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  • 1
    Electronic Resource
    Electronic Resource
    GTR therapy of intrabony defects using 2 different bioresorbable membranes: 12-month results (1998)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of clinical periodontology 25 (1998), S. 0 
    Details
    ISSN: 1600-051X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract. This prospective split-mouth study was designed to compare the clinical and radiographic healing results in intrabony periodontal defects 12 months after GTR therapy with 2 different bioresorbable barriers. The study comprised 25 healthy patients with one pair of contralaterally located intrabony defects with a probing pocket depth of ≥6 mm and radiographic evidence of angular bone loss of ≥4 mm. The 2 defects of each patient were randomized for treatment either with polylactic acid (PLA) membranes or with polyglactin-910 (PG-910) membranes. The patients received systemic doxycycline (100 mg/d) for 11 days post-operatively. One blinded examiner recorded the following clinical parameters using a pressure calibrated probe at baseline and after 12 months: papillary bleeding index (PBI), gingival recession (REC), probing pocket depth (PPD), and probing attachment level (PAL). The vertical relative attachment gain (V-rAG) was calculated as a % of the PAL gain related to the maximum possible attachment gain (expressed by the intrraoperatively measured depth of the osseous defect). Geometrically standardized intraoral radiographs were quantitatively evaluated for bone changes (density, area) in the defect region using digital subtraction radiography (DSR). Clinical and radiographic data were statistically analyzed using the Wilcoxon-signed-rank test (α=0.05). Postoperative membrane exposures occurred in 9 PLA and 13 PG-910 treated sites. After 12 months of healing, both barrier types provided significant PPD reductions and PAL gain [median (25/75 percentile)]: ΔPPD (PLA: 3.0 (2.0/4.0) mm: PG-910: 3.0 (2.0/4.5) mm]; ΔPAL [PLA: 3.0 (2.5/4.0) mm: PG-910: 2.0 (1.0/4.0) mm]. V-rAG amounted to 60% in PLA sites and 54% in PG-910 sites. DSR revealed significant bone density gain after 12 months. 58.3% of she initial defect area in PLA sites and 54.0% of the initial defect area in PG-910 sites showed bone density gain. Neither clinical nor radiographic data revealed any significant difference between the 2 barrier types after 12 months. In conclusion, this 12-month study demonstrated that PLA and PG-910 membranes provided similar favorable regeneration results in deep intrabony periodontal defects.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-051X.1998.tb02479.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Periodontal regeneration of intrabony defects with resorbable and non-resorbable membranes: 30-month results (1997)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of clinical periodontology 24 (1997), S. 0 
    Details
    ISSN: 1600-051X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract The aim of this prospective split-mouth-study was to compare the healing results in intrabony defects 12 and 30 months after placement of resorbable (polyglactin-910) and non-resorbable (e-PTFE) GTR-membranes. 11 healthy patients with 30 defects participated. 10 patients with 10 pairs of contralateral lesions, which were treated with both membrane types, were included in the split-mouth-design. Furthermore, in an additional group-design all 30 (16 polyglactin-910 and 14 e-PTFE) treated sites were evaluated. Clinical examinations (PBI, REC, PPD, PAL) and radiographic examinations were carried out under standardized conditions immediately before as well as 12 and 30 months after surgery. Additionally, for the assessment of the effectiveness of the 2 membranes by comparing the regeneration results of different defects, the vertical relative attachment gain (V-rAG) was calculated as a% of the PAL gain related to the maximum possible attachment gain (expressed by the baseline depth of the osseous defect intraoperatively measured). Digital subtraction radiography (DSR) was carried out for the quantitative assessment of bone density changes due to GTR. In the split-mouth-design, both types of membranes provided significant V-rAGs (median) after 12 months (polyglactin: 81.7%: e-PTFE: 100.0%) and after 30 months (polyglactin: 69.1%: e-PTFE: 83.8%) compared to baseline. In 90.0% of the polyglactin and e-PTFE sites, a probing attachment gain of at least 2 mm was maintained over the 30-month period. However, in 2 polyglactin treated sites, and 5 e-PTFE treated sites, a new attachment loss was found between 12 and 30 months. DSR showed bone density gain 12 and 30 months postsurgically. No statistically significant differences could be observed between the 2 membrane materials with regard to clinical and radiographic findings. This was confirmed when considering the total number of defects (group-design). In conclusion, based on this 30-month-study resorbable polyglactin membranes may be regarded as a useful alternative to the well established e-PTFE membranes for the treatment of intrabony defects.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-051X.1997.tb01179.x
