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  • 1
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Inorganic chemistry 34 (1995), S. 2870-2874 
    ISSN: 1520-510X
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Pure and applied geophysics 152 (1998), S. 551-577 
    ISSN: 1420-9136
    Keywords: Key words: Failure criterion, circumferential strain, brittle rock, peak load, critical tensile strain, tensile strain criterion.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Notes: Abstract —Uniaxial compression, triaxial compression and Brazialian tests were conducted on several kinds of rock, with particular attention directed to the principal tensile strain. In this paper we aim to clarify the effects of the experimental environment—such as confining pressure, loading rate, water content and anisotropy—on the critical tensile strain, i.e., the measured principal tensile strain at peak load.¶It was determined that the chain-type extensometer is a most suitable method for measuring the critical tensile strain in uniaxial compression tests. It is also shown that the paper-based strain gage, whose effective length is less than or equal to a tenth of the specimen’s diameter and glued on with a rubber-type adhesive, can be effectively used in the Brazilian tests.¶The effect of confining pressure P C on the critical tensile strain ɛ TC in the brittle failure region was between −0.02 × 10−10 Pa−1 and 0.77 × 10−10 Pa−1. This pressure sensitivity is small compared to the critical tensile strain values of around −0.5 × 10−2. The strain rate sensitivities ∂ɛ TC /∂{log(d|ɛ|/dt)} were observed in the same way as the strength constants in other failure criteria. They were found to be from −0.10 × 10−3 to −0.52 × 10−3 per order of magnitude in strain rate in the triaxial tests. The average magnitude of the critical tensile strain ɛ TC increased due to the presence of water by 4% to 20% for some rocks, and decreased by 22% for sandstone. It can at least be said that the critical tensile strain is less sensitive to water content than the uniaxial compressive strength under the experimental conditions reported here. An obvious anisotropy was observed in the P-wave velocity and in the uniaxial compressive strength of Pombetsu sandstone. It was not observed, however, in the critical tensile strain, although the data do show some variation.¶A "tensile strain criterion" was proposed, based on the above experimental results. This criterion signifies that stress begins to drop when the principal tensile strain reaches the critical tensile strain. The criterion is limited to use within the brittle failure region. The critical tensile strain contains an inelastic strain component as well as an elastic one. It is affected by the strain rate, however, it is relatively insensitive to the confining pressure, the presence of water and anisotropy.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Pure and applied geophysics 149 (1997), S. 115-127 
    ISSN: 1420-9136
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Notes: Abstract It is widely acknowledged that the 1964 Niigata, Japan, earthquake is associated with the preseismic anomalous crustal movement detected by repetition of precise levelings, while some doubts have been raised on the validity of reported precursory movement. Validity of the crustal movement is tested by an analysis of tidal data. When we are able to deduce crustal movement referring to the determined mean sea level, we can discuss the absolute crustal movement. Tidal data along the Japan Sea coast of northeast Japan are analyzed by the method developed inTsumura (1963, 1970) for the period from 1955 to 1986. The final results at tidal station, Nezugaseki, indicate clearly the steady-state movement during 1955–1958, 4 cm of abnormal upheaval from 1959–1964, 20 cm of coseismic abrupt subsidence, and 4 cm of postseismic rapid subsidence, and finally very gradual subsidence. Thus the present results support the idea of the typical pattern of the seismic crustal movement, including the precursory movement.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1432-0428
    Keywords: Quick-freezing ; deep-etching ; glomerulus ; insulin treatment ; streptozotocin-diabetic rats
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The three-dimensional ultrastructure of glomerular basement membrane (GBM) and mesangial matrix (MM) at an early stage of streptozotocin (STZ)-induced diabetes mellitus in rats was examined by the quick-freezing and deep-etching method. In diabetic rats, the GBM inner layer was diffusely enlarged and the meshwork structure not only in the GBM middle layer but also in the MM became markedly irregular due to the rupture of fine fibrils. This irregularity and enlargement of the mesh pores in diabetic rats developed during the experimental period and was significantly different from results in control rats. Insulin treatment from 1 week after STZ injection had significant effects in preventing the ultrastructural changes in the GBM and MM. It is suggested that early insulin treatment has significant effects in preventing size barrier disturbance of GBM and MM in STZ-induced diabetes.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1432-0428
    Keywords: Keywords Quick-freezing ; deep-etching ; glomerulus ; insulin treatment ; streptozotocin-diabetic rats.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The three-dimensional ultrastructure of glomerular basement membrane (GBM) and mesangial matrix (MM) at an early stage of streptozotocin(STZ)-induced diabetes mellitus in rats was examined by the quick-freezing and deep-etching method. In diabetic rats, the GBM inner layer was diffusely enlarged and the meshwork structure not only in the GBM middle layer but also in the MM became markedly irregular due to the rupture of fine fibrils. This irregularity and enlargement of the mesh pores in diabetic rats developed during the experimental period and was significantly different from results in control rats. Insulin treatment from 1 week after STZ injection had significant effects in preventing the ultrastructural changes in the GBM and MM. It is suggested that early insulin treatment has significant effects in preventing size barrier disturbance of GBM and MM in STZ-induced diabetes. [Diabetologia (1996) 39: 632–640]
