Library

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    ISSN: 1432-1173
    Keywords: Schlüsselwörter Magnetresonanztomographie ; MRT ; Haut ; In-vivo-Histometrie ; Tumore ; Keywords MRT ; Skin ; Thickness ; Dermatology ; Tumors
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Purpose: To characterize human skin qualitatively and quantitatively using high-resolution magnetic resonance tomography (MRT) and to compare skin thickness measurements from MRT and histological specimens. Material and Methods: The skin of 84 persons was examined by use of a 2.5 cm coil in a whole-body tomography (gradient field strength 1.5 T) at a linear resolution of 100 μm. To evaluate the ability to identify various skin structures, following an initial visual description, the signal-noise and contrast-noise ratios were analyzed and the MRT-image compared to the corresponding histological specimen. Results: Using the high-resolution coil, epidermis, dermis and subcutis were discernible. Problem areas included the cheek, distal leg and foot. Reproducible measuring of skin thickness with MRT is possible, but it does not correlate well with conventional histologic measurements.
    Notes: Zusammenfassung Ziel: Anhand von In-vivo-Untersuchungen war die Schnittbildanatomie der Haut hinsichtlich ihrer bislang unbekannten Erscheinung im hochauflösenden Magnetresonanztomogramm (MRT) zunächst qualitativ und quantitativ zu charakterisieren. Anschließend sollte der Wert der MRT hinsichtlich der Hautdickenmessung anhand eines Vergleiches mit histologischen Schnitten analysiert werden. Methodik: In einer prospektiven Studie wurde die Haut von 84 Personen mit Hilfe eines 2,5 cm großen Spulenkopfes in einem Ganzkörpertomographen (Gradientenfeldstärke: 1,5 T) bei einer linearen Auflösung von 100 μm untersucht. Zur Bewertung der Abgrenzbarkeit verschiedener Hautstrukturen wurden nach visueller Charakterisierung deren Signal-Rausch- und deren Kontrast-Rausch-Verhältnisse objektiviert und ein Vergleich mit histologischen Präparaten vorgenommen. Ergebnisse: Mit der Hochauflösungsspule lassen sich Epidermis, Dermis und Subkutis differenzieren (p〈0,05). Problematisch ist dies nur an Wange, distalem Unterschenkel und Fuß. Hautdickenmessungen mit der MRT sind zuverlässig möglich. Die Ergebnisse korrelieren aber nicht mit jenen der Histologie.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of cardiac surgery 12 (1997), S. 0 
    ISSN: 1540-8191
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract An analysis of three-dimensional movement of the mitral valve annulus (MVA) may address the question of geometrical change after mitral valve repair to preserve mitral annular function. Conventionally, annular contraction has been studied for this purpose. We investigated this geometrical change occurring in the anterior half of the MVA and discuss its clinical significance. Three-dimensional images of the MVA during systole were reconstructed from magnetic resonance images of eight normal subjects. The posterior half of the MVA exhibited translational motion. We assume that this portion, exhibiting translational motion as well as contraction, purely follows the motion of the left ventricular contraction. Compensating for the discrepancy between the motion of the aortic root and that of the posterior half of the MVA, the anterior half exhibited a flexible change in shape during systole, thus maintaining a sufficient left ventricular outflow tract (LVOT). The increase in the extent of displacement of the anterior MVA from the posterior half of the MVA during systole, which was 3.6 ± 1.0 mm (mean ± SD), indicates the annular flexibility. The preservation of annular flexibility may prevent LVOT obstruction. Further geometrical analysis of patients after mitral repair will clarify annular function as presented in this article.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 3
    ISSN: 1619-7089
    Keywords: Technetium-99m sestamibi ; Tracer washout ; Tracer redistribution ; Exercise studies
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The aim of this study was to assess whether a clinically relevant change in myocardial sestamibi activity could be documented within the first 120 min following injection (p.i.). In 17 patients planar anterior imaging of the heart was performed 5 min and 120 min p.i. During this time interval, mean decay-corrected myocardial activity declined to 77.9%±9.7% after stress and to 85.7%±7.9% after injection at rest (P〈0.05). In 19 patients with angiographically documented coronary artery disease, single-photon emission tomography was performed 5 min and 120 min after injection at maximum stress. For analysis, sestamibi activity was scored semiquantitatively in six left ventricular segments. Furthermore, sestamibi uptake was assessed quantitatively using a circumferential profile method. In 35 of 114 segments the score improved within 120 min p.i. (early fillin); in these segments relative sestamibi activity rose from 69.9%±22.5% to 74.5%±20.8% (P〈0.01). In five patients this early fill-in was the only sign of exercise-induced hypoperfusion. In 7 of 114 segments the score deteriorated 120 min p.i. (early tracer washout); in these segments relative sestamibi activity declined from 85.6%±9.9% to 80.1%±10.7% (P〈0.02). In three of four patients with early tracer washout the corresponding coronary artery was significantly narrowed. In conclusion, a global myocardial sestamibi washout was registered within the first 120 min after injection. A fill-in of initial defects as well as an early tracer loss could be detected in a relevant number of patients with chronic coronary artery disease during the first 2 h p.i. In these patients the extent of detected reversible perfusion abnormality depends on the chosen time interval between injection and imaging. The results of this study suggest that exercise imaging should be started immediately after injection.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 4
