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  • 1990-1994  (1)
  • 1985-1989  (1)
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  • 1
    ISSN: 1432-1246
    Schlagwort(e): Biological monitoring ; Excretion rate ; Uptake
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Styrene exposure of 18 workers in fiber-glass reinforced plastic industries was measured for 30-min periods throughout each workday for a week. The styrene uptake was estimated using pulmonary ventilation measurements. All urine voidings were collected separately and the styrene metabolites, mandelic acid (MA) and phenylglyoxylic acid (PGA) were determined. The relationship between both exposure and uptake versus excretion of these metabolites was studied. Styrene metabolite concentrations and excretion rates (with 95% tolerance limits) were calculated to correspond to a constant 8-h exposure at the Swedish exposure limit level (25 ppm) or an uptake of an exposure limit related styrene dose (6.3 mmol). The tightest tolerance limits were obtained for excretion rate of MA + PGA per 24 h. The calculated biological exposure limit was 3.4 (± 0.7) mmol MA + PGA/24 h for a dose of 6.3 mmol styrene.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    ISSN: 1432-1246
    Schlagwort(e): Mandelic acid ; Occupational exposure ; Phenylglyoxylic acid ; Respiratory protective equipment ; Styrene
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary In a plastic boat company we studied workers' attitudes toward wearing respiratory protective equipment and differences in styrene exposure received with and without respirators. The workers studied used either half-facepiece air-purifying or full-face air-supplied respirators as much as possible during the first day of the study. On the second day respirators were used only for short periods or not at all. Individual styrene exposures were measured by personal air sampling in the breathing zone. When using respirators the exposure was measured both inside and outside the respirators. The styrene metabolites mandelic and phenylglyoxylic acids were determined in urine samples collected during the workday. The eleven workers studied used the respirators 52% of the time on the first day and 7% of the time on the second. The reasons for not wearing respirators were that they delayed work, were too tight and uncomfortable, made it difficult to breath, and/or became too warm. The use of respirators during work operations such as spraying, laminating, and painting reduced the styrene exposure by 56%–92% . The excretion rate of mandelic and phenylglyoxylic acids in urine collected at the end of the working day was 30%–99% lower when respirators were worn than when they were not.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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