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  • 1
    Electronic Resource
    Electronic Resource
    An Evaluation on H/V Ratio vs. Spectral Ratio for Site-response Estimation Using the 1994 Northridge Earthquake Sequences (1999)
    Springer
    Pure and applied geophysics 156 (1999), S. 631-649 
    Details
    ISSN: 1420-9136
    Keywords: Key Words: H/V ratio, spectral ratio, site response, microtremor, resonant frequency, amplification.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Notes: Abstract —The applicability of the single-station H/V method, based on the spectral ratio between the horizontal and the vertical components of strong ground motions, is examined for site-response estimation using the high quality data from the 1994 Northridge earthquake sequence. Instead of using Rayleigh-wave data from microtremors, the large amplitude-wave part of the S-wave data is used and based on the 1994 Northridge mainshock and aftershock recordings. We have found that upon averaging over a number of recordings for a given station, the station site responses, derived both from the single-station H/V ratio and from the standard spectral ratio (with respect to a reference rock-site station) are sufficiently close for practical purposes. We therefore conclude that the H/V ratio can reasonably predict the resonant frequency and the amplification level of a site response, especially for sites in the neighborhood of the epicenters. In the absence of a reference rock-site station, the H/V ratio provides a practical alternative to the standard site-response estimation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s000240050316
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  • 2
    Electronic Resource
    Electronic Resource
    Reflective twisted nematic liquid crystal displays. I. Retardation compensation (1997)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 81 (1997), S. 5924-5929 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Reflective twisted nematic displays where the output polarizer is eliminated are analyzed and demonstrated. The absence of the rear output polarizer has many advantages, including much higher brightness and higher resolution. In this article, we examine the solution space for the design of such reflective displays. Both the cases of a simple reflective display and the use of a retardation film within the display to compensate for color dispersion are explored. It is shown that excellent black and white displays can be obtained using film compensation. Experimentally, over 90% reflectance from a compensated reflective display has been obtained with low color dispersion. The optical response of this reflective display was also found to be quite fast and suitable for video rate applications. © 1997 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.364379
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  • 3
    Electronic Resource
    Electronic Resource
    On the initial growth of indium tin oxide on glass (1996)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 68 (1996), S. 2663-2665 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The initial growth mode of indium tin oxide on glass was studied. An interesting transition from a 3D island growth mode at low temperatures to 2D growth at higher temperature was observed. This transition from the Volmer-Weber mechanism to the Frank–van der Merwe mechanism occurs at about 150°C. It coincides with the transition from amorphous to polycrystalline growth of the thin films. © 1996 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.116274
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  • 4
    Electronic Resource
    Electronic Resource
    The ATP-dependent HslVU protease from Escherichia coli is a four-ring structure resembling the proteasome (1997)
    [s.l.] : Nature Publishing Group
    Nature structural biology 4 (1997), S. 133-139 
    Details
    ISSN: 1072-8368
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] HslVU is a new two-component protease in Escherichia coli composed of the proteasome-related peptidase HslV and the ATPase HslU. We have used electron microscopy and image analysis to examine the structural organization of HslV and HslU homo-oligomers and the active HslVU enzyme. Electron ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nsb0297-133
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  • 5
    Electronic Resource
    Electronic Resource
    Cytokeratin-19 associated with apoptosis and chemosensitivity in human cervical cancer cells (1997)
    Springer
    Apoptosis 2 (1997), S. 101-105 
    Details
    ISSN: 1573-675X
    Keywords: Apoptosis ; cytokeratin ; drug resistance
