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  • 1
    ISSN: 1279-8517
    Keywords: Non recurrent inferior laryngeal nerve ; Retroesophageal subclavian artery ; Thyroid ; Surgery
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The authors report 17 cases of a right non-recurrent inferior laryngeal n. (NRILN) observed during 15 years of practice of thyroid and parathyroid surgery. In their last two cases, the existence of an aberrant right subclavian a., constantly associated with NRILN, was confirmed by MRI angiography. On the basis of the literature and their own experience, the authors review the incidence of this double anomaly, its embryologic explanation and its anatomic and surgical importance. They stress the diagnostic factors and the therapeutic implications, very different in children and adults, of a particular vascular anomaly whose outcome is little understood.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1279-8517
    Keywords: Non recurrent inferior laryngeal nerve ; Retroesophageal subclavian artery ; Thyroid ; Surgery
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The authors report 17 cases of a right non-recurrent inferior laryngeal n. (NRILN) observed during 15 years of practice of thyroid and parathyroid surgery. In their last two cases, the existence of an aberrant right subclavian a., constantly associated with NRILN, was confirmed by MRI angiography. On the basis of the literature and their own experience, the authors review the incidence of this double anomaly, its embryologic explanation and its anatomic and surgical importance. They stress the diagnostic factors and the therapeutic implications, very different in children and adults, of a particular vascular anomaly whose outcome is little understood.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1279-8517
    Keywords: Non recurrent inferior laryngeal nerve ; Retroesophageal subclavian artery ; Thyroid ; Surgery
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé Les auteurs rapportent 17 cas de non recurrence du nerf laryngé inferieur droit, observés en 15 ans de pratique de la chirurgie thyroidienne et parathyroidienne. Dans les deux dernières observations, l'existence d'une artère subclavière droite aberrante — ou arteria lusoria, constamment associée à l'anomalie nerveuse, a pu être confirmée par une angioIRM. S'appuyant sur la revue de la littérature et sur leur expérience personnelle, les auteurs rappellent la fréquence de cette double anomalie, son explication embryologique et son interêt anatomique et chirurgical. Ils insistent sur les circonstances diagnostiques et les conséquences thérapeutiques, très différentes chez l'enfant et chez l'adulte, d'une anomalie notamment vasculaire dont on connait mal les complications évolutives.
    Notes: Summary The authors report 17 cases of a right non-recurrent inferior laryngeal n. (NRILN) observed during 15 years of practice of thyroid and parathyroid surgery. In their last two cases, the existence of an aberrant right subclavian a., constantly associated with NRILN, was confirmed by MRI angiography. On the basis of the literature and their own experience, the authors review the incidence of this double anomaly, its embryologic explanation and its anatomic and surgical importance. They stress the diagnostic factors and the therapeutic implications, very different in children and adults, of a particular vascular anomaly whose outcome is little understood.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1248-9204
    Keywords: Groin hernia ; Surgical treatment ; Plug repair
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The first results of 140 mesh plug repairs for groin hernias are reported retrospectively. The procedures were performed by 4 surgeons who were totally free to choose mesh plug repair in every individual case. From January 1995 to October 1997 the choice of this operation increased from 20% to 54%. The operation was performed with slight modifications of the original technique as described by Rutkow and Robbins. 84% of the patients were available to follow-up (median 34 months, extremes 3 to 58). Results can be considered as good concerning the recurrence rate (0.9%) but tolerance of the material remains questionable: 7 patients (6.3%) experienced long-lasting pain in the groin leading to plug removal in 2 cases. These data must be considered and need further evaluation.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Journal of inclusion phenomena and macrocyclic chemistry 34 (1999), S. 69-84 
    ISSN: 1573-1111
