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  • 1
    Electronic Resource
    Electronic Resource
    Computer searching of infrared spectra using peak location and intensity data (1976)
    s.l. : American Chemical Society
    Analytical chemistry 48 (1976), S. 717-721 
    Details
    ISSN: 1520-6882
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ac60368a027
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Immunotactoid-like endoneurial deposits in a patient with monoclonal gammopathy of undetermined significance and neuropathy (1992)
    Springer
    Acta neuropathologica 84 (1992), S. 484-494 
    Details
    ISSN: 1432-0533
    Keywords: Neuropathy ; Immunotactoid ; Endoneurial deposits ; Monoclonal gammopathy ; Skin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary An 85-year-old man with a 2-year history of progressive lower limb weakness and paresthesia was found to have an IgG kappa monoclonal gammopathy of undetermined significance (mgus). Clinical and electrophysiological studies revealed a severe distal bilateral symmetrical polyneuropathy. a sural nerve biopsy showed extensive nerve fibre loss with the deposition of large amounts of amorphous material throughout the endoneurium. Electron microscopy showed the deposits to be composed of microtubular structures which were located diffusely throughout the endoneurium. The deposits were also located within the lumina of the vasa nervorum, some of which were undergoing disintegration and rupture with release of the proteinaceous material into the endoneurium. The regions of the nerve in which they appeared most numerous showed more severe nerve fibre damage than other areas. These microtubular structures were also observed in disintegrating vessels and adjacent endoneurium. On immunohistochemistry they stained with antibody to IgG. Identical deposits were found in the dermis in which there was a leucocytoclastic vasculitis. Located in linear arrays within the axons of myelinated and unmyelinated fibres were highly organised tubular structures resembling immunotactoids. Identification of immunotactoidlike structures within the nerve is unique and may be another mechanism by which monoclonal proteins can induce nerve fibre injury.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00304467
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  • 3
    Electronic Resource
    Electronic Resource
    Advanced Medical Technology-Social and Ethical Implications (1976)
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Sociology 2 (1976), S. 231-268 
    Details
    ISSN: 0360-0572
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Sociology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1146/annurev.so.02.080176.001311
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  • 4
    Electronic Resource
    Electronic Resource
    Human Ethology (1976)
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Anthropology 5 (1976), S. 265-288 
    Details
    ISSN: 0084-6570
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Ethnic Sciences , Biology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1146/annurev.an.05.100176.001405
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  • 5
    Electronic Resource
    Electronic Resource
    Temperature Dependence of the NO3 Absorption Spectrum (1994)
    s.l. : American Chemical Society
    The @journal of physical chemistry 〈Washington, DC〉 98 (1994), S. 13144-13150 
    Details
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/j100101a009
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  • 6
    Electronic Resource
    Electronic Resource
    Accuracy of methods for estimating the size of Thanatephorus cucumeris populations in soil (1992)
    Oxford, UK : Blackwell Publishing Ltd
    Soil use and management 8 (1992), S. 0 
    Details
    ISSN: 1475-2743
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Geosciences , Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Abstract. The accuracy of assays based on galactosidase and the enzyme-linked immunosorbent assay specific to Thanatephorus cucumeris were compared with techniques based on soil dilution plating and baiting in sterilized field soil. Although soil dilution plating is reasonably quantitative, it requires substantial time, material and labour. Plant baits gave inconsistent results in the estimation of T. cucumeris populations in the soil. Enzyme-linked immunosorbent assay (ELISA) using monoclonal antibodies is suitable for detecting the presence of a range of anastomosis groups (AGs) of 71 cucumeris in soil samples, but more quantitative applications seem to be limited to a very narrow range of concentrations of the fungus (0–10 μg/g). Monoclonal antibody ELISA could be used if the soil samples are routinely further diluted, provided the range of concentrations is uniformly low. An assay of β-galactosidase permits estimation of a more adequate range of concentrations (0–500 μg/g) and may be used in defined experiments using uninoculated soil samples.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1475-2743.1992.tb00887.x
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  • 7
    Electronic Resource
    Electronic Resource
    Allergenicity of the cat flea (Ctenocephalides felis felis) (1993)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical & experimental allergy 23 (1993), S. 0 
    Details