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Cytokeratins are one group of intermediate filament proteins responsible for the integrity of cell structure, and have been recently reported to play a role in conferring a drug resistance phenotype. MAb Cx-99 is a monoclonal antibody exhibiting the specificity toward its corresponding antigen which was recently identified as the cytokeratin-19 protein. In the present study, we found that the level of cytokeratin-19 in cervical cancer cells could be decreased by incubation of cancer cells with MAb Cx-99. The reduction of cytokeratin-19 level had a killing effect on cervical carcinoma SIHA and HeLa S3 cell lines. The DNA ladder pattern, convoluted nuclei and blebbing morphology were observed with these cells after exposure to MAb Cx-99 for 72 h, suggesting that the cytotoxic mechanism of reduced cytokeratin-19 was mediated by induction of apoptosis. Moreover, the MAb Cx-99 treatment could increase the cytotoxicities of cancer chemotherapeutic agents such as cisplatin and vinblastine to both cervical carcinoma cell lines. The LD80 values were at least 15-fold reduced when cancer cells were treated with cisplatin or vinblastine in the presence of MAb Cx-99. These results suggest that the functional role of cytokeratin-19 was associated with the apoptosis prevention and drug resistance of cervical cancer cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1026448027870
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  • 6
    Electronic Resource
    Electronic Resource
    Decrease in myocardial Na+-K+-ATPase activity and ouabain binding sites in hypercholesterolemic rabbits (1997)
    Springer
    Basic research in cardiology 92 (1997), S. 1-7 
    Details
    ISSN: 1435-1803
    Keywords: Hypercholesterolemia ; membrane lipid ; Na+−K+-ATPase ; ouabain receptor
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Objectives The purpose of this study was to explore the effect of high dietary cholesterol on the lipid composition, Na+−K+-ATPase activity and ouabain receptor property of the myocardial sarcolemma. Methods Male New Zealand white rabbits were fed with standard chow or standard chow supplemented with 0.5% (w/w) cholesterol and 10% (w/w) coconut oil to induce hypercholesterolemia. After 8 weeks, the rabbits were sacrificed; a myocardial sarcolemma fraction was then prepared from the left ventricular myocardium and analyzed for lipid composition. Assay of Na+−K+-ATPase activity and3H-ouabain binding studies were performed in the myocardial sarcolemma from the control and cholesterol-fed rabbits. Results The cholesterol content, but not the phospholipid content, of the sarcolemma was significantly greater in the cholesterol-fed group, thus, resulting in an increased cholesterol/phospholipid molar ratio in the cholesterol-fed group. In addition, a decrease in Na+−K+-ATPase activity was also found in this group. The decrease in Na+−K+-ATPase activity was selective, since the Mg++-ATPase and 5′-nucleotidase activities remained unchanged. In the3H-ouabain binding study, a decrease in the number of maximum binding sites, but not the binding affinity, for3H-ouabain was foundie the cholesterol-fed group. Conclusions High dietary cholesterol induces higher levels of cholesterol not only in the plasma, but also in the myocardial sarcolemma. These changes result in decreased myocardial Na+−K+-ATPase activity mediated by a reduction in the maximum number of binding sites for ouabain but not a change in binding affinity.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00803751
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  • 7
    Electronic Resource
    Electronic Resource
    Decrease in myocardial Na+-K+-ATPase activity and ouabain binding sites in hypercholesterolemic rabbits (1997)
    Springer
    Basic research in cardiology 92 (1997), S. 1-7 
    Details
    ISSN: 1435-1803
    Keywords: Key words Hypercholesterolemia – membrane lipid – Na+-K+-ATPase – ouabain receptor
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Objectives: The purpose of this study was to explore the effect of high dietary cholesterol on the lipid composition; Na+-K+-ATPase activity and ouabain receptor property of the myocardial sarcolemma. Methods: Male New Zealand white rabbits were fed with standard chow or standard chow supplemented with 0.5% (w/w) cholesterol and 10% (w/w) coconut oil to induce hypercholesterolemia. After 8 weeks, the rabbits were sacrificed; a myocardial sarcolemma fraction was then prepared from the left ventricular myocardium and analyzed for lipid composition. Assay of Na+-K+-ATPase activity and 3H-ouabain binding studies were performed in the myocardial sarcolemma from the control and cholesterol-fed rabbits. Results: The cholesterol content, but not the phospholipid content, of the sarcolemma was significantly greater in the cholesterol-fed group, thus, resulting in an increased cholesterol/phospholipid molar ratio in the cholesterol-fed group. In addition, a decrease in Na+-K+-ATPase activity was also found in this group. The decrease in Na+-K+-ATPase activity was selective, since the Mg++-ATPase and 5'-nucleotidase activities remained unchanged. In the 3H-ouabain binding study, a decrease in the number of maximum binding sites, but not the binding affinity, for 3H-ouabain was found in the cholesterol-fed group. Conclusions: High dietary cholesterol induces higher levels of cholesterol not only in the plasma, but also in the myocardial sarcolemma. These changes result in decreased myocardial Na+-K+-ATPase activity mediated by a reduction in the maximum number of binding sites for ouabain but not a change in binding affinity.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00803751
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    Paper (German National Licenses)
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