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  • 1
    Electronic Resource
    Electronic Resource
    Production of insulin-like growth factor I (IGF-I) and IGF-binding proteins by rat intestinal stromal cells in vitro (1998)
    Springer
    Cellular and molecular life sciences 54 (1998), S. 158-166 
    Details
    ISSN: 1420-9071
    Keywords: Key words. Insulin-like growth factors; IGFs; IGFBP; stroma; epithelium; stromal-epithelial interactions.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract. To determine if intestinal stromal cells secrete diffusible factors such as insulin-like growth factors (IGFs) capable of regulating epithelial cell growth in vitro, stromal cells were isolated by enzymatic digestion of rat intestine. Incorporation of [3H]thymidine into DNA and [14C]leucine into protein of IEC-6 cells, a model intestinal epithelial cell line, was significantly increased (two- to threefold) when the IEC-6 cells were co-cultured with stromal cells, relative to IEC-6 cells grown alone. Medium conditioned by stromal cells stimulated DNA synthesis of IEC-6 cells in a dose-dependent manner. Analysis of the conditioned medium revealed that intestinal stromal cells secreted IGF-I, but little IGF-II, in addition to an M r 32,000 IGF-binding protein (IGFBP-2) and an IGFBP having M r∼ 24,000. We conclude that rat intestinal stromal cells secrete one or more diffusible factors, which may include IGF-I and IGFBPs, capable of stimulating proliferation of IEC-6 cells in vitro.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s000180050137
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  • 2
    Electronic Resource
    Electronic Resource
    Transvaginal ultrasound in the management of women with suspected cervical incompetence (1997)
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 104 (1997), S. 0 
    Details
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-0528.1997.tb11474.x
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  • 3
    Electronic Resource
    Electronic Resource
    Polyamine Regulation of N-Methyl-D-Aspartate Receptor Channels (1995)
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Pharmacology 35 (1995), S. 463-482 
    Details
    ISSN: 0362-1642
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Medicine , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1146/annurev.pa.35.040195.002335
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  • 4
    Electronic Resource
    Electronic Resource
    Experimental and theoretical determination of the magnetic dipole transition moment for the Br(4p5)(2P1/2←2P3/2) fine-structure transition and the quantum yield of Br(2P1/2) from the 193 nm photolysis of BrCN (1999)
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 110 (1999), S. 7821-7831 
    Details
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: The integrated-absorption coefficients of several hyperfine lines of the magnetic dipole allowed transition of the bromine atom, Br, center at 3685.2 cm−1 were measured, and a value for the square of the magnetic dipole transition moment of the Br atom was determined. A theoretical calculation for the magnetic dipole transition moment was also carried out using a relativistic ab initio atomic structure formulation. The theoretical value was in excellent agreement with the value predicted assuming pure LS coupling, and in reasonable agreement with experiment. The Br atom was generated in equal concentration with the cyano radical (CN) by the 193 nm photolysis of cyanogen bromine, BrCN. The CN radicals were titrated by the rapid reaction with C3H8 to generate HCN and a small amount of HNC. Both time-resolved and frequency-scanned infrared absorption spectroscopy were used to monitor the Br, HCN, and HNC species. The photolysis of BrCN at 193 nm produced both the ground state Br(2P3/2) and the spin-orbit excited Br(2P1/2) atoms, and the yield for the production of Br(2P1/2) atoms was measured to be 0.31±0.01. The rate constants for the quenching of Br(2P1/2) by BrCN and C3H8 at 293 K were also determined. © 1999 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.478689
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  • 5
    Electronic Resource
    Electronic Resource
    Initial vibrational level distribution of HCN[X˜ 1Σ+(v10v3)] from the CN(X 2Σ+)+H2→HCN+H reaction (1998)
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 109 (1998), S. 4224-4236 
    Details
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: The reaction of the cyano radical (CN) with hydrogen was studied by time-resolved infrared absorption spectroscopy of individual rovibrational states of HCN. The initial vibrational level distribution of HCN(v10v3) was determined by plotting the time dependence of the fractional population of a vibrational level and extrapolating these curves to the origin of time. The experiments were carried out at two temperatures, 293 and 324 K, with similar results. It was estimated that about 50% of the available reaction exothermicity was deposited as vibrational excitation of the HCN product. Surprisingly, the HCN(101) vibrational level received a significant fraction of the observed vibrational population, implying that the CN vibration was not really a spectator bond in the reaction dynamics. Furthermore, the observed HCN(v10v3) vibrations only account for about 27% of the initial HCN population produced in the title reaction. A significant fraction of the product HCN molecules must have been produced with the bending mode excited, likely in combination with the H–C stretch vibrations. © 1998 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.477028
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  • 6