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  • 3
    Electronic Resource
    Electronic Resource
    Accuracy of quantitative digital subtraction radiography for determining changes in calcium mass in mandibular bone: an in vitro study (1998)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of periodontal research 33 (1998), S. 0 
    Details
    ISSN: 1600-0765
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The aim of this in vitro study was to determine the accuracy of digital subtraction radiography (DSR) to detect small changes in calcium mass in alveolar bone adjacent to tooth roots. In each of 4 dried porcine mandible segments, one interproximal and one buccal “defect” region was defined adjacent to a premolar root. A series of cortical and cancellous bone slices with a 50 μm-stepwise increasing thickness (0-5000 μm) were attached to the mandible segments covering the respective “defect” region. Standardized radiographs were quantitatively assessed for density changes using DSR. After dissolving each bone slice in hydrochloric acid, its calcium concentration was photometrically determined. For each bone slice, the mean calcium mass covering a single pixel of the subtraction image was calculated. The Wilcoxon signed-rank test and the Mann-Whitney U-test were used for statistical analysis (α = 0.05). A strong linear correlation (r2 = 0.86-1.00; p ≤ 0.001) was found between the thickness of the bone slices and their calcium mass. Cortical bone showed a 3.5 times higher mean calcium mass/pixel than cancellous bone. Furthermore, a strong linear correlation (r2 = 0.63-1.00; p ≤ 0.001) was found between the mean calcium mass per image pixel and the radiographic density changes. Neither the bone type nor the “defect” localization had a significant influence on radiographic density changes caused by changes in calcium mass. A change in mean calcium mass per image pixel of 0.1-0.15 mg was necessary to be detected by DSR. In conclusion, this study revealed a high accuracy of DSR to detect small changes in calcium mass in alveolar cortical and cancellous bone.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0765.1998.tb02304.x
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  • 4
    Electronic Resource
    Electronic Resource
    Postoperative exposure of bioresorbable GTR membranes: effect on healing results (1997)
    Springer
    Clinical oral investigations 1 (1997), S. 109-118 
    Details
    ISSN: 1436-3771
    Keywords: Key words Guided tissue regeneration ; Periodontal disease/surgery ; Intrabony defects ; Polylactic acid ; Polyglactin 910
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The goal of this investigation was to evaluate the effect of postoperative exposure of two different bioresorbable membranes on the guided tissue regeneration (GTR) healing results compared to nonexposed sites. In each of 25 patients one pair of contralateral intrabony lesions was treated either with polylactic acid (PLA) or polyglactin 910 (PG-910) membranes. Postoperative exposure occurred in 9 PLA and 13 PG-910 sites. Standardized clinical [papillary bleeding index (PBI), gingival recession (REC), probing pocket depth (PPD), probing attachment level (PAL)] and radiographic examinations (digital subtraction radiography) were performed immediately before (baseline) and 6 and 12 months postoperatively (p.o.). Subgingival bacterial samples from surgical sites were evaluated by culture at baseline, 6 weeks, and 6 and 12 months p.o. Six months after surgery the changes (Δ) of REC were significantly (P≤0.05) greater in exposed than in nonexposed sites, independently of the membrane material (median): exposed sites, ΔREC=–1 mm; nonexposed sites, ΔREC=0.0 mm. However, 12 months p.o. no significant differences were found due to a decrease in the initial recessions in exposed sites. Although a higher percentage of exposed than nonexposed sites harbored periodontal pathogens 6 weeks p.o. at the gingiva-faced membrane surface, membrane exposure did not have a significant negative effect on ΔPPD, ΔPAL, or radiographic bone density changes 6 and 12 months p.o. Both membranes showed significant gains in PAL and bone density in both exposed and nonexposed sites. In conclusion, this study demonstrates that with consistent infection control the postoperative exposure of PLA and PG-910 membranes has no significant negative effect on the regeneration outcome, although higher initial gingival recessions must be expected than in the nonexposed sites. However, in exposed sites plaque and infection control were clearly impeded by the rough, exposed membrane surfaces and by the initially negative gingival morphology.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s007840050021
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  • 5
