Library

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • 1995-1999  (8)
  • 1
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Oligohydramnios-polyhydramnios sequence in twin pregnancies may be managed by aggressive amniocentesis and is described in nine consecutive cases. In four of the nine pregnancies both twins survived, one pair died in the neonatal period, and the other four pairs all suffered intrauterine death. The median number of amnioreductions performed was five (range 2–7). In this series the reaccumulation of urine in the bladder of the ‘stuck twin’ was a predictive prognostic marker of survival in both twins, with a sensitivity and specificity of 100%.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 102 (1995), S. 0 
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Objective To investigate whether low maternal haemoglobin and ferritin levels are associated with increased placental volume by mid-pregnancy.Design Prospective study of women attending hospital for shared antenatal care.Setting A teaching hospital in the south of England.Subjects Five hundred and sixty-eight women booking for delivery in the hospital.Main outcome measures Placental volume measured by ultrasound at 18 weeks gestation.Results At 14 weeks gestation 9% of women had haemoglobin levels ≤ 11 g/dl and 26% had ferritin levels 〈 13 μg/1. Placental volume at 18 weeks was inversely related to the maternal haemoglobin and ferritin levels. The influence of haemoglobin and ferritin concentrations was independent of maternal social class, parity, smoking, and weight. Larger placentae were found in taller women, those who had previously been pregnant, and in those who were smoking more than 15 cigarettes daily at the time of their last menstrual period.Conclusion These data suggest that placental development is influenced from early in pregnancy by the intrauterine environment provided by the mother. In conjunction with other studies they support the proposal that, as a result of these changes, programming of adult blood pressure may be initiated in early pregnancy.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 3
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The manufacture of anisotropic bonded permanent magnets involves the application of an aligning field during the moulding of the magnet, and in most cases, particularly those involving anisotropic NdFeB powder, the subsequent application of a considerably larger magnitude magnetizing field, which in turn is usually produced by a capacitor discharge magnetizer and a geometry specific fixture. A finite element based method for modeling both of the production stages is presented, and the method is validated by a case study, which includes extensive material characterization on a four-pole anisotropic NdFeB cylinder. © 1996 American Institute of Physics.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 4
    Electronic Resource
    Electronic Resource
    Oxford : Blackwell Science Ltd.
    Journal of neuroendocrinology 8 (1996), S. 0 
    ISSN: 1365-2826
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The hypothalamic mechanisms which underlie the development of the fetal neuroendocrine system are unclear. However, in adult animals neuroactive amino-acids, particularly those acting at the N-methyl-D-aspartate (NMDA) receptor, have been shown to be important transmitters involved in the neuroendocrine regulation of the anterior pituitary gland. In this study we have investigated the potential role of NMDA in the neuroendocrine regulation of fetal pituitary function, by examining the ontogeny of LH and ACTH responses to NMDA during fetal development in sheep. Catheterized fetal sheep were injected with 3 intravenous doses of NMDA (1, 2 and 4 mg/kg; estimated fetal body weight) and saline vehicle on consecutive days between days 110–115, 120–125 and 135–140 gestation (term=145 days). At each gestational age fetuses also received a pituitary challenge test consisting of CRF (0.4 μg/kg), AVP (80 ng/kg) and GnRH (125 ng/kg). NMDA caused a significant dose-related increase in ACTH at day 120–125 (P〈0.02) and day 135–140 gestation (P〈0.001). NMDA had no effect on ACTH secretion at day 110–115. The ACTH response to the highest does of NMDA (4 mg/kg) increased with advancing gestational age, in contrast to the ACTH response to CRF+AVP which was the same at all ages. NMDA caused a significant increase in LH secretion at all gestational ages with the greatest response observed at the latest gestational age studied (day 135–140). A similar increase in LH response to the GnRH challenge was observed late in gestation. Pretreatment of fetuses with the competitive NMDA antagonist CGP37849 (1 mg/kg) abolished the LH and ACTH responses to an intravenous injection of NMDA (4 mg/kg) given 5 min later. These data show that activation of NMDA receptors during fetal development elicits the secretion of ACTH and LH and demonstrate that NMDA receptors are functionally coupled to the neuroendocrine pathways regulating these two hormones during fetal life. The dramatic increase in ACTH repsonse to NMDA during the final days before birth occurs at a time of high adrenocortical activity and suggests an important functional role for these receptors at this time.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 5
