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  • 2000-2004  (4)
  • 1
    Digitale Medien
    Digitale Medien
    Large low-field magnetoresistance of phase-separated single-crystalline Pr0.7Pb0.3MnO3 (2002)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 80 (2002), S. 3367-3369 
    Details
    ISSN: 1077-3118
    Quelle: AIP Digital Archive
    Thema: Physik
    Notizen: A large low-field magnetoresistance (MR) slightly above the metal–insulator transition temperature (234 K) was observed in single-crystalline Pr0.7Pb0.3MnO3. Combining the temperature dependence of magnetization, resistance, and electron spin resonance spectra, it was suggested that phase separation occurs above the Curie temperature; ferromagnetic metallic clusters imbedding in the insulating paramagnetic matrix, and spin-polarized electron tunneling between isolated ferromagnetic clusters should be responsible for the large low-field MR observed. Undoubtedly, this observation opens a window to explore large low-field MR at high temperature, which is very important for the practical application of colossal MR effect. © 2002 American Institute of Physics.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1063/1.1477940
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  • 2
    Digitale Medien
    Digitale Medien
    Dissociation of function between the dorsal and the ventral hippocampus in spatial learning abilities of the rat: a within-subject, within-task comparison of reference and working spatial memory (2004)
    Oxford, UK : Blackwell Science Ltd
    European journal of neuroscience 19 (2004), S. 0 
    Details
    ISSN: 1460-9568
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: Lesions restricted to the dorsal, but not the ventral, hippocampus severely impair the formation of spatial memory. This dissociation was first demonstrated using the water maze task. The present study investigated whether the dorsal and the ventral hippocampus are involved differentially in spatial reference and spatial working memory using a four-baited/four-unbaited version of the eight-arm radial maze task. This test allows the concurrent evaluation of reference and working memory with respect to the same set of spatial cues, and thereby enables a within-subjects within-task comparison between the two forms of memory functions. Rats with N-methyl-d-aspartic acid-induced excitotoxic lesions of the dorsal hippocampus, ventral hippocampus or both were compared with sham and unoperated controls. We showed that dorsal lesions were as effective as complete lesions in severely disrupting both reference and working spatial memory, whereas rats with ventral lesions performed at a level comparable with controls. These results lend further support to the existence of a functional dissociation between the dorsal and the ventral hippocampus, with the former being preferentially involved in spatial learning.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.0953-816X.2004.03170.x
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  • 3
    Digitale Medien
    Digitale Medien
    Targeted destabilization of HY5 during light-regulated development of Arabidopsis (2000)
    [s.l.] : Macmillian Magazines Ltd.
    Nature 405 (2000), S. 462-466 
    Details
    ISSN: 1476-4687
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Chemie und Pharmazie , Medizin , Allgemeine Naturwissenschaft , Physik
    Notizen: [Auszug] Arabidopsis seedlings display contrasting developmental patterns depending on the ambient light. Seedlings grown in the light develop photomorphogenically, characterized by short hypocotyls and expanded green cotyledons. In contrast, seedlings grown in darkness become etiolated, with elongated ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/35013076
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  • 4
    Digitale Medien
    Digitale Medien
    Detection of Hepatitis B Virus Surface Antigen Mutants in Paraffin-Embedded Hepatocellular Carcinoma Tissues (2000)
    Springer
    Virus genes 20 (2000), S. 263-267 
    Details
    ISSN: 1572-994X
    Schlagwort(e): hepatitis B virus ; hepatitis B virus surface antigen ; viral DNA isolation ; mutations ; hepatocellular carcinoma ; paraffin-embedded tissue
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract The antigenic “a” determinant of the human hepatitis B virus surface antigen (HBsAg) is highly conserved and involved in inducing neutralizing antibody. Mutations on this determinant have been associated with the hepatitis B virus (HBV) escape from vaccination but are also found in chronic HBV carriers, but their involvement in liver diseases including hepatocellular carcinoma (HCC) is unclear. To investigate the possible liver disease-associated role of HBsAg mutants, their incidence was analyzed in 11 paraffin embedded HCC tissues using an improved DNA extraction method. Mutations on the “a” determinant (Thr126Ser, Gly145Arg, a double mutant Thr126Ser/Gln129Asn, Met133Leu and Thr140Ile) were identified in 5 samples while the wild type sequence was found in 2 others. Future characterization of these HCC-associated HBsAg mutants should provide new insights on their role in the pathogenesis of HCC.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1023/A:1008100930584
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