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  • 1
    Electronic Resource
    Electronic Resource
    Application of 6 MeV/n heavy-ion beams to biophysical experiments (abstract)a) : Proceedings of the 6th international conference on ion sources (1996)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 67 (1996), S. 1374-1374 
    Details
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: A new facility using 6 MeV/n heavy-ion beams is described along with preliminary results of its applications to biophysical investigations. The beams are obtained at the terminal of the injector linac installed in the heavy-ion medical accelerator in Chiba. Various ion species (He–Xe) having different charge states are accelerated to the same velocity, which is suitable for comparing the charge effects of heavy ions. An attempt has been made for investigations of the track structure by using pBR322 plasmid DNA and spores as targets. Newly constructed equipment with the molecular beam source (H2O) placed on this beam line is also described. © 1996 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1146672
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  • 2
    Electronic Resource
    Electronic Resource
    Application of 6 MeV/n heavy-ion beams to biophysical experiments (1996)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 67 (1996), S. 2000-2004 
    Details
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: A new accelerator facility and two irradiation methods using 6 MeV/n heavy-ion beams are described along with preliminary results concerning their applications to biophysical investigations. The beams are obtained from the injector linac installed at the Heavy Ion Medical Accelerator in Chiba. Various ion species (He–Xe) having different charge states are accelerated to the same velocity, which is suitable for comparing the charge effects of heavy ions in the high linear energy transfer region. An attempt has been made to test the usefulness of the apparatus for studying track structure by using pBR322 plasmid DNA and spores as targets in vacuum. Newly constructed equipment with a molecular-beam source (water vapor) placed on this beam line is also described. © 1996 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1146958
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  • 3
    Electronic Resource
    Electronic Resource
    Specific lattice location of Zn in CdTe determined by ion-channeling methods (1988)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 52 (1988), S. 200-202 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The specific lattice location of Zn in CdTe single crystals has been investigated by ion-channeling methods combined with particle-induced x-ray emission. Observing the asymmetry effects of channeling dips around the [110] axis and analyzing the asymmetry factors for host atoms and doped Zn atoms, it is revealed that almost all Zn atoms occupy the Cd sublattice sites, and Zn-doped CdTe crystals grown by vertical Bridgman methods appear to be almost completely free from the segregation of doped Zn atoms.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.99653
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  • 4
    Electronic Resource
    Electronic Resource
    Low-threshold 1.55-μm InGaAsP/InP buried heterostructure distributed feedback lasers (1987)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 51 (1987), S. 273-275 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: An extremely low-threshold current of 6 mA in cw mode at 22 °C was achieved in 1.55-μm InGaAsP/InP buried heterostructure distributed feedback lasers with a first-order grating and a normal cavity length of 300 μm. These lasers exhibited an average differential efficiency of 30% total at 4 mW without any coating on the facets, and a T0 (25–70 °C) value of 55 K. A spectral linewidth as low as 8 MHz at cw mode was obtained. The lasers showed high-speed pulse modulation response to 2.4 Gb/s (NRZ).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.98471
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  • 5
    Electronic Resource
    Electronic Resource
    Annealing behavior of bound exciton lines in high quality CdTe (1988)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 53 (1988), S. 1524-1526 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Annealing behavior of shallow donor-bound and acceptor-bound exciton lines in CdTe crystals grown by the Bridgman method was investigated by high-resoluton photoluminescence measurements at 4.2 K. The intensity of the neutral acceptor-bound exciton line (A0X) at 1.5896 eV, which was commonly observed in p-type CdTe, drastically decreased by annealing under Cd saturated atmosphere. By further subsequent annealing under Te saturated atmosphere, the A0X line recovered again. On the other hand, the intensity of the neutral donor-bound exciton line increased by annealing under Cd saturated atmosphere and decreased by the further annealing under Te saturated atmosphere. It was found that this change in the photoluminescence lines by the annealing process was reversible. These results strongly suggest that the A0X line at 1.5896 eV can be ascribed to the recombination of excitons trapped at Cd-vacancy/donor-impurity complexes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.99945
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  • 6
    Electronic Resource
    Electronic Resource
    Mitochondrial Function in Normal and Genetically Altered Cells and Tissues (1988)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 550 (1988), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1988.tb35350.x
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  • 7
    Electronic Resource
    Electronic Resource
    Electrocatalytic aspects of iron phthalocyanine and its .mu.-oxo derivatives dispersed on high surface area carbon (1987)
    s.l. : American Chemical Society
    The @journal of physical chemistry 〈Washington, DC〉 91 (1987), S. 3799-3807 