    Electronic Resource
    Electronic Resource
    Clinical and quantitative marginal analysis of feldspathic ceramic inlays at 4 years (1998)
    Springer
    Clinical oral investigations 1 (1998), S. 163-168 
    Details
    ISSN: 1436-3771
    Keywords: Key words Ceramics ; Inlays ; Clinical trial ; Quantitative margin analysis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The aim of this clinical study was to evaluate feldspathic ceramic inlays both by clinical criteria and quantitative margin analysis in continuation of an earlier, identically conducted 2-year study. Fifty feldspathic ceramic inlays were adhesively luted in Class II preparations with all margins located in enamel. The inlays were evaluated clinically according to modified USPHS criteria after 3 and 4 years. Quantitative margin analysis was performed with a scanning electron microscope (SEM). Clinically, the inlays showed no recurrent caries and no changes in colour, but superficial marginal discolouration (6%) was apparent after 4 years. Margins were perceptible clinically in 64% of the cases after 4 years. Quantitative margin analysis showed significantly more marginal gaps at the composite/ceramic interface than at the enamel/composite interface. There was neither a significant decrease in perfect margins nor a significant increase in marginal gaps and marginal imperfections at both interfaces between the third and fourth year. Clinically, the inlays performed very well up to 4 years. Clinical evaluation using an explorer only detected substance loss in the cementation gap. The SEM evaluation showed significantly higher changes in marginal qualities during the first 2-year interval of clinical service compared to the second 2-year interval following an exponential mathematical regularity. Quantitative margin analysis should be included in clinical long-term trials to detect early marginal deficiencies at the luting interfaces.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s007840050028
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    Clinical performance of polyacid-modified resin restorations using ”softstart-polymerization” (1999)
    Springer
    Clinical oral investigations 3 (1999), S. 55-61 
    Details
    ISSN: 1436-3771
    Keywords: Key words Polyacid-modified resin ; Class V lesion ; Softstart-polymerization ; Clinical performance
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  This study investigated the influence of ”softstart-polymerization” on the clinical performance and marginal integrity of polyacid-modified resin restorations (PMR) in class V cavities. Eighty PMR restorations were placed in 20 patients [40 Dyract (DY); 40 Hytac (HY)] with (n pat =10) and without preparation (n pat =10). Restorations were light cured for 40 s either conventionally (CP) or with a lower light intensity for the first 10 s (SSP). Each patient received four restorations (DY-CP, DY-SSP, HY-CP, HY-SSP), which were examined clinically according to modified USPHS criteria, and by quantitative SEM-analysis after 7 days (baseline), 6 months and 1 year. Statistical analysis was performed using the Mann-Whitney-U test (P≤ 0.05) and error rates method. Clinically, no restoration showed recurrent caries or crevices. After 1 year, margins of 24–47% of the HY- and 36–53% of the DY-restorations were rated ”Bravo”. Marginal discoloration occurred in 20–37% in HY- and in 18–21% in DY-restorations. The error rates method revealed no significant differences between materials or between polymerization modes with and without preparation. Pairwise testing showed that without preparation, the marginal adaptation to dentin was significantly worse compared to enamel for HY with both polymerization modes, for DY with SSP. With preparation, no significant differences were found. Cavity preparation may have an influence on differences in marginal quality between enamel and dentin.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s007840050079
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  • 7
    Electronic Resource
    Electronic Resource
    Infrared spectroscopic characterization of the buried interface and surfaces of bonded silicon wafers (1998)
    Springer
    Fresenius' journal of analytical chemistry 361 (1998), S. 558-559 
    Details
    ISSN: 1432-1130
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract Basic investigations have been carried out on the characterization of different processing steps in bond preparation using etched 〈111〉 faces of silicon wafers for the incidence of the infrared beam to a multiple internal reflection geometry. The method is very sensitive to the surface coverage and interface. Surface activation by RCA cleaning yields an increase of water coverage and a decrease of SiH and CH groups. The detection limit for an oxide layer between silicon wafers has been found to be about 3 nm.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002160050946
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