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  • 1
    Digitale Medien
    Digitale Medien
    Influences of Watershed Characteristics on Mercury Levels in Wisconsin Rivers (1995)
    s.l. : American Chemical Society
    Environmental science & technology 29 (1995), S. 1867-1875 
    Details
    ISSN: 1520-5851
    Quelle: ACS Legacy Archives
    Thema: Chemie und Pharmazie , Energietechnik
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1021/es00007a023
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  • 2
    Digitale Medien
    Digitale Medien
    Wet oxidation of AlGaAs: the role of hydrogen (1997)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 82 (1997), S. 3134-3136 
    Details
    ISSN: 1089-7550
    Quelle: AIP Digital Archive
    Thema: Physik
    Notizen: Wet oxidation of AlGaAs to form Al2O3 by the reduction of H+ from water to H produces intermediate As2O3. Reduction of As2O3 by H to elemental As enables the escape of arsenic from the oxidized film. Further reduction of As to AsH3 can provide another volatile As species. Formation of intermediate As is problematic for the use of wet oxidation in metal-insulator-semiconductor applications. The kinetic balance between As2O3 formation and As escape can explain the transition between the linear and parabolic time dependence of the wet oxidation of buried AlGaAs layers. The near-total suppression of wet oxidation by O2 is attributed to the suppression of volatile product formation through consumption of atomic hydrogen by reaction with O2 to form H2O in preference to the hydrogen reduction of As2O3. © 1997 American Institute of Physics.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1063/1.366156
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  • 3
    Digitale Medien
    Digitale Medien
    Wet oxidation of AlxGa1−xAs: Temporal evolution of composition and microstructure and the implications for metal-insulator-semiconductor applications (1997)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 70 (1997), S. 2443-2445 
    Details
    ISSN: 1077-3118
    Quelle: AIP Digital Archive
    Thema: Physik
    Notizen: Three important processes dominate the wet thermal oxidation of AlxGa1−xAs on GaAs: (1) oxidation of Al and Ga in the AlxGa1−xAs alloy to form an amorphous oxide, (2) formation and elimination of crystalline and amorphous elemental As and of amorphous As2O3, and (3) crystallization of the amorphous oxide film. Residual As can lead to strong Fermi-level pinning at the oxidized AlGaAs/GaAs interface, up to a 100-fold increase in leakage current, and a 30% increase in the dielectric constant of the oxide layer. Thermodynamically favored interfacial As may impose a fundamental limitation on the use of AlGaAs wet oxidation in metal-insulatorsemiconductor devices in the GaAs material system. © 1997 American Institute of Physics.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1063/1.118897
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  • 4
    Digitale Medien
    Digitale Medien
    Acquired scalp alopecia. Part II: A review (1999)
    Melbourne, Australia : Blackwell Science Pty
    Australasian journal of dermatology 40 (1999), S. 0 
    Details
    ISSN: 1440-0960
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: The neutrophil-associated and infiltrative scarring alopecias are reviewed including folliculitis decalvans, tufted folliculitis, dissecting cellulitis of the scalp, acne keloidalis and follicular degeneration syndrome. The management of acquired scalp alopecia is also reviewed including newer, promising therapies. More specific agents targeting components of the androgen system will make the treatment of androgenetic alopecia more rewarding. Similarly new immunomodulatory therapies show great promise for the lymphocyte-associated alopecias and include a new generation of macrolide immunosuppressives (tacrolimus, SDZ ASM 981, and SDZ 281-240), some of which appear to have good transcutaneous absorption.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1046/j.1440-0960.1999.00323.x
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  • 5
    Digitale Medien
    Digitale Medien
    Lamotrigine-induced toxic epidermal necrolysis treated with intravenous cyclosporin: A discussion of pathogenesis and immunosuppressive management (1996)
    Oxford, UK : Blackwell Publishing Ltd
    Australasian journal of dermatology 37 (1996), S. 0 
    Details
    ISSN: 1440-0960
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: There is growing evidence that the final common pathway of toxic epidermal necrolysis (TEN) is mediated by the cellular immune system which targets drug altered epithelial antigens. This provides a rationale for immunosuppressive therapy. The ideal regimen for quickly turning off epidermal damage in TEN has not yet been determined and the use or benefit of routine immunosuppression remains highly controversial. This article reviews recent advances in the pathogenesis of TEN along with the theoretical benefits of early immunosuppressive treatment in severe cases, specifically utilizing cyclosporin. We describe a 29-year-old woman with TEN due to the anticonvulsant lamotrigine whose successful management included intravenous cyclosporin. The extension of her lesions ceased within 24 hours of initiating cyclosporin (day 7 of her admission). Complications included: scarring alopecia; Enterococcus faecalis septicaemia due to an infected central line; and ulceration and squamous metaplasia of conjunctivae, The potential role of lamotrigine as a cause of TEN is discussed.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1440-0960.1996.tb01057.x