    ISSN: 1433-0423
    Keywords: Key words Magnetic resonance imaging • Lacrimal drainage system • Stenosis ; Schlüsselwörter Magnetresonanztomographie • Tränenwege • Stenose
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Hintergrund: Dakryozystographie und Dakryoszintigraphie sind etablierte bildgebende Verfahren in der Diagnostik von Tränenwegstenosen. Beide erlauben nur indirekte Aussagen zur Morphologie des tränenableitenden Systems. Es wird untersucht, inwiefern mit Hilfe der Magnetresonanztomographie (MRT) neben der direkten detaillierten Darstellung der Tränenwege auch funktionelle Aussagen getroffen werden können, um die Rolle der Methode im Spektrum der bildgebenden Verfahren bei Tränenwegerkrankungen zu definieren. Patienten und Methoden: Es wurden 27 Tränenwegsysteme von 23 Patienten mit Epiphora in einem Ganzkörpermagnetresonanztomographen mit einer Oberflächenspule vor und nach konjunktivaler und intravenöser Gabe von Gd-DTPA untersucht. Ergebnisse: Passagestörungen wurden in 23 von 27 Tränenwegsystemen gefunden, konnten den Canaliculi lacrimales (n = 3), dem Saccus lacrimalis (n = 8) und Ductus nasolacrimalis (n = 12) zugeordnet, in Stenosen und Verschlüsse unterteilt werden und teilweise ätiologisch charakterisiert werden. Schlußfolgerungen: Die hochauflösende MRT mit konjunktivaler Kontrastmittelapplikation erlaubt neben der direkten und detaillierten Darstellung der ableitenden Tränenwege und periduktaler Strukturen zugleich eine funktionelle Beurteilung des Tränenwegsystems. Limitierungen einer verbreiteten Anwendung resultieren u. a. aus Anforderungen an gerätetechnische und patientengebundene Voraussetzungen sowie aus Kostengründen.
    Notes: Summary Both dacryocystography and dacryoscintigraphy are well established in the evaluation of stenoses of the lacrimal drainage system. They provide limited information about the ductal anatomy itself and about periductal structures. MR imaging was evaluated for its capability to directly visualize the lacrimal drainage system in detail and simultaneously provide functional characterization of dacryostenosis. Subjects and methods: Twenty-seven lacrimal drainage systems of 23 patients suffering from epiphora were examined in an MR unit before and after conjunctival and intravenous application of Gd-DTPA using a surface coil. Results: Dacryostenosis was found in 23 of 27 lacrimal systems. Stenoses were localized to the canalicular (n = 3), saccular (n = 8), and ductal (n = 12) level, and were classified as stenosis or occlusion. Conclusion: MR imaging with conjunctival contrast application allows within one examination both detailed morphological and functional assessment of the lacrimal drainage system with depiction of surrounding structures. Limitations arise mainly from demands on technical and patient-related preconditions.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 5
    ISSN: 1433-0423
    Keywords: Key words Dacryocystorhinostomy • Polyurethane stent • Stenosis of the nasolacrimal duct ; Schlüsselwörter Dakryozystorhinostomie • Polyurethan-Stent • Tränenwegsstenose
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Hintergrund: Die Dakryozystorhinostomie stellt noch immer das Standardverfahren bei absoluter Tränenwegsstenose dar. In letzter Zeit wurden Methoden entwickelt, die es ermöglichen, unter Beibehaltung der natürlichen Abflußwege eine Durchgängigkeit zu erzielen. Die auf der Seldingertechnik beruhende Methode der retrograden Implantation eines durchgängigen Polyurethan-Röhrchens in den Ductus nasolacrimalis ist eine vielversprechende Alternative. Patienten und Methoden: Es wurden 30 Patienten mit einer radiologisch gesicherten Tränenwegsstenose therapiert, darunter 15 Patienten mit absoluter und 2 mit relativer postsakkaler Tränenwegsstenose. Das Alter betrug 22–87 Jahre (Mittelwert 58,9 ± 16 Jahre). Der Polyurethan-Stent wurde unter Durchleuchtungskontrolle implantiert. Seine Durchgängigkeit wurde direkt postoperativ, nach 4 Wochen und nach 8 Monaten mittels Dakryozystographie kontrolliert. Ergebnisse: Insgesamt wurden 25 kurze (35 mm) und 5 lange (45 mm) Stents implantiert. Letztere reichten bis in den Canaliculus superior. Bei 24 von 30 Patienten konnte auch nach 4 Wochen und bei 9 von 10 Patienten nach 8 Monaten Durchgängigkeit des Stents klinisch nachgewiesen werden. Bei einer Patientin mußte der Stent unter Durchleuchtungskontrolle wieder rekanalisiert werden. Bei einem weiteren Patienten kam es zu einer Verlagerung eines kurzen Stents in den oberen Kanalikulus, so daß er nach 2 Monaten gezogen werden mußte. Postoperative Dakryozystitiden traten bei keinem der Patienten auf. Schlußfolgerung: Erfolgs- und Komplikationsraten lassen den Polyurethan-Stent als eine echte Alternative zur Toti-Operation erscheinen, wenngleich die Nachkontrollzeiten noch zu kurz für eine abschließende Beurteilung sind. Die Vorteile liegen im geringeren Zeitaufwand, der fehlenden Hautinzision und der problemloseren Anästhesie, die Nachteile in der bisherigen Notwendigkeit einer Durchleuchtungseinheit.
