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  • 1
    ISSN: 1432-0533
    Keywords: Key words Pure autonomic failure ; Lewy bodies ; Autopsy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Pure autonomic failure (PAF; also known as idiopathic orthostatic hypotension or Bradbury-Eggleston syndrome) is an uncommon sporadic disorder, characterized by autonomic failure without other neurological deficits and histopathologically by cell loss in intermediolateral columns and sympathetic ganglia. Few postmortem studies of patients with PAF have been reported in the literature, and none have demonstrated Lewy bodies in distal axons, although this has been described as a feature in Parkinson’s disease with autonomic failure. We report a patient with PAF who had orthostatic hypotension and urinary symptoms for 15 years prior to death at the age of 63 years. Postmortem findings included typical and atypical Lewy bodies in the substantia nigra, locus ceruleus, substantia innominata, and sympathetic ganglia, as well as in autonomic axons in the epicardial fat, autonomic nerve fascicles in periadrenal adipose tissue, and autonomic nerves in the muscularis of the urinary bladder. Sites of autonomic nerve involvement correlated with clinical symptomatology, and thus were a valuable observation in the complete autopsy. Systemic autopsy results should be reviewed carefully in patients with PAF, as Lewy bodies in this disease may be seen in distal axons at a great length from their primary cell bodies.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Pediatric radiology 26 (1996), S. 280-281 
    ISSN: 1432-1998
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract From April 1992 to May 1994, 780 patients aged from 1 day to 8 years were examined. Sedation of these patients was conducted by giving chlorprothixene orally and, in some cases, chloral hydrate had to be added. The patients were monitored with a pulse oxymeter. Investigations could begin after 50–120 min. In 710 patients (91 %) the first attempt to perform the examination was successful; 70 patients required one or two further attempts. Only two of the 780 patients (0.5 %) showed evidence of respiratory depression. The total number of pediatric MRI examinations performed in 1 year is almost 1000. In the hands of an experienced pediatric radiologist these examinations can be performed entirely without anesthesia.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Journal of superconductivity 11 (1998), S. 755-768 
    ISSN: 1572-9605
    Keywords: Optical properties ; electron–phonon interaction ; high-T c superconductors
    Source: Springer Online Journal Archives 1860-2000
    Topics: Electrical Engineering, Measurement and Control Technology , Physics
    Notes: Abstract Observed optical reflectivity in the infrared spectral region is compared with theoretical predictions in a strongly coupled electron–phonon system. Starting from a Fröhlich Hamiltonian, the spectral functions and their temperature dependence are derived. A full analysis including vertex corrections leads to an expression for the optical conductivity σ(ω) that can be formulated in terms of the well-known optical conductivity for a quasi-isotropic system without vertex corrections. A numerical comparison between the full result and the so-called extended Drude formula, its weak coupling expansion, shows little difference over a wide range of coupling constants. Normal-state optical spectra for the high-T c superconductors YBa2Cu3O7 and La2 − x Sr x CuO4 at optimal doping are compared with the results of model calculations. Taking the plasma frequency and ∈∞ from band structure calculations, the model has only one free parameter, the electron–phonon coupling constant λ. In both materials the overall behavior of the reflectivity can be well accounted for over a wide frequency range. Systematic differences exist only in the mid-infrared region. They become more pronounced with increasing frequency, which indicates that a detailed model for the optical response should include temperature-dependent mid-infrared bands.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Journal of low temperature physics 105 (1996), S. 969-974 
    ISSN: 1573-7357
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Some YBCO ceramics have been found to exhibit hysteresis of the current/voltage, I/V, characteristics, which reveals at a certain current If greater than critical current Ic a transition with switch from one branch of the I/V curve to another. In present work, the influence of an electric field at 77 K on hysteresis of I/V curves of ceramic YBCO/Ag and YBCO after hydrogen treatment has been studied. It was established that in strong electric field (120 MV/m) the conductivity increases at current I〉Ic, the field effect being observed only in the upper branch of hysteresis loop. The electric field effect in YBCO after hydrogen treatment is reversible. The observed effects are assumed to be associated with a change of grain boundary weak links from S/I/S-to S/N/S-type in the course of hydrogen treatment or addition of silver into ceramics.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Clinical autonomic research 5 (1995), S. 211-213 
