ISSN:
1432-0711
Keywords:
Key words: Alpha-fetoprotein (AFP)
;
Premature rupture of membranes (PROM)
;
Monoclonal antibody
;
Kit
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract. A kit using mouse monolconal antibody against human alpha-fetoprotein (anti-AFP kit) has been developed. Cervical secretion (n=34) and vaginal fluid (n=15) was obtained from 30 pregnant volunteers. All 31 specimens obtained from women with intact membranes tested negative while all 18 specimens from women with premature rupture of membranes (PROM) tested positive. The newly developed kit allowed rapid and accurate diagnosis. We compared the kit results with those obtained by pH determination (nitrazine, bromthymol blue test) and measurement of AFP concentrations by enzyme-linked immunoassay (EIA).
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00634709
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