    Notes: Summary Dacryocystorhinostomy is still the standard procedure complete stenosis of the nasolacrimal duct. New methods try to preserve the natural lacrimal pathway. Song implanted in 1995 a nasolacrimal polyurethane stent through the nasolacrimal duct. The results and complications of this new method are described in this prospective study. Methods: Thirty consecutive patients with complete obstruction of the nasolacrimal duct or lacrimal sac were included in the study. The stenosis was localized by dacryocystography. The ages ranged from 22 to 87 years (mean, 58.9 ± 16 years). Dacryocystography was performed immediately, 4 weeks and 8 months after the procedure to verify the position and patency of the stent. Results: Twenty-five short (35 mm) and 5 long (45 mm) stents were implanted. Twenty-four of 30 patients after 4 weeks and 9 of 10 patients after 8 months had reduced or no complaints. In 1 patient the stent was obstructed. Forceful irrigation with saline solution permitted recanalization. In 1 patient the stent had moved into the upper canaliculus. Because of irritation of the canaliculus it had to be pulled out after 2 months. Conclusion: The follow-up is still too short to recommend stent implantation as a real alternative to dacryocystorhinostomy. The main advantages are that the procedure is faster, no incision is necessary, and the local anesthesia is easier. The disadvantage is the need for X-ray examination.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 6
    ISSN: 1432-1998
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 7
    ISSN: 1432-2277
    Keywords: Key words Doppler sonography ; Acute rejection ; Chronic rejection ; Tacrolimus ; Kidney transplantation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The aim of the present study was to differentiate acute rejection, chronic rejection, and tacrolimus nephrotoxicity with color and power Doppler imaging of renal transplants. One hundred examinations were obtained from 45 patients. Pulsatility and resistive indices were calculated from color Doppler images. The grade of renal vascularization was quantified using computer-assisted pixel analysis in a rectangular region-of-interest. The percentage of vessel-covered renal parenchyma (POV) was calculated using a histogram that discriminated renal vessels from renal parenchyma via power Doppler images. Furthermore, the distance from the most peripherally located vessels to the renal capsule (PVD) was measured. A reduced POV K 55 % proved to be the best discriminator when chronic rejection was suspected (sensitivity 79 %, specificity 87 %). Tacrolimus nephrotoxicity showed not only a moderate elevation of the Doppler signal but also an increased PVD L 3.9 mm and a normal POV. We conclude that the evaluation of renal vessels by power Doppler images improves diagnostic accuracy for patients with renal allografts.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 8
    ISSN: 1432-2161
    Keywords: Key words Femoral torsion ; Torsional difference ; Ultrasound ; Femoral fractures ; Anterior condylar line
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  Objective. A torsional difference of more than 15° is found in up to 30% of patients following closed intramedullary nailing of femoral fractures. The diagnosis is usually established postoperatively by computed tomography. A torsional deformity of more than 15° should be corrected by early derotation. In order to enable an intraoperative control and possible correction to avoid a second operation for the patient, a new ultrasound-based method suitable for the intraoperative setting has been developed, using the anterior condylar line as a distal reference line. Design and patients. In a prospective study the torsional difference after closed intramedullary nailing of femoral fractures was measured postoperatively by ultrasound in 32 patients and compared with standard CT readings. Results. Torsional differences measured by ultrasound and CT showed a high correlation (r=0.8) and a median difference of less than ±3°. Conclusions. By the introduction of the anterior condylar line as a distal reference line femoral torsion can accurately be assessed by ultrasound in a position required for intraoperative control and possible correction.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 9
    ISSN: 1615-3146
    Keywords: Kerspintomographie ; Kollateralbandruptur ; Knorpelläsion ; Hochauflösende Oberflächenspule ; Magnetic resonance imaging ; Collateral ligament rupture ; Cartilage lesion ; High-resolution coil
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Abstract Aim of this study was the evaluation of a prototype of a new high-resolution MRI coil for the detection of finger trauma. The practicability of this new coil for the assessment of traumatic lesions of the finger joints and the diagnostic value of this new method in clinical practice was assessed. Twenty patients between 13 and 50 years of age (mean 28 years) were examined with a 1.5-T whole-body-imager Magnetom SP 63 scanner (Siemens, Erlangen, Germany). A prototype of a high-resolution MRI coil with a diameter of 2.5 cm was used. T1- and T2-weighted images with an in plane resolution of 0.I95 x 0.098 mm were acquired. Bone structures, joint cartilage and capsule, ligaments, tendons and soft tissue alterations were assessed. All 19 patients with pathological changes at the finger joints had a joint effusion. With MR imaging, fractures were detected in almost all patients, compared with the X-ray examinations. Cartilage contusion showed high signal intensity. The collateral ligaments could best be assessed in the transversal, and ligament ruptures in the coronal plane. Hemorrhage in the tendon showed an increased signal intensity in T1- and T2-weighted, edema only in T2-weighted images. Especially traumatic lesions of cartilage and of ligaments can be sufficiently assessed by the high-resolution MRI due to its high anatomic resolution compared to common methods like X-ray. High-resolution MRI is practicable in clinical routine.