    Details
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/j100298a016
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  • 8
    Electronic Resource
    Electronic Resource
    Serum Level of Interleukin-4 in Patients with Perennial Allergic Rhinitis During Allergen-Specific Immunotherapy (1996)
    Oxford, U.K. and Cambridge, USA : Blackwell Science Ltd
    Scandinavian journal of immunology 43 (1996), S. 0 
    Details
    ISSN: 1365-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Interleukin-4 (IL-4) may play a central role in the IgE synthesis system, the development of Th-2-like cells, and co-ordination as well as the persistence of airway inflammatory process in allergic disorders. Therefore, IL-4 plays a key role in airway allergic disorders. This study aimed at investigating the serum concentrations of IL-4 in patients with perennial allergic rhinitis, with special reference to the possible changes and the clinical relevance following long-term immunotherapy. The study has demonstrated that the serum level of IL-4 in allergic rhinitis patients before immunotherapy is significantly higher than that in non-atopic individuals. However, the serum IL-4 level in allergic rhinitis patients did not decrease following anti-allergic medications but significantly decreased following immunotherapy. The percentage decrease in IL-4 was correlated significantly with the percentage decrease in specific IgE antibodies following long-term immunotherapy. Immunotherapy also significantly decreased specific IgE antibodies, but this reduction in specific IgE antibodies was not significantly correlated with the clinical improvement. In contrast, the percentage decrease in serum IL-4 was significantly correlated with the percentage decrease in symptomatic scores. The authors interpret these data to mean that immunotherapy alters T-cell cytokine profiles in the long-term, and a decline of IL-4 following immunotherapy could modulate not only production of specific IgE antibodies but also inflammatory cellular events, leading to symptomatic relief in allergic rhinitis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-3083.1996.d01-269.x
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  • 9
    Electronic Resource
    Electronic Resource
    High frequency permeability of patterned spin valve type thin films (1999)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 85 (1999), S. 5852-5854 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The dynamic response of spin valve films were studied and compared to NiFe/CoFe bilayer and NiFe single layer films by measuring their high frequency permeability spectra on sheet and patterned samples. It was found that the high frequency response of these thin films were affected only by the ferromagnetic resonance and the behavior was well described by the calculated Landau–Lifshitz–Gilbert permeability. The resonance frequency of spin valve films was strongly influenced by the interaction field from the pinned layer. Decreasing interlayer thickness of Cu resulted in an increase of the interaction field, which shifted the resonance frequency to higher frequencies while reducing the initial permeability. The shape anisotropy, which was increased by decreasing pattern size, also shifted the films resonance frequency to higher values accompanied by lowered initial permeabilities. Regarding their dynamic response, spin valve films were found to be suitable for ultrahigh recording densities, when the effective anisotropy was sufficiently large. © 1999 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.369938
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  • 10
    Electronic Resource
    Electronic Resource
    Serum Level of Soluble Interleukin-2 Receptor in Patients with Seasonal Allergic Rhinitis (1997)
    Oxford, U.K. and Cambridge, USA : Blackwell Science Ltd
    Scandinavian journal of immunology 45 (1997), S. 0 
    Details
    ISSN: 1365-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The rate of release of the soluble form of interleukin-2 receptor (soluble IL-2R) reflects T cell activation in vivo. Since T lymphocytes play a central role in respiratory allergic disorders, the measurement of serum levels of soluble IL-2R may be useful in analysing the disease state of allergic disorders. The study has aimed at investigating the seasonal changes in serum soluble IL-2R in 81 patients with seasonal allergic rhinitis due to Japanese cedar pollens, with special reference to the effect of anti-allergic pharmacotherapy and immunotherapy. Serum samples were obtained twice from each patient, before and during the pollen season, and all the serum samples were simultaneously used for determination of soluble IL-2R and cedar pollen-specific immunoglobin E (IgE). Seasonal elevation in soluble IL-2R was not associated with the good clinical outcome but was associated with the poor clinical outcome, irrespective of pharmacotherapy or immunotherapy. Additionally, successful immunotherapy suppressed seasonal elevation of serum soluble IL-2R more strongly than successful pharmacotherapy, and seasonal increase rates in soluble IL-2R were inversely correlated with the duration of immunotherapy. Seasonal increase rates in soluble IL-2R were significantly correlated with seasonal increase rates in specific IgE in both the medication group and the immunotherapy patients. These results may suggest that seasonal changes in serum soluble IL-2R may serve as an indicator for clinical outcome of seasonal allergic rhinitis, that the magnitude of T cell activation could affect specific IgE production, and that T cell activation could be gradually modulated as immunotherapy proceeds. In conclusion, seasonal changes in serum soluble IL-2R may serve as an objective indicator for clinical outcome of seasonal allergic rhinitis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-3083.1997.d01-392.x
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