ISSN:
0952-3499
Keywords:
molecular imprinting
;
phage display
;
synthetic enzyme
;
aldol condensation
;
α-chymotrypsin
;
Chemistry
;
Biochemistry and Biotechnology
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Medicine
Notes:
Molecular imprinting and phage display library technologies are rapidly being accepted as useful techniques for the generation of ligand-selective recognition motifs. The use of molecular imprinting to produce a novel type II aldolase mimic selective for the cobalt(II)-mediated aldol condensation of benzophenone and acetaldehyde is reported here. Furthermore, peptide motifs have been identified which are acting as 'affinity ligands' selective for the recognition of the enzyme α-chymotrypsin using phage display techniques.
Additional Material:
7 Ill.
Type of Medium:
Electronic Resource
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