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  • 1
    Electronic Resource
    Electronic Resource
    Mobilities of Li+ in Ne and in N2 and Na+ in SF6: Effect of inelastic energy loss (1996)
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 105 (1996), S. 3031-3034 
    Details
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: Ion mobility measurements were made for Li+ in Ne and in N2 and Na+ in SF6 using a variable-temperature drift tube. The measurements were made by two different methods: variable-E/N method at constant T and variable-T method at constant E/N, where E, N, and T are the electric field strength, the gas number density, and the gas temperature, respectively. Two datasets were compared at the same effective temperature Teff, as calculated from the Wannier equation. For Li+ in Ne, the two datasets are put on a single curve in the range 150 K〈Teff〈10 000 K, indicating that the scaling rule holds well. However, for Li+ in N2 and Na+ in SF6 there exists a mobility difference between the two datasets, which is attributed to inelastic energy loss in the variable-E/N measurement. Using the modified Wannier equation developed by Viehland et al., we determined the inelastic energy loss factor for Na+ in SF6. © 1996 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.472168
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  • 2
    Electronic Resource
    Electronic Resource
    An isolated silicon single chain end-grafted onto a substrate surface (1999)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 75 (1999), S. 781-783 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: We report atomic force microscopy images of one-dimensional silicon chains (polysilanes) individually bonded to a substrate surface [quartz glass (SiO2), sapphire (Al2O3), and Si(111)]. The sample was prepared by a one-to-one chemical reaction between a reactive anchor of alkylbromide on the surface and a polysilanyl lithium. We observed dot images with variable densities which depended on the reactive anchor density. Each dot, with a diameter of about 20 nm and a height of about 5 nm, corresponded to an isolated single polysilane molecule with a collapsed structure typical of usual end-grafted polymers under poor solvent conditions. © 1999 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.124511
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  • 3
    Electronic Resource
    Electronic Resource
    Comment on "Crystal structure and optical properties of polymorphic octasilacubane'' [Appl. Phys. Lett. 64, 2509 (1994)] (1995)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 66 (1995), S. 1291-1291 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.113273
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  • 4
    Electronic Resource
    Electronic Resource
    Methanogenic granular sludge formation in an upflow anaerobic sludge blanket reactir treating synthetic methanolic waste (1995)
    Springer
    World journal of microbiology and biotechnology 11 (1995), S. 631-637 
    Details
    ISSN: 1573-0972
    Keywords: Anaerobic treatment ; granular sludge characteristics ; granulation ; methanolic waste ; UASB reactor
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Abstract A laboratory upflow anaerobic sludge blanket reactor, seeded with fine, suspended, bacterial floc with 1.76 g volatile suspended solids/l, was used to treat synthetic methanolic waste. After 180 days of continuous peration, granular sludge with discrete granules of 1 to 2 mm diam. was formed, with 52 g volatile suspended solids/l. Granules were brown, relatively soft and had a settling velocity of 1.61 cm/s. Extracellular polymeric matter extracted from the granular sludge had high carbohydrate content but low nucleic acid content. The ash of the granular sludge contained Na+, K+ and Mg2+ up to 15.0, 11.7 and 3.75 mg/g, respectively. Scanning and transmission electron microscopy revealed that the granular sludge was dominated by methanogens resembling Methanosarcina.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00361005
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  • 5
    Electronic Resource
    Electronic Resource
    An inflammatory fibroid polyp of the esophagus concomitant with a superficial flat carcinoma (1999)
    Springer
    International journal of clinical oncology 4 (1999), S. 302-306 
    Details
    ISSN: 1437-7772
    Keywords: Key words Inflammatory fibroid polyp ; Esophageal tumor ; Esophageal mucosal carcinoma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We report a rare case of an inflammatory fibroid polyp (IFP) of the esophagus associated with an extensive early mucosal carcinoma. At esophagoscopy, a polypoid lesion 2 cm in length, and a non-stained area detected by the Lugol iodine spray staining method were found in the mid-thoracic portion, and esophagectomy was performed. Endoscopic polypectomy is thought to be useful for the diagnosis of IFP, but it should be kept in mind that IFP may be concomitant with carcinoma. Indeed, in our patient, early esophageal carcinoma was discovered because of the symptoms of dysphagia induced by the IFP.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s101470050073
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  • 6
    Electronic Resource
    Electronic Resource
    Anti-apoptotic actions of cycloheximide: blockade of programmed cell death or induction of programmed cell life? (1997)
    Springer
    Apoptosis 2 (1997), S. 257-264 
    Details
    ISSN: 1573-675X
    Keywords: Antioxidant enzymes ; apoptosis ; Bcl-2 ; free radicals ; NF-kB ; protein synthesis ; transcription factors
