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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Gefässchirurgie 4 (1999), S. 13-19 
    ISSN: 1434-3932
    Keywords: Schlüsselwörter Aszendierende Varikophlebitis ; Klassifikation ; Operationsindikation ; Operationsstrategie ; Key words Ascending varicophlebitis ; Classifica-tion ; Indication for surgery ; Surgical strategy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Abstract Varicophlebitis is the most important acute complication of a varicosed long and/or short saphenous vein. The initial extent and progression of the ascending varicophlebitis can be determined, either by duplex scanning or phlebography. By ascending, an extensive thrombus can enter the deep veins through the respective junctional valve (in the groin or at the knee) or via insufficient perforating veins. In view of pulmonary embolism as a possible complication, a clinically relevant classification of this syndrome appears useful. Stage I includes varicophlebitis without involvement of the respective junctional valve or deep veins. In stage II, the cranial portion of the thrombus has reached the respective junctional valves of the long or short shapenous vein. In stage III, the thrombus has entered the deep veins via these valves. In stage IV, the thrombus has reached the deep system via insufficient perforating veins. Stages I and IV should be treated conservatively, and the varicous veins should not be excised until after the acute phase. Stage II and III should be considered an indication for immediate surgery. The surgical strategy consists of crossectomy, resection of the saphenous vein without stripping, radical excision of all varicous veins and ligature of insufficient perforating veins. In stage III, the thrombectomy of the deep veins using the Fogarthy procedure must be carried out before any other measures are taken. The surgical strategy is similar for the short saphenous vein. In stage I disease, early surgery to alleviate local pain and infection, thus hindering recurrence and decreasing morbidity, should be considered.
    Notes: Zusammenfassung Die Varikophlebitis ist die wichtigste akute Komplikation einer Stammvarikosis vom V.-saphena-magna- und/oder -parva-Typ. Durch Aszension kann es zu einer Migration des Thrombus in das tiefe Venensystem über die Mündungen der Stammvenen in Leiste und Kniekehle oder über insuffiziente Vv. perforantes kommen, wodurch die Komplikation einer Lungenembolie droht. Ausdehnung und Progression einer aszendierenden Varikophlebitis lassen sich mit der Duplexsonographie und/oder Phlebographie diagnostizieren. Eine Klassifikation mit daraus folgenden therapeutischen Konsequenzen erscheint daher sinnvoll. Wir schlagen folgende Einteilung vor: Typ I umfaßt die Varikophlebitis der Stammvenen ohne Beteiligung der Mündungen von V. saphena magna und/oder parva und des tiefen Venensystems. Während der kraniale Thrombusanteil beim Typ II das tiefe Venensystem an der Einmündung der V. saphena magna und/oder parva erreicht, ragt der Thrombus beim Typ III bereits über die Mündung hinaus in das tiefe Venensystem hinein. Beim Typ IV migriert der Thrombus transfaszial über insuffiziente Vv. perforantes in die tiefen Venen. Die Typen I und IV sind die Domäne der primär konservativen Behandlung. Die Varikosis wird bei diesen Fällen erst nach Abklingen der Akutsymptomatik operativ saniert. Für die Typen II und III besteht eine dringliche Operationsindikation. Die Operation beinhaltet die Krossektomie, die Exstirpation der Stammvene über gesonderte Inzisionen, die Exhairese aller varikösen Äste und die Ligatur insuffizienter Vv. perforantes. Beim Typ III besitzt die Thrombektomie über die V.-saphena-magna- und/oder -parva-Mündung Vorrang gegenüber allen anderen Maßnahmen. Zu diskutierten ist der Operationszeitpunkt für den Typ I. Die frühzeitige operative Sanierung der schmerzhaften und langwierigen Erkrankung führt zu einem schnellen Rückgang der lokalen Entzündung und damit zu schnellerer Schmerzfreiheit, zur Verhinderung von Rezidiven mit der Gefahr des Übergangs in progrediente Stadien und zur Verkürzung der Krankheitsdauer.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Clinical rheumatology 17 (1998), S. 346-348 
    ISSN: 1434-9949
    Keywords: Acquired factor XIII deficiency ; Bleeding tendency ; Factor XIII deficiency ; Psoriasis vulgaris ; Wound healing
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Factor XIII (FXIII) links soluble fibrin monomers and collagen fibres to stable fibrin connections. Deficiency of FXIII, caused by dyspoiesis or increased consumption, results in a bleeding tendency and wound healing complications. Although the decrease of FXIII and successful replacement in patients with wound healing complications after surgery have been described by several authors, it is rarely considered that patients with autoimmune diseases, bleeding or healing complications may suffer from FXIII deficiency. We report a patient with severe psoriasis vulgaris generalisata with large, painful erythemas, bleeding tendency, joint contractions and infirmity, whose FXIII activity was 19%. After successful replacement the bleeding tendency vanished, and a marked improvement of skin and joint mobility allowed mobilisation and administration of physical therapy, whereby some independence and mobility were restored to the patient.
    Type of Medium: Electronic Resource
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