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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Manuscripta mathematica 98 (1999), S. 275-293 
    ISSN: 1432-1785
    Keywords: Mathematics Subject Classification (1991):11G25, 14G20, 14H40, 14K15
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Abstract: The structure of component groups of Néron models has been investigated on several occasions. Here we admit non-separably closed residue fields and are interested in the subgroup of rational points or, in other terms, in the subgroup of geometrically connected components of a Néron model. We consider Néron models of abelian varieties and of algebraic tori and give detailed computations in the case of Jacobians of curves.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1550-7408
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: The extent of allelic diversity at the Merozoite Surface Protein-1 locus of Plasmodium falciparum (PfMSP-1) was examined in isolates collected from symptomatic patients living in a mesoendemic area in southern Vietnam. The variable blocks 2, 4 and 10 were typed by polymerase chain reaction and 24 PfMSP-1 gene types were defined as unique combinations of allelic types detected in each variable block. Nineteen PfMSP-1 gene types were identified and 182 parasite populations were fully typed among 102 isolates. Forty-eight (47%) patients harbored more than one typed parasite population, and one patient had at least eight genetically distinct subpopulations. As previously shown in the same endemic area, recombination between blocks 4 and 10 was significantly less frequent than expected from random assortment of allelic types. The distribution of PfMSP-1 gene types, however, did not differ significantly from that observed in isolates collected in the same area 17-24 mo before the present study. Furthermore, the prevalence of the most common gene types and the average number of different gene types harbored by the same host did not decrease with age. This argues against the prominence of frequency-dependent immune selection of PfMSP-1 polymorphisms in this parasite population.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Journal of materials science 8 (1997), S. 543-549 
    ISSN: 1573-4838
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Technology
    Notes: Abstract Natural self-reinforced composite, bamboo, was surface modified by phosphorylation with urea–H3PO4 and NaOH–H3PO4 methods; then precalcification was performed by immersing samples in saturated Ca(OH)2 solution. After that, calcium phosphate can be formed on the surface of bamboo samples in calcification media: simulated body fluid (1.5 SBF) and accelerated calcification solution (ACS). Experimental results reveal that pre-calcification is an inevitable step for the formation of calcium phosphate. The calcium phosphate formed in 1.5 SBF was identified by thin-film X-ray diffraction as apatite which was not well crystallized. Compared with the urea–H3PO4 method, the NaOH–H3PO4 method has the advantages of quicker and continuous apatite formation and stronger adhesive between apatite and bamboo.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1546-1718
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] A total of 52 patients and 12 controls were tested for SMN expression by immunoblot analyses of total proteins extracted from lymphoblastoid cell lines with the polyclonal antibody 95020, the monoclonal antibody 2B1 and an anti-β-tubulin antibody as an internal control. With both SMN-specific ...
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Compositio mathematica 118 (1999), S. 61-102 
    ISSN: 1570-5846
    Keywords: branch locus ; covers ; curves ; discrete valuation ring ; models ; semi-stable ; simultaneous resolution.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Abstract Let K be a discrete valuation field with ring of integers O K .Letf : X ! Y be a finite morphism of curves over K. In this article, we study some possible relationships between the models over O K of X and of Y. Three such relationships are listed below. Consider a Galois cover f : X ! Y of degree prime to the characteristic of the residue field, with branch locus B. We show that if Y has semi-stable reduction over K,thenX achieves semi-stable reduction over some explicit tame extension of K.B/.WhenK is strictly henselian, we determine the minimal extension L=K with the property that X L has semi-stable reduction. Let f : X ! Y be a finite morphism, with g.Y/ 〉 2. We show that if X has a stable model X over O K ,thenY has a stable model Y over O K , and the morphism f extends to a morphism X ! Y. ! Y. Finally, given any finite morphism f : X ! Y, is it possible to choose suitable regular models X and Y of X and Y over O K such that f extends to a finite morphism X ! Y ?As wasshown by Abhyankar, the answer is negative in general. We present counterexamples in rather general situ-ations, with f a cyclic cover of any order 〉 4. On the other hand, we prove, without any hypotheses on the residual characteristic, that this extension problem has a positive solution when f is cyclic of order 2 or 3.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1573-5028
    Keywords: developmental regulation ; elongation factor ; evolution ; gene expression ; rhodophyte, sporophyte