    Notes: Zusammenfassung Ziel der vorliegenden prospektiven Untersuchung war es, die Wertigkeit der hochauflösenden Kernspintomographie mittels einer speziellen Oberflächenspule in der Beurteilung von traumatischen Veränderungen der Fingergelenke zu evaluieren. Ferner sollte die Praktikabilität der Methode in der klinischen Routine überprüft werden. Es wurden 20 Patienten im Alter zwischen 13 und 50 Jahren (im Mittel 28 Jahre) an einem 1,5-T-Ganzkörpertomographen (Magnetom SP 63, Firma Siemens, Erlangen) untersucht. Als Spule wurde ein Prototyp einer hochauflösenden Oberflächenspule mit einem Durchmesser von 2,5 cm benutzt. T1- und T2-gewichtete Sequenzen mit einer maximalen Auflbsung in der Bildebene von 0,195 x 0,098 mm wurden zur Beurteilung von Knochen, Gelenkknorpel und -kapsel, der Sehnen und des Weichteilgewebes akquiriert. Kernspintomographisch fand sich bei 19 Patienten ein pathologischer Befund. Bei all diesen Patienten konnte ein Gelenkerguß nachgewiesen werden. Knöcherne Absprengungen, die anhand konventioneller Röntgenaufnahmen diagnostiziert wurden, zeigten sich kernspintomographisch als dislozierte signalreiche Strukturen. Gelenkknorpelkontusionen stellten sich hyperintens dar. Zur Beurteilung der Kollateralbānder eignete sich vor allem die koronare Schichtebene, da in dieser die Kollateralbdnder per continuitatem darstellbar sind. Sehneneinblutungen wiesen eine Signalerhöhung in T1- und T2-Wichtung auf. Ödeme der Weichteile und Bandstrukturen imponierten in T2-gewichteten Aufnahmen als signalreiche Strukturveränderungen. Aufgrund der hohen anatomischen Detailerkennbarkeit eignet sich die hochauflbsende Kernspintomographie als ergänzendes diagnostisches Verfahren zur nichtinvasiven Diagnostik von traumatischen Knorpel- und Bandläsionen. Unter Berücksichtigung des Zeitaufwandes handelt es sich dabei um eine im klinischen Alltag praktikable Methode.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Magnetic resonance materials in physics, biology and medicine 4 (1996), S. 19-25 
    ISSN: 1352-8661
    Keywords: magnetic resonance imaging ; cardiac activation sequence ; Fourier phase analysis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Physics
    Notes: Abstract To establish cardiac MRI as a tool for noninvasive evaluation of activation patterns, 10 healthy volunteers were examined by cine segmented turboFLASH imaging sequences. Sequence modifications for low signal blood-pool appearance were applied, i.e., bilateral spatial saturation for segmented turboFLASH imaging. Pixelwise calculation of first-harmonic Fourier phase values (displayed as color-encoded maps) reveal either anterior septal or left ventricular free-wall sites as areas of earliest phase spreading towards posterior paraseptal sites in segmented turboFLASH scans. Phase scatter is lower in unsaturated than spatially presaturated segmented turboFLASH studies. Phase standard deviation in areas of endocardial displacement is higher in basal than apical slice positions in these scans. Early results indicate that first-harmonic Fourier phase analysis of cardiac-segmented turboFLASH MRI cine studies may provide a tool for noninvasive studies of cardiac activation sequence.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...