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Cycloheximide (CHX), long recognized for its ability to inhibit protein synthesis, has been widely employed in studies of cell death to the extent that prevention of cell death by CHX has been used as prima facie evidence for a subtype of apoptosis called ‘programmed cell death’. However, very rarely have investigators determined the effects of CHX on protein synthesis in their particular cell death paradigms. Recent findings are revealing alternative mechanisms of action of CHX that involve, ironically, stimulation of cytoprotective signalling pathways. For example, in embryonic rat hippocampal cell cultures CHX protects neurons against oxidative insults by a mechanism involving induction of neuroprotective gene products including Bcl-2. CHX induces increases in immediate early gene mRNA levels, and can activate several different kinases and transcription factors that are also activated by various insults and in response to anti-apoptotic growth factors. Concentrations of CHX that cause only a modest and/or transient decrease in over-all protein synthesis may prevent cell death by inducing cytoprotective signalling pathways (‘programmed cell life’), whereas higher concentrations of CHX may prevent cell death by blocking the expression of ‘death genes’. Establishing which of these anti-apoptotic mechanisms of action of CHX is operative in each cell death paradigm is clearly essential for proper interpretation of experimental results.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1026433019210
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  • 7
    Electronic Resource
    Electronic Resource
    γ-Mangostin, a novel type of 5-hydroxytryptamine 2A receptor antagonist (1997)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 357 (1997), S. 25-31 
    Details
    ISSN: 1432-1912
    Keywords: Key wordsγ-Mangostin ; 5-Hydroxytryptamine ; 5-Hydroxytryptamine 2A receptor antagonist ; Rabbit aorta ; Rat coronary ; Rabbit platelet
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract γ-Mangostin, purified from the fruit hull of the medicinal plant Garcinia mangostana caused a parallel rightwards shift of the concentration/response curve for the contraction elicited by 5-hydroxytryptamine (5-HT) in the rabbit aorta (pA2 = 8.2) without affecting the contractile responses to KCl, phenylephrine (α1) or histamine (H1). The perfusion pressure response of rat coronary artery to 5-HT (5-HT2A) was reduced concentration dependently by γ-mangostin (IC50 = 0.32 μM). 5-HT amplified, ADP-induced aggregation of rabbit platelets (5-HT2A) was inhibited by γ-mangostin (IC50 = 0.29 μM), whereas that induced by thrombin was not affected, nor did γ-mangostin affect 5-HT-induced contraction of the guinea-pig ileum (5-HT3)in the presence of 5-HT1, 5-HT2 and 5-HT4 receptor antagonists. Furthermore, 5-HT-induced contraction of the rat fundus (5-HT2B) and 5-HT-induced relaxation of the rabbit aorta in the presence of ketanserin (5-HT1) and carbachol-induced contraction of the guinea-pig ileum (muscarinic M3) were not affected by γ-mangostin (5 μM). γ-Mangostin inhibited [3H]spiperone binding to cultured rat aortic myocytes (IC50 = 3.5 nM). The K d for [3H]spiperone binding was increased by γ-mangostin (3 nM) from 11.7 to 27.4 nM without affecting B max. These results suggest that γ-mangostin is a novel competitive antagonist, free from a nitrogen atom, for the 5-HT2A receptors in vascular smooth muscles and platelets.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/PL00005134
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  • 8
    Electronic Resource
    Electronic Resource
    Increased numbers of macrophages in noninflamed gastroduodenal mucosa of patients with Crohn's disease (1996)
    Springer
    Digestive diseases and sciences 41 (1996), S. 2260-2267 
    Details
    ISSN: 1573-2568
    Keywords: Crohn's disease ; macrophages ; stomach ; duodenum ; noninflamed mucosa
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We investigated immunostained macrophages in the noninflamed mucosa of Crohn's disease patients. Biopsied specimens from endoscopically normal gastroduodenal mucosa of Crohn's disease, ulcerative colitis, and healthy control patients were studied. Sections were examined immunohistochemically using a monoclonal antibody specific for tissue macrophages (CD68). Immunostained mucosal macrophages in the second part of the duodenum, duodenal bulb, gastric antrum, and gastric body of the Crohn's disease group were more numerous than in the ulcerative colitis and control groups. The characteristic findings of Crohn's disease were aggregations, focal subepithelial dense accumulations, and infiltration throughout the mucosa of macrophages not accompanied by a lymphoid infiltrate. The number of macrophages in the gastroduodenal mucosa bore no relationship with the duration of symptoms, clinical activity, or affected site in the intestine. This suggests that the increased number of macrophages in noninflamed mucosa is a histological change characteristic for Crohn's disease that indicates a persistent latent abnormality involving the entire gastrointestinal tract.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02071410
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  • 9
    Electronic Resource
    Electronic Resource
    Evaluation of 7 DNA markers (D1S80, HLA-DQα, LDLR, GYPA, HBGG, D7S8 and GC) in a Japanese population (1996)
    Springer
    International journal of legal medicine 109 (1996), S. 47-48 
    Details
    ISSN: 1437-1596
    Keywords: D1S80 ; D7S8 ; GC ; GYPA ; HBGG HLA-DQα ; LDLR
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Law
    Notes: Abstract A Japanese population was tested for the 7 DNA markers D 1 S 80, HLA-DQα, low-density lipoprotein receptor (LDLR), glycophorin A (GYPA), hemoglobin G gammaglobin (HBGG), D7S8 and group specific component (GC). Each of these 7 markers was found to be useful for paternity testing and individual identification in a Japanese population.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01369603
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