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  • Electronic Resource  (3)
  • 1990-1994  (3)
  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Clinical & experimental allergy 21 (1991), S. 0 
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: We have examined the relationship between month of birth and episodes of wheezing, productive cough, eczema and hayfever, and also standardized maximum midexpiratory flow (FEF25–75) in a representative sample of 4549 Australian primary schoolchildren (mean age 10.1 years). Children experiencing frequent wheezing (one or more episodes per month) were more likely to be born in spring and summer (odds ratio =1.6, 95% confidence interval = 1.1–2.4), but this was not seen for less severe disease. No effect of season or birth month was seen for the other illnesses examined or for lung function.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Archives of environmental contamination and toxicology 26 (1994), S. 425-434 
    ISSN: 1432-0703
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Notes: Abstract Whole body and liver analyses indicated that wintering redheads (Aythya americana; n=70) in coastal Louisiana (one site) and Texas (two sites) were relatively free of contamination with common trace elements, organochlorines, and hydrocarbons. Most trace elements, including As, Cr, Hg, Mg, Mn, Ni, Pb, Se, Sr, and Zn, were within background concentrations in livers; levels of B, Cd, Cu, and Fe were elevated in some specimens. Only one organochlorine, DDE, was detected in redhead carcasses, but its concentration was below reported toxic levels in waterfowl. Body burdens of aliphatic and aromatic hydrocarbons were generally low, but levels of pristane, total hydrocarbons, and the ratios of phytane:n-octadecane and pristane:n-heptadecane were indicative of possible chronic exposure to petroleum. Based on brain cholinesterase assays, redheads were not recently exposed to organophosphorous or carbamate pesticides. Of 30 elements or compounds tested for seasonal differences, only Se increased from early to late winter at one of the three sites. Eight of 57 contaminants differed among the three sites; no sex or age differences were found.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1573-0778
    Keywords: cell culture ; kinetics ; Ig promoter/enhancer ; plasmacytoma ; recombinant protein production
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Abstract A model mammalian cell system for the production of recombinant proteins was investigated. Murine myeloma cells which had lost the ability to produce both heavy and light chain immunoglobulin molecules were transfected with a vector containing the immunoglobulin heavy chain promoter and enhancer elements linked to the human growth hormone gene. The growth kinetics of G32, a clonal isolate, were found to be similar to both the parent myeloma and hybridomas. However, production of hGH by G32 was growth associated, rather than as a secondary metabolite as is the case for hybridomas. In addition, G32 produced hGH at molar levels greater than most hybridomas.
    Type of Medium: Electronic Resource
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