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 0942-0940
    Keywords: Intracerebral haemorrhage ; spontaneous cerebral haemorrhage ; amyloid angiopathy ; surgery
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Nineteen patients with massive lobar haemorrhage without angiographic lesions received direct or stereotactic surgery, and biopsy specimens were examined histologically. Ten patients (53%) were found to have vessels positive for Congo-red staining, and demonstrating amyloid angiopathy. In the patients with amyloid angiopathy, CT scan and surgical findings were investigated. Subarachnoid haemorrhage (9/10), irregularly shaped haematoma (9/10) and fluid-blood density level in the haematoma cavity (7/10) were frequently found on CT scan. The characteristic surgical findings in patients treated by direct surgery were subarachnoid haemorrhage adjacent to intracerebral haematoma (8/8) and the existence of a tangle of vessels in the haematoma cavity (4/8). Evacuation of haematomas was relatively easy, and difficulty of haemostasis was not encountered during surgery.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Melbourne, Australia : Blackwell Science Pty
    Clinical and experimental pharmacology and physiology 26 (1999), S. 0 
    ISSN: 1440-1681
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: 1. Effects of anti-Parkinsonian drugs on neurobehavioural changes induced by bilateral lesions of dopaminergic neurons were investigated in rats.2. Dopaminergic neurons in rats were lesioned bilaterally by injection of 6-hydroxydopamine (6-OHDA; 8 μg) into the medial forebrain bundle at the level of the posterolateral hypothalamus. As a result, a decrease in locomotor activity and marked catalepsy and prolongation of grasping time were observed.3. Levodopa, talipexole, bromocriptine and theophylline dose-dependently antagonized the decrease in locomotor activity induced by bilateral 6-OHDA lesions. These drugs also showed antagonistic effects on the appearance of catalepsy and prolongation of grasping time induced by bilateral 6-OHDA lesions. In contrast, trihexyphenidyl showed no antagonizing effect on the neurobehavioural changes induced by 6-OHDA lesions at any concentration tested.4. Combined treatment with levodopa and talipexole antagonized the neurobehavioural changes induced by bilateral 6-OHDA lesions, whereas no marked changes were observed when either drug was administered separately. The same findings were noted with the simultaneous use of either levodopa (2 mg/kg) and theophylline (2 mg/kg) or talipexole (0.005 mg/kg) and theophylline (2 mg/kg).5. These results indicate that this model may be useful for estimating the effects of drugs in the treatment of Parkinson's disease.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 77 (1995), S. 1189-1193 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Mössbauer spectra of 57Fe-doped polycrystalline CuO/Al2O3 multilayers (CAOs) show magnetic ordering at liquid helium temperature. The Néel temperature of a CAO with thin CuO layers is lower than that of bulk CuO judged from the temperature dependence of the Mössbauer spectra. A paramagnetic component was observed in all magnetic susceptibility measurements of the multilayers. The component also exists in both polycrystalline and epitaxial CuO/MgO multilayers. We have found that the component was localized at interfaces and derived from the spin fluctuation effect. © 1995 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Oxford : Blackwell Science Ltd
    Anaesthesia 54 (1999), S. 0 
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: We investigated the accelographic train-of-four response evaluated at the great toe at varying stimulating currents. Fifteen adult patients undergoing elective general anaesthesia were studied. The mean current at which a supramaximal T1 value could be elicited was 〉 49 (9) mA [mean (SD)]. Ratios of accelographic T1 values at 50, 40, 30, 20 and 10 mA to accelographic T1 value at 60 mA were 0.90 (0.18), 0.58 (0.37), 0.38 (0.37), 0.19 (0.26) and 0.00 (0.00), respectively [mean (SD), p 〈 0.05 for 50 mA vs. 30, 20 and 10 mA, p 〈 0.05 for 40 mA vs. 20 and 10 mA, and p 〈 0.05 for 30 vs. 10 mA]. Threshold currents for train-of-four (the lowest currents at which any train-of-four response could be elicited) before and after induction of anaesthesia were 30 (10) and 31 (10) mA, respectively. The train-of-four ratio (T4/T1) measured at varying currents did not differ significantly. However, in the patients in whom threshold currents for train-of-four were 40, 30 and 20 mA, the train-of-four ratio recorded at the threshold current was significantly less than at 50 mA. We conclude that at the great toe, the mean current at which a supramaximal response to train-of-four can be yielded is as high as 〉 49 mA. The mean threshold currents for TOF before and after induction of anaesthesia were 30 and 31 mA, respectively. Train-of-four ratio measured at the threshold current is less than that at 50 mA.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The efficacy of granisetron, droperidol and metoclopramide for the prevention of postoperative nausea and vomiting in female patients undergoing middle ear surgery was compared. In a randomised, double-blind study, 180 patients received granisetron 40 μg.kg−1, droperidol 20 μg.kg−1 or metoclopramide 0.2 mg.kg−1 given intravenously immediately before induction of anaesthesia (n = 60 for each). A standardised general anaesthetic technique was employed throughout. A complete response, defined as no postoperative nausea and vomiting and no need for another rescue anti-emetic, during the first 3 h after anaesthesia was achieved in 83%, 58% and 55% of patients who had received granisetron, droperidol and metoclopramide, respectively. The corresponding incidence during the next 21 h after anaesthesia was 85%, 54% and 47% (p 〈 0.05). No clinically important adverse effects were observed in any of the groups. We conclude that prophylactic therapy with granisetron is superior to droperidol or metoclopramide in the prevention of postoperative nausea and vomiting after middle ear surgery.
    Type of Medium: Electronic Resource
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