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Adult fleas, spent and unspent culture media were extracted and the radio-atlergosor-bent test (RAST) performed with sera of 48 cat flea skin test-positive individuals from the Tampa Bay area of Florida. Sixteen sera (33.6%) had a positive RAST to the cat flea extract prepared in our laboratory [1.7-11.4% of the total counts (TC) added]. Six of the 16 sera (12.5%) also contained specific IgE to allergens in thespent medium (0.8-3.3% TC). The allergen composition and strength were studied by RAST inhibition of two commercial cat flea extracts and compared with our in-house flea extract. The results demonstrated similar allergen compositions and different potencies. Sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) of the in-house flea extract showed several Coomassie blue-stained bands (10–85 kD). SDS-PAGE immunoblols revealed five IgE-binding bands at 34, 35, 39, 54 and 60 kD. Flea allergens were quantified in eight house dust samples using RAST inhibition assays and expressed as RAST inhibition units; five of these samples contained detectable levels. Cat flea allergens may contribute to the allergenicity of house dust in areas of heavy llea infestation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2222.1993.tb00342.x
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  • 8
    Electronic Resource
    Electronic Resource
    A study of lung-specific, cell-mediated immunity in chronic pulmonary diseases (1977)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical & experimental allergy 7 (1977), S. 0 
    Details
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Lung-specific, cellular hypersensitivity was studied in patients with chronic pulmonary diseases. To do this, a leucocyte migration inhibition assay was performed using patient and control leucocytes incubated in the presence and absence of a soluble lung extract. Control antigens consisted of liver and kidney extracts. The immunological reactivity of these control antigens was tested by measuring migration, subsequent to incubation of leucocytes from patients with hepatic or renal disease with the liver and kidney extracts, respectively. As a second in vitro test of cell-mediated immunity, a lymphocyte cytotoxicity assay was performed, using as target cells normal chromium-labelled human lung cells.Leucocyte migration inhibition was produced by the lung extract in four out of six patients with chronic bronchitis, five out of seven patients with tuberculosis, one out of five patients with sarcoidosis and in the single patient studied with rheumatoid lung disease. Inhibition did not occur with the leucocytes from control subjects. Neither was migration inhibited when leucocytes from the patients with lung disease were incubated with the control antigens. The reactivity of these control antigens was confirmed by the fact that leucocyte inhibition occurred in two out of three patients with hepatic disease, studied using the liver extract, and in two out of three patients with renal disease, studied with the kidney extract. The cytotoxic potential of anti-lung lymphocytes was demonstrated by the fact that significant target cell cytotoxicity occurred using lymphocytes from two out of four patients with chronic bronchitis, four out of five patients with tuberculosis and in two out of four patients with sarcoidosis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2222.1977.tb01484.x
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  • 9
    Electronic Resource
    Electronic Resource
    Cellular immunity to a lung homogenate in asymptomatic cigarette smokers (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical & experimental allergy 8 (1978), S. 0 
    Details
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Leucocyte migration in the presence and absence of a soluble lung homogenate has been studied in a group of asymptomatic cigarette smokers. Results were expressed as migration indices. Controls consisted of age-matched subjects who had never smoked and had no past history of any pulmonary disease. The migration indices, the number of pack-years* smoked and the results of pulmonary function studies were tested for correlation.The mean leucocyte migration index of the test group of sixteen smokers was significantly less than was that of the control group (P 〈 0·001). Inhibition of leucocyte migration in the presence of the lung homogenate was not observed in any of the control subjects. Six of the sixteen asymptomatic cigarette smokers, however, were identified by inhibition of leucocyte migration in the presence of the lung homogenate. The number of pack-years which had been smoked did not correlate with the migration indices (r=−0·06); however, inhibition of leucocyte migration was not observed in subjects who had smoked less than 6 pack-years.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2222.1978.tb00467.x
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  • 10
    Electronic Resource
    Electronic Resource
    Effect of inoculum source on root and tuber infection by potato blemish disease fungi (1992)
    Oxford, UK : Blackwell Publishing Ltd
    Plant pathology 41 (1992), S. 0 
    Details
    ISSN: 1365-3059
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: The incidence of potato pathogens on healthy roots of micropropagated (MP) and seed tuber (ST) plants was examined on successive dates during the growing season in two field experiments. Microplants were grown in a glasshouse for 4–5 weeks in perlite or peal-based substrates, and exposed or not to natural inoculum before planting in the field. The seed tubers originated from stocks of visually clean or moderately blemished tubers and were surface-sterilized or not before planting. Polyscytalum pustulans and Helminthosporium solani only infected roots of ST plants and inoculated MP plants. The incidence of P. pustulans was affected by seed tuber-borne inoculum and, in I year, by the substrate. H. solani was detected infrequently on roots. Rhizoctonia solani was present at low frequencies in most root samples, and more ST than MP plant roots were colonized; there were no substrate effects. In 1 year, increased inoculum levels increased root infection, but only in MP roots. Colletotrichum coccodes occurred at high frequencies and was most common in roots of ST plants. Progeny tubers showed some treatment effects when tested in September and after storage for 6 months, but there were no consistent relationships between root and progeny tuber infection.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-3059.1992.tb02340.x
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