    Electronic Resource
    Electronic Resource
    Experimental measurement of the transition moment for the (2,0) band of the CN A 2Π←X 2Σ+ red system at 789.5 nm (1998)
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 109 (1998), S. 6312-6319 
    Details
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: The square of the electronic–vibrational transition moment for the (2,0) band of the cyano radical (CN), A 2Π←X 2Σ+, red system at 789.5 nm has been determined using a direct time-resolved absorption technique. The line strength of the R1(8.5) transition of 12C14N was measured by comparison to the known line strength of the H12C14N(001)←(000) P(8) infrared υ3 fundamental transition near 3.05 μm. The CN radical was created by pulsed-laser photolysis of cyanogen, (CN)2, in a mixture of H2 and (CN)2 in either Ar or He carrier gas at 293 K. Both CN and HCN were monitored by time-resolved absorption spectroscopy during the same photolysis laser pulse. A simple kinetic model was used to relate the two absorption features to each other. The square of the electronic–vibrational transition moment for the A←X(2,0) band was found to be 7.8±1.0×10−38 esu2 cm2 in good agreement with theoretical calculations based on ab initio quantum chemistry methods. © 1998 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.477273
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  • 7
    Electronic Resource
    Electronic Resource
    The initial vibrational level distribution and relaxation of HCN[X˜ 1Σ+(v1,0,v3)] in the CN(X 2Σ+)+CH4→HCN+CH3 reaction system (1996)
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 105 (1996), S. 4533-4549 
    Details
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: The reaction of the cyano radical (CN) with methane was studied by time-resolved infrared absorption spectroscopy by monitoring individual rovibrational states of the HCN and CH3 products. The initial vibrational level distribution of the bendless vibrational levels of HCN(v1,0,v3) was determined by plotting the time dependence of the fractional population of a vibrational level and extrapolating these curves to the origin of time. About 20% of the HCN products were observed to be initially produced in the HCN(v1,0,v3) vibrational levels, with v1 and v3=0,1,2. The CN radical was created by laser photolysis of three different precursors. Each photolyte provided a different initial vibrational level distribution of CN; however, similar initial HCN(v1,0,v3) vibrational level distributions were obtained independent of the CN radical precursor. This may indicate that the CN radical does not act as a spectator bond during the course of a reactive encounter for this system. The time dependence of the CH3 (00000) ground state was also followed using time-resolved infrared absorption spectroscopy. Preliminary data indicates that a large fraction, if not all, the CH3 radicals are produced in their ground state in the title reaction. © 1996 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.472537
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  • 8
    Electronic Resource
    Electronic Resource
    Direct measurement of the transition dipole moment of the v3 asymmetric C–H stretching vibration of the CH3 radical (1995)
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 103 (1995), S. 2863-2872 
    Details
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: A direct measurement of the transition dipole moment, μ3, of the degenerate v3 in-plane asymmetric C–H stretching vibration of the methyl radical has been made. The measurements were carried out in a flow reactor using laser-photolysis transient infrared absorption spectroscopy. Cyano (CN) radicals (and Cl atoms) were produced by laser photolysis of BrCN (or ClCN) at 193 nm and reacted with methane to give both CH3 and HCN (and HCl). The intensities of 18 rotational lines of the v3 fundamental band were measured relative to the R(8) line of the C–H stretching vibration (v3) of HCN(001←0). The best estimate of the transition dipole moment of the CH3 (00110←0) transition was provided by the measured line intensity for the CH3 (00110←0)rR(3,3) transition and was determined to be μ3=0.0327±0.0021 D. © 1995 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.470499
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  • 9
    Electronic Resource
    Electronic Resource
    Large (50 μm)2 metal–semiconductor–metal photodetectors with 18 GHz bandwidth at 3 V bias; Reduction of hole pileup (1998)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 73 (1998), S. 196-198 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Metal–semiconductor–metal photodetectors were fabricated on an AlGaAs/GaAs/AlGaAs double heterostructure with no graded layers. Devices with photolithographically defined finger spacing and width of 1 μm ("1×1") exhibited a saturation bandwidth of greater than 20 GHz, for bias voltages between 3 and 4 V. We attribute this to minimal hole pileup, and propose a simple model for the energy of hot holes near the band offset at the cathode. Using this model, estimates of the bias required to reduce hole pileup in different material systems were derived. The model shows good agreement with results reported here and elsewhere. © 1998 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.121753
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  • 10
    Electronic Resource
    Electronic Resource
    Contribution by anaesthetists to medical education and training (1995)
    Oxford, UK : Blackwell Publishing Ltd
    Anaesthesia 50 (1995), S. 0 
    Details
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2044.1995.tb06111.x
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