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  • 6
    Digitale Medien
    Digitale Medien
    Naltrexone: A case report of pruritus from an antipruritic (1997)
    Oxford, UK : Blackwell Publishing Ltd
    Australasian journal of dermatology 38 (1997), S. 0 
    Details
    ISSN: 1440-0960
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: Intense, generalized pruritus associated with mycosis fungoides was relieved using subcutaneous naloxone but intensified when changed to the new oral opioid antagonist, naltrexone. Rechallenge again led to worsening in pruritus. This unexpected adverse effect is surprising as naltrexone and naloxone are currently thought to work via similar opioid receptor binding. The worsening of the itch may have been due to adaptation in opioid receptor expression induced by prolonged naloxone therapy, possibly highlighting differential opioid receptor affinity between naltrexone and naloxone, or may have represented an idiosyncratic adverse reaction. Naltrexone and naloxone have been reported to reduce pruritus due to cholestasis, uraemia, morphine epidurals, and possibly atopic dermatitis and urticaria. Naltrexone has the convenience of oral administration and a longer half-life. The role of the opioid system and naltrexone in pruritus is reviewed.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1440-0960.1997.tb01696.x
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  • 7
    Digitale Medien
    Digitale Medien
    Acquired scalp alopecia. Part I: A review (1998)
    Oxford, UK : Blackwell Publishing Ltd
    Australasian journal of dermatology 39 (1998), S. 0 
    Details
    ISSN: 1440-0960
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: In this two-part series we review the acquired scalp alopecias. A broad spectrum of diseases result in alopecia. In this first part we provide a framework for the assessment and diagnosis of scalp hair loss, and begin covering the individual conditions. The non-scarring alopecias covered include effluvium, andro-genetic alopecia, alopecia areata, trichotillomania, and loose anagen syndrome. The scarring alopecias cause permanent pilosebaceous follicle loss; the lymphocyte-associated scarring alopecia described encompasses lichen planopilaris, discoid lupus erythematosus, pseudopelade, and follicular mucinosis. Part II will cover the neutrophil-associaled and infiltrative processes causing scarring alopecia followed by the medical management of alopecia. There is particular reference to newly described conditions and progress in the understanding of older conditions. More recently characterized conditions include the loose anagen syndrome, chronic telogen effluvium, and the frontal fibrosing variant of lichen planopilaris.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1440-0960.1998.tb01476.x
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  • 8
    Digitale Medien
    Digitale Medien
    Successful use of ivermectin in the treatment of endemic scabies in a nursing home (1997)
    Oxford, UK : Blackwell Publishing Ltd
    Australasian journal of dermatology 38 (1997), S. 0 
    Details
    ISSN: 1440-0960
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: Ivermectin, an antiparasitic agent, was successfully used as a sole agent to combat endemic scabies in a closed 33-bed ward of a rural nursing home. Previous topical therapies, including multiple applications of permethrin, -γ-benzene hexachloride, benzyl benzoate and precipitated sulfur in white soft paraffin, had failed. Several patients exhibited hyperkeratotic crusted scabies with head and neck involvement and all residents except one recently arrived resident had evidence of active infestation. All residents were treated with 200 μg/kg of ivermectin and this dose was repeated 2 weeks later in all subjects. Four weeks after the first dose of ivermectin there was no evidence of active scabies and all rashes were totally resolved by 6 weeks. The action of ivermectin, its safety and its indications are discussed.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1440-0960.1997.tb01130.x
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  • 9
    Digitale Medien
    Digitale Medien
    Gene induction/repression response profiling of hepatotoxic agents using cDNA microarrays (1999)
    [s.l.] : Nature America, Inc.
    Nature genetics 23 (1999), S. 80-81 
    Details
    ISSN: 1546-1718
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Medizin
    Notizen: [Auszug] DNA microarray technology is a powerful technique that allows for the simultaneous expression analysis of thousands of genes. In the field of toxicology, microarray analysis can be used to identify individual genes or families of genes regulated during adverse drug reactions. Such information ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/14423
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  • 10
    Digitale Medien
    Digitale Medien
    HIV and AIDS (1995)
    [s.l.] : Nature Publishing Group
    Nature 378 (1995), S. 10-10 
    Details
    ISSN: 1476-4687
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Chemie und Pharmazie , Medizin , Allgemeine Naturwissenschaft , Physik
    Notizen: [Auszug] SIR - The recent study of Darby and col-leagues1 provides a direct link between infection with HIV and increased mortali-ty due to AIDS in British haemophilia patients. Using a different approach, our group has studied the incidence of AIDS in the Sydney blood transfusion popula-tion (all infected ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/378010d0
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