser ablation on SrTiO3(100), LaAlO3(100), and MgO(100) substrates has been investigated. X-ray diffraction shows only (00l) peaks in the oxygen pressure range from 10−3 to 500 mTorr. However, the crystallinity of LSAT films is found to be sensitive to oxygen pressure and dependent on substrates. LSAT films on SrTiO3 have the narrowest full width at half maximum (FWHM) of 0.05° at 300 mTorr. The films on LaAlO3 exhibit a FWHM of 0.3° at 50–100 mTorr. On MgO substrate, significant improvement of crystallinity is achieved at 200–300 mTorr, but rocking curves give an FWHM of 0.70°–1.00° due to the large lattice mismatch between LSAT and MgO. Atomic force microscopy analyses demonstrate smooth LSAT surfaces without identified grains. Reflection high-energy electron diffraction studies suggest a two-dimensional growth mode for LSAT films on SrTiO3 and LaAlO3 and a three-dimensional growth mode for LSAT films on MgO. Cross-sectional high-resolution electron micrographs indicate that LSAT films on SrTiO3 and LaAlO3 have defect-free epitaxial structure and atomically flat interfaces. An 80 Å thick intermediate layer with partially disordering is observed between LSAT films and MgO substrates. © 2000 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: We previously demonstrated the circadian variation of water-immersion restraint stress (WRS)-induced gastric mucosal lesions in rats.〈section xml:id="abs1-2"〉〈title type="main"〉Aim:To investigate the roles of melatonin and prostaglandin in the gastric mucosa in circadian modulation of WRS.〈section xml:id="abs1-3"〉〈title type="main"〉Methods:Fasted rats were subjected to 4-h WRS during both the diurnal and nocturnal phases of a light/dark cycle. Mucosal lesions, serum melatonin concentrations, mucosal generation of prostaglandin E2 (PGE2) and mucosal gene expressions of cyclooxygenase (COX)-1 and -2 were evaluated.〈section xml:id="abs1-4"〉〈title type="main"〉Results:Lesion area after 4-h stress during the dark phase was significantly smaller than that in light-phase controls. Serum melatonin concentration in control rats during the light phase was significantly increased 4 h after WRS, but PGE2 generation was decreased by 48% as compared to that in intact mucosa before stress. In the dark phase, melatonin concentration after 4-h WRS was significantly depressed as compared with the control level at the corresponding time. PGE2 concentrations after 4-h WRS in the dark phase were not decreased compared with the control level at the corresponding time, although PGE2 level was significantly lower than that in light-phase controls. Expression of COX-1 and COX-2 mRNA was detected after exposure to stress in both the light and dark phases.〈section xml:id="abs1-5"〉〈title type="main"〉Conclusion:These results suggest that circadian rhythm has an important role in the formation of stress-induced gastric mucosal lesions in rats. The circadian rhythm of melatonin responses and PGE2 generation may contribute to nocturnal/diurnal rhythmicity of gastric mucosal defences between day and night.
    Type of Medium: Electronic Resource
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