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The life cycle of the red alga Porphyra purpurea alternates between two morphologically distinct phases: a shell-boring, filamentous sporophyte and a free-living, foliose gametophyte. From a subtracted cDNA library enriched for sporophyte-specific sequences, we isolated a cDNA encoding an unusual elongation factor 1α (EF-1α) that is expressed only in the sporophyte. A second EF-1α gene that is expressed equally in the sporophyte and the gametophyte was isolated from a genomic library. These are the only EF-1α genes detectable in P. purpurea. The constitutively expressed gene encodes and EF-1α very similar to those of most eukaryotes. However, the sporophyte-specific EF-1α is one of the most divergent yet described, with nine insertions or deletions ranging in size from 1 to 26 amino acids. This is the first report of a developmental stage-specific EF-1α outside of the animal kingdom and suggests a fundamental role for EF-1α in the developmental process.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Journal of materials science 15 (1996), S. 1882-1885 
    ISSN: 1573-4811
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1022-1352
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: N,N-Diallyl-2-(methoxycarbonyl)allylamine (1a), a trifunctional compound with functional groups of low homopolymerizability, was synthesized and its radical cyclopolymerizability was investigated. Monomer 1a was polymerized to yield high molecular weight polymers with a considerably high polymerization rate; the degree of cyclization (DC) of poly(1a) was about 55%, irrespective of the polymerization conditions, while bifunctional compounds with functional groups of low homopolymerizability have been known to yield highly cyclized polymers. Pendant unsaturations detected in poly(1a) were found to consist almost exclusively of allyl groups. The acryloyl groups and one of the allyl groups of 1a can be regarded as one functional group in a pair with high polymerizability, since N-allyl-N-propyl-2-(methoxycarbonyl)allylamine which has the structure of 1a with one of its allyl groups saturated has been known to yield linear polymers with a DC of 100%. This consideration indicates that 1a has similar cyclopolymerizability to unsymmetrical bifunctional monomers the functional groups of which have high and low homopolymerizability. This is the reason why 1a has low cyclopolymerizability, since such unsymmetrical bifunctional monomers have generally low cyclopolymerizability. The high polymerization tendency of 1a is attributed to the high conjugative nature of the acryloyl group as proven by 13C NMR.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 40 (1998), S. 520-529 
    ISSN: 0021-9304
    Keywords: 3D carbon/carbon composite ; collagen/apatite composite ; coating ; grafting ; phosphorylation ; Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: A three-dimensional carbon/carbon composite (3D C/C) was studied as potential bone-repairing material; its major mechanical properties were found to be closer to those of human bone than other common bone-repairing materials available. In vitro calcification tests revealed that as-received 3D C/C is almost bioinert in simulated body fluid (SBF) over an immersion period of 4 weeks. To improve the bioactivity of 3D C/C, surface modification was accomplished through two practical routes: (1) grafting with polyethylene glycol (PEG) and (2) phosphorylation and precalcification. After grafting with α, ω di(aminopropyl) polyethylene glycol 800 (NH2-PEG-NH2), a continuous layer of calcium phosphate was formed on the surface of 3D C/C in SBF after 4 weeks. Phosphorylated 3D C/C samples have the ability to induce apatite precipitation after precalcification in a saturated Ca(OH)2 solution for 1 week. To speed up the coating process, a calcification solution with collagen was developed in which a collagen/apatite coating layer can be formed on 3D C/C in 9 h in ambient conditions. © 1998 John Wiley & Sons, Inc. J Biomed Mater Res, 40, 520-529, 1998.
    Additional Material: 10 Ill.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 40 (1998), S. 490-497 
    ISSN: 0021-9304
    Keywords: hydroxyapatite ; Polyactive™ ; composites ; interface ; mechanical properties ; surface grafting ; coupling agent ; diisocyanate ; Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: In an effort to make composites from hydroxyapatite and a PEG/PBT copolymer (Polyactive™ 70/30), chemical linkages were introduced between the filler particles and polymer matrix using hexamethylene diisocyanate as a coupling agent. Infrared spectra (IR) and thermal gravimetric analysis (TGA) confirmed the presence of Polyactive™ 70/30 on the surface of HA filler particles. The amount of chemically bound polymer was 4.7 wt.%, as determined by TGA. The mechanical properties of the composites, that is, tensile strength and Young's modulus, were improved significantly by the introduction of a chemical linkage between the filler particles and polymer matrix compared to control composites. This method provides an effective way to introduce chemical linkage between HA filler particles and a polymer matrix. By optimizing the grafting process, a further improvement of the mechanical properties in the composites can be expected. © 1998 John Wiley & Sons, Inc. J Biomed Mater Res, 40, 490-497, 1998.
    Additional Material: 10 Ill.
    Type of Medium: Electronic Resource
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