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 81 (1997), S. 4266-4268 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: This paper describes a new form of actuator with a spherical permanent magnet rotor and a simple winding arrangement, which is capable of a high specific torque by utilizing a rare-earth permanent magnet. The magnetic-field distribution is established using an analytical technique formulated in spherical coordinates, and the results are validated by finite element analysis. The analytical field solution allows the prediction of the actuator torque and back emf in closed forms. In turn, these facilitate the characterization of the actuator and provide a firm basis for design optimization, system dynamic modeling, and closed-loop control law development. © 1997 American Institute of Physics.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 6
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 81 (1997), S. 4295-4297 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Position sensors are a key technology for controlled actuation systems, which are required to meet increasingly exacting dynamic performance specifications. Of the various sensing technologies, variable differential transformers are capable of satisfying stringent performance criteria, in terms of resolution, repeatability, and stability of output, while operating in the harshest of environments. They utilize the variation of mutual inductance which occurs between a primary and two secondary coils as a ferromagnetic core is moved by the object whose position is to be measured. The article is concerned with rotary variable differential transformers, which currently use high permeability magnetic alloys, such as nickel–iron, either solid or laminated. However, since they are being required to operate at increased excitation frequencies, up to 5 kHz, there is interest in the use of powder composite magnetic materials, which, although having a lower permeability, have a higher electrical resistivity, and hence reduced eddy current effects. The potential for such materials is investigated by steady-state ac finite element analysis, and shown to be promising. © 1997 American Institute of Physics.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 7
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 81 (1997), S. 4119-4121 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Iron losses can account for a significant portion of the total loss in electrical machines. Nevertheless, although analytical and numerical techniques have been developed for predicting the iron loss density distribution and the total iron loss of various types of machine under any operating load condition, to date these have neglected the effect of mechanical stress. However, during the manufacture of many electrical machines, a significant radial compressive stress can be imposed on the stator lamination stack, by shrink fitting/pressing an outer frame, for example. This paper describes a technique that has been developed for predicting the effect of compressive stress on the iron loss density in lamination materials, and demonstrates its use in calculating the iron loss of a permanent magnet brushless dc motor. © 1997 American Institute of Physics.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 8
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Molecular microbiology 22 (1996), S. 0 
    ISSN: 1365-2958
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: Coxiella burnetii undergoes a poorly defined developmental cycle within phagolysosomes of eukaryotic host cells. Two distinct developmental forms are part of this cycle: a small-cell variant (SCV) and large-cell variant (LCV). Ultrastructurally, the SCV is distinguished from the LCV by its smaller size and condensed chromatin. At a molecular level, little is known about morphogenesis in C. burnetii, and no proteins specific to the SCV have been identified. Preparative isoelectric focusing was conducted to purify basic proteins possibly involved in SCV chromatin structure. A predominant protein of low Mr was present in the most basic fraction, eluting with a pH of approx. 11. Degenerate deoxyoligonucleotides corresponding to the N-terminal sequence of this protein were used to recover a cosmid clone from a C. burnetii genomic library. Nucleotide sequencing of insert DNA revealed an open reading frame designated scvA (small-cell-variant protein A) with coding potential for a 30 amino acid protein (ScvA) with a predicted Mr of 3610. ScvA is 46% arginine plus 46% glutamine with a predicted pi of 12.6. SDS-PAGE and silver staining of lysates of SCV and LCV purified by caesium chloride-equilibrium density centrifugation revealed a number of proteins unique to each cell type. Immunoblot analysis with ScvA antiserum demonstrated the presence of ScvA only in the SCV. By immunoelectron microscopy, ScvA antiserum labelled only the SCV, with the label concentrated on the condensed nucleoid. In addition, ScvA bound double-stranded DNA in gel mobility-shift assays. A 66% reduction in the mean number of gold particles per Coxiella cell was observed at 12 h post-infection when compared with the starting inoculum. Collectively, these data suggest that synthesis of ScvA is developmentally regulated, and that the protein may serve a structural or functional role as an integral component of the SCV chromatin. Moreover, degradation of this protein may be a necessary prerequisite for morphogenesis from SCV to LCV.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...