    Keywords: β-cyclodextrin ; α-aminoacids ; pentapeptides ; inclusion complexes ; host–guest interaction ; molecular simulation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract A computational study of host-guest inclusion complexes between β-cyclodextrin (β-CD) and the 20 natural L-α-aminoacids and some selected pentapeptides was carried out and aimed at understanding the nature of the driving forces and mechanism leading to their formation. Relative complexation energies for the complexes with β-CD were calculated in both cases and the solvation Gibbs free energies were also evaluated for the single L-α-aminoacids. The computed results indicate strong possibilities of formation of inclusion complexes between β-CD and single L-α-aminoacids as well as pentapeptides which have hydrophobic side chains. In addition, noteworthy interactions of the side chain of the pentapeptides with the β-CD were also elucidated. A detailed molecular dynamics calculation of one of the representative pentapeptide/β-CD inclusion complex (β-CD/CH3-Ala-Ala- TYR-Ala-Ala-CH3) in aqueous solution has also been carried out. Molecular dynamics calculations support aspects connected with the formation and description of hydrogen bonds and with the role of dispersion forces in the inclusion complex in water.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1434-9949
    Keywords: Key words:Activity – ANCA – Antiproteinase 3 – Serology – Vasculitis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract: We addressed the clinical significance of antiproteinase 3 (anti-PR3) antibody (Ab) positivity by reviewing the files of 79 patients whose serum contained antineutrophil cytoplasmic antibodies with a cytoplasmic staining pattern (cANCA) and had been tested for anti-PR3 reactivity. Vasculitis was present in most (22/35) cANCA+ PR3+ patients but in only a few (5/44) cANCA+ PR3+ patients, thereby suggesting that anti-PR3 Ab positivity in cANCA+ patients is more indicative of vasculitis than cANCA positivity alone. Noteworthy, one-third of cANCA+ PR3+ patients – those with anti-PR3 Ab titres lower than 100 U/ml – did not suffer from vasculitis. Anti-PR3 reactivity in vasculitis patients was only weakly associated with Wegener’s granulomatosis (WG), as nine out of 22 cANCA+ PR3+ vasculitis patients (41%) did not fulfil the ACR classification criteria for WG. There was no correlation between anti-PR3 Ab titres and disease activity at diagnosis. However, titres measured when patients were in remission were much lower than initial values. Taken together, our results indicate that anti-PR3 Ab positivity should be interpreted in its clinical context.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Computational Chemistry 16 (1995), S. 1449-1458 
    ISSN: 0192-8651
    Keywords: Computational Chemistry and Molecular Modeling ; Biochemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Computer Science
    Notes: We present a formal and numerical comparison between the iterative and matrix-inversion approaches of the polarizable continuum model. The formal analysis shows completely the equivalence of the two approaches. Numerical equivalence is also recovered, introducing in both methods the proper boundary conditions on the apparent charge distribution. © 1995 John Wiley & Sons, Inc.
    Additional Material: 4 Tab.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    International Journal of Quantum Chemistry 56 (1995), S. 465-474 
    ISSN: 0020-7608
    Keywords: Computational Chemistry and Molecular Modeling ; Atomic, Molecular and Optical Physics
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: We present a formulation of the nonequilibrium solvation problem for the polarizable continuum model (PCM) computational scheme. The solvent is represented by a linear and homogeneous dielectric, characterized by a partition of the medium polarization vector P into a slow and a fast component: P = P8 + Pf. The formalism is expressed in terms of the “direct-BEM” PCM procedure, exploiting the stationarity condition of the free-energy functional of the solute-solvent system in a boundary element method (BEM) computational approach. It parallels a preceding version [Aguilar et al., J. Chem. Phys. 98, 7375 (1993)] based on an iterative PCM procedure. The present version is more convenient for the use of the coupled perturbed Hartree-Fock formalism. The application to the evaluation of the frequency-dependent molecular polarizability is presented as an example. © 1995 John Wiley & Sons, Inc.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    International Journal of Quantum Chemistry 60 (1996), S. 297-306 
    ISSN: 0020-7608
    Keywords: Computational Chemistry and Molecular Modeling ; Atomic, Molecular and Optical Physics
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The formulation of the time-dependent Frenkel variational principle for Hamiltonians containing a term depending on the wave function is here considered. Starting from the basic principles, it is shown that it requires the introduction of a related functional, G, which, for the systems we are considering, has the status of a free energy. An explicit use of functional G as starting point to obtain variational wave functions makes it easier to implement computational methods for a variety of physical and chemical problems in solution, the first one among them being the calculation of frequency-dependent nonlinear optical properties of components of the liquid phase. A concise overview of applications of this approach which are presently being worked out in our laboratory is also given. © 1996 John Wiley & Sons, Inc.
    Type of Medium: Electronic Resource
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