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  • Artikel: DFG Deutsche Nationallizenzen  (2)
  • 1990-1994  (2)
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  • Artikel: DFG Deutsche Nationallizenzen  (2)
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  • 1
    ISSN: 1573-4927
    Schlagwort(e): Rh-related gene ; R-C-E-F system ; molecular genetics ; Southern blot ; phylogeny ; sequences
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Chemie und Pharmazie
    Notizen: Abstract As the chimpanzee R-C-E-F blood group system appears to be the chimpanzee counterpart of the human Rhesus (RH) system, we have tried to determine whether chimpanzee Rh-like genes encode R-C-E-F-related proteins. Chimpanzee genomic DNA, digested by any of eight endonucleases and hybridized with three Rh exon-specific probes, exhibits a high degree of polymorphism. Analysis of DNA from unrelated individuals of different R-C-E-F types revealed that the presence of some restriction fragments is correlated with particular R-C-E-F types. The cosegregation of these fragments with R-C-E-F haplotypes was confirmed by family studies. Oligonucleotides complementary to regions flanking human exons were used as PCR primers on chimpanzee DNA; the resulting amplified fragments were identical in size to their human counterparts. Moreover, the nucleotide sequences of the fragments present a high degree of similarity to the corresponding human regions.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Springer
    International journal of anthropology 6 (1991), S. 21-28 
    ISSN: 1824-3096
    Schlagwort(e): Gene frequencies ; bar code ; ethnic origin
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie
    Notizen: Abstract A comparison of erythrocyte markers (ABO, Rh system) gene frequencies was done by bar code diagrams in populations of variable ethnic origin. The results from missions for the development in Far East Asia (China, Indochina, New Guinea) were compared to well known gene frequencies of the populations living in other regions: inhabitants of the islands of the Pacific ocean, Europeans of New Zealand and Western Europe (France), Europeans of North America, Ameridans of Peru and Bolivia, Somalians of Africa. Polymorphism was observed in immense country very peopled, monomorphism was found in small and isolated region but polymorphism existed in tribes living in very isolated islands.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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