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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Anaesthesia 51 (1996), S. 0 
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Spontaneous movement following injection of propofol at induction was studied in 303 patients. Two hundred patients were Caucasians and 103 were Asians. In a pilot study carried out prior to the main study, 26% of the Asians moved at induction as compared with 6% of the Caucasians. The patients were studied in relation to a number of variables; age, sex, weight, height, race, smoker/non smoker, vegetarian/non vegetarian, alcohol consumption, premedication, use of fentanyl at induction and dose of propofol. When race was included as the sole variable there was a marginal but not significant difference between the two groups in terms of movement (p = 0.06). However, when the other recorded variables were taken into account, race was not included as a predictor of whether or not the patient moved. The best model for predicting whether the patients moved or not combines the variables weight and dose of propofol. Patients were more likely to move if they were lighter and the dose of propofol used at induction was higher.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Anaesthesia 51 (1996), S. 0 
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: One hundred patients undergoing breast lump excision using a standard anaesthetic technique in the Day Care Unit were randomly divided into five groups. Groups A and B received either saline or diclofenac in a double blinded, fashion before and at the end of the procedure, with both groups receiving 10 ml of 0.5% bupivacaine infiltration at the end. Groups C and D also received saline or diclofenac before and after surgery but had no bupivacaine infiltration at the end. Group E did not receive any injections but had bupivacaine infiltration at the end of surgery. In the postoperative period, pain was assessed by a visual analogue scale at 30 min intervals until discharge. All patients were requested to complete a pain relief questionnaire over the 48 h following surgery. There were highly significant differences between those who received bupivcaine and those who did not in the visual analogue scale scores at 30min (p 〈 0.001), 60 min (p 〈 0.001), 120 min postoperatively (p = 0.02) and at discharge (p = 0.03). Pain scores were lower in those who received bupivacaine and they were less likely to request rescue medication, although this did not reach significance (p = 0.07). There were significant differences between the groups who received bupivacaine and diclofenac injection and those who received bupivacaine alone, for visual analogue scale scores at 60 min following surgery (p = 0.05) and at 48 h (p = 0.002). Pain relief was better in those patients who received both bupivacaine and diclofenac injection. Although not significant (p = 0.22). fewer patients required rescue medication when diclofenac was given before surgery (10%) rather than after surgery (22.5%). Fewer patients had a fair amount or a great deal of pain in the 48 h following surgery when diclofenac was injected before (7.5%) rather than after surgery (12.5%). The mean number of oral analgesics taken in the 48 h after surgery was also lower in those patients who had the diclofenac before the surgery rather than after.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-0932
    Keywords: Lumbar spine ; Spinal motion ; Normal population ; Low back pain population ; Diagnosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract There are few objective means by which disability caused by low back pain (LBP) can be quantified. The purpose of this study was to investigate the usefulness of motion measurements in the assessment of LBP. The motion characteristics of 138 LBP subjects were investigated, and the data compared with a previously published database of normal subjects. Values of range of motion and angular velocity were obtained for all subjects in each plane of motion. Analysis of these motion characteristics demonstrated significant differences (P 〈 0.0001) between the two populations; however both populations demonstrated considerable intersubject variation. Multiple regression analysis revealed that some of the variance in the LBP population was attributable to the underlying diagnosis. Patients with a spondylolisthesis tended to be hypermobile whilst those with spinal stenosis, disc prolapse or degenerative disc disease tended to be hypomobile. All diagnostic groups showed impairments in their velocity characteristics.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Clinical autonomic research 6 (1996), S. 99-106 
    ISSN: 1619-1560
    Keywords: aortic blood velocity ; age ; Doppler ultrasound ; coronary artery disease ; stroke volume ; cardiac output
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The effect of age on aortic blood velocity has been studied in 100 patients with angiographically-documented coronary artery disease, 50 of whom were receiving β-adrenergic blocking agents. Using continuous-wave Doppler ultrasound, the aortic blood velocity signals, both at rest and at maximal-tolerated supine exercise, were obtained. From the Doppler signals the peak velocity (Vp), stroke distance (Sd; the velocity-time integral) and minute distance (Md=Sd×heart rate) were calculated. The measurements were repeated 6 weeks after coronary artery bypass grafting (CABG), performed in 30 patients. No relationship with age (p〈0.01) was found for any of the indices, either at rest or during exercise, except for the resting Md in patients not on β-blockers (p〈0.02). No difference in the slope of the relationship with age was found between patients on or not on β-blockers, except for the resting Md (p〈0.02). Following CABG, a significant age relationship with Vp, Sd and Md was restored, during both resting and exercise, suggesting improvement of systolic left ventricular function following myocardial revascularization. In conclusion, the normal age relationships of the derivatives of aortic blood velocity Doppler ultrasound signals were not seen in patients with coronary artery disease, irrespective of whether they were on or off β-blockers. The relationship changed following myocardial revascularization, suggesting their dependence on systolic left ventricular function.
    Type of Medium: Electronic Resource
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