    ISSN: 1619-1560
    Keywords: erythropoietin ; orthostatic hypotension ; autonomic failure ; anemia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Anemia is a common complication of autonomic failure and reduced red blood cell mass may contribute to the orthostatic hypotension of these patients. We investigated whether treatment with recombinant erythropoietin improves anemia and increases blood pressure in patients with primary autonomic failure. Three patients with multiple system atrophy and autonomic failure and one with pure autonomic failure were studied. All patients had normocytic normochromic anemia and low (n = 2) or normal (n = 2) serum levels of erythropoietin. Treatment with erythropoietin, 4000 U subcutaneously biweekly for 6 weeks, increased hematocrit and blood pressure in all patients. Hematocrit increased from 33.9 ± 0.7 to 44.3 ± 1.4%, blood pressure in supine position increased from 150 ± 8/87 ± 8 (systolic/diastolic; mean ± SD) to 166 ± 25/92 ± 12 mmHg, and after 3 min in the head-up tilt position from 86 ± 21/47 ± 15 to 102 ± 23/63 ± 12 mmHg, (p 〈 0.05). All patients reported improvement in orthostatic symptoms and increased tolerance to standing. The study shows that treatment with erythropoietin improves anemia, increases blood pressure and ameliorates orthostatic hypotension in patients with primary autonomic failure.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1432-1955
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Repetitive DNA sequences present in the genome of Dicrocoelium dendriticum were identified by hybridization of genomic DNA that had been digested with different restriction enzymes with 32P-labeled genomic D. dendriticum DNA. DNA fragments containing repetitive sequences were isolated from PstI-digested D.␣dendriticum DNA and were subcloned into a plasmid vector. Plasmids containing repetitive sequences were identified by colony hybridization. One of these plasmids, designated Ddr-IV, was isolated and used as a probe in further studies. Ddr-IV is specific for D. dendriticum since it does not hybridize to DNA isolated from other trematodes. In addition, Ddr-IV was capable of detecting D. dendriticum metacercariae in ants (Formica cunicularia, F. rufibarbis, and Lasius sp.), which act as second intermediate hosts in the parasite's life cycle. Since metacercariae constitute the infectious stage of the parasite for grazing animals, Ddr-IV will provide a useful tool for epidemiology studies of dicrocoeliosis.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 28 (1997), S. 167-175 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Light turbocharger compressor wheels from aluminium and magnesium investment castingWithin the scope of a team work between Kühnle, Kopp & Kausch AG, Volkswagen AG, Sterling International Technologies Ltd. and the Fraunhofer Institute for Strength of Structures under Operational Conditions LBF compressor wheels of aluminium and magnesium investment casting were developed and tested. Strength and fatigue tests, overspeed and field tests as well as metallographic checks were made in addition to the finite element calculations to optimize the stress under centrifugal force in an appropriate way for the materials involved. The results and the knowledge gathered are to clarify whether magnesium alloys are an appropriate replacement for the proven standard aluminium alloy for turbochargers.
    Notes: Im Rahmen einer Zusammenarbeit zwischen der Kühnle, Kopp & Kausch AG, Volkswagen AG, Sterling International Technologies Ltd. und dem Fraunhofer-Institut für Betriebsfestigkeit LBF wurden Verdichterräder aus Aluminium- und Magnesiurn-Feingußlegierungen entwickelt und untersucht. Festigkeits- und Schwingfe-stigkeitsuntersuchungen, Schleuder- und Feldversuche sowie metallographische Untersuchungen wurden von Finite-Element-Berechnungen begleitet, mit denen Spannungsverteilungen am Bauteil optimiert wurden. Anhand der ermittelten Ergebnisse soll geklärt werden, inwieweit Magnesium-Feingußlegierungen die gegenwärtig für Turbolader-Verdichterräder eingesetzten Aluminium-Feingußlegierungen ersetzen können.
    Additional Material: 14 Ill.
    Type of Medium: Electronic Resource
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