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  • 1995-1999  (1)
  • 1990-1994  (3)
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  • 1
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary Chronic graft-versus-host disease after bone marrow transplantation presents, in a few cases, as mild to severe scleroderma-like changes. Patients with chronic graft-versus-host disease with and without sclerodermatous skin changes were analysed for antinuclear autoantibodies (ANA) and antinucleolar autoantibodies (ANoA) and the results correlated with disease symptoms and histocompatibility locus antigen (HLA) pattern. Nineteen patients with chronic graft-versus-host disease and scleroderma-like skin changes. 18 with chronic graft-versus-host diseae without scleroderma. and 17 controls on immunosuppressive treatment were screened for ANA and ANoA using enzyme-linked immunosorbent assay, immunodiffusion and immunoblot techniques. Four patients with severe scleroderma had antibodies to topoisomerase I. two had antibodies against PM-Scl. both characteristic serological findings in idiopathic systemic scleroderma. One patient had La/SSB antibodies and, in three cases, antibodies to the nucleolar antigen C23 (nucleolin) could be identified. A possible correlation between antinucleolin antibodies and disease activity was observed. HLA-Al. -B1. and -B2 were found significantly more often in patients with scleroderma-like symptoms in comparison to patients without scleroderma-like symptoms. Chronic graft-versus-host disease with seleroderma-like manifestations can be associated with the occurrence of ANA specific for idiopathic scleroderma. The development of seleroderma after bone marrow transplantation might have a HLA-linked genetic background.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1434-601X
    Keywords: 20.00 ; 25.85.Ec
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The mass and nuclear charge distributions of fission fragments from229Th(nth, f) have been measured at several kinetic energies with the mass spectrometer Lohengrin (ILL-Grenoble). The average proton e-o effect, which reaches 41%, induces large oscillations in the parameters of the isotopic charge distribution. A comparison of the data from different fissile nuclei shows the importance of the last stage of the process for intrinsic excitations.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1434-601X
    Keywords: 23.40
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The half-lives of very neutron rich isotopes of Ni and Cu have been measured. The isotopes are produced in very asymmetric thermal fission of235U and239Pu at the I.L.L. high flux reactor. They are separated by means of the Lohengrin spectrometer. They are identified with aΔE-E ionization chamber and implanted in one of the 8 Si planar detectors where theβ-particles are also detected. The time correlations between the implantation and the detection ofβ-particles provide the half-life. The values obtained are compared to current theoretical predictions.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1434-601X
    Keywords: 21.10.Dr ; 27.60.+j
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Theβ-decay energy of the neutron-rich isotopes148Ba,148La and151Pr has been measured at the Institute Laue-Langevin (ILL). The148Ba- and148La-nuclei were produced using a high-temperature ion source at the OSTIS separator of this institute, whereas samples of151Pr were obtained from the thermal fission of239Pu, used as a target in the mass separator LOHENGRIN. At both instruments,βγ-coincidences were measured with a plastic scintillator telescope and a Ge(I)-detector, together withβ-singles andγ-singles spectra. Theβ-spectra emitted in coincidence with 44γ-lines in the decay of these nuclei have been evaluated. From their endpoint energies, the followingQ β -values have been obtained:Q β (148Ba)=5115±60keV;Q β (148La)=7255±55 keV;Q β (151Pr)=4170±75 keV. Using these results, the nuclear massesA of these nuclei can be calculated with a relative error ΔA/A≃5·10−7. In addition, the two-neutron separation energies and the mass excesses have been derived; the results are compared with recent predictions of theoretical mass calculations.
    Type of Medium: Electronic Resource
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