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  • 1990-1994  (5)
  • 1975-1979  (3)
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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 633 (1991), S. 0 
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 633 (1991), S. 0 
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    European journal of neuroscience 2 (1990), S. 0 
    ISSN: 1460-9568
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: We have investigated the influence of platelet-derived growth factor (PDGF) in peripheral nervous system gliogenesis using two types of Schwann cell cultures. Short-term Schwann cell cultures grow very slowly, but when maintained in culture for several months the division rate of some cells increases, and cell lines can be established. We show that Schwann cells in both short- and long-term culture possess PDGF receptors and synthesize DNA in response to PDGF. Competitive binding experiments show that Schwann cells express mainly PDGF β-receptors and respond better to PDGF-BB than to PDGF-AA. Conditioned media from short-and long-term Schwann cell cultures contain PDGF-like mitogenic activity, and anti-PDGF immunoglobin partially inhibits DNA synthesis in long-term Schwann cell cultures. Antibody neutralization experiments and Northern blot analyses both indicate that the predominant PDGF isoform in these cultures is PDGF-BB. PDGF-like activity is also detected in extracts of rat sciatic nerve. Taken together, these results suggest that PDGF-BB may stimulate Schwann cell proliferation in an autocrine manner during normal development.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Graefe's archive for clinical and experimental ophthalmology 208 (1978), S. 217-228 
    ISSN: 1435-702X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Intraokularer Druck, Blutdruck der A. ophthalmica und Episkleralvendruck stiegen beim Übergang vom Sitzen zum Liegen an, wohingegen der Blutdruck in der A. subclavia unverändert blieb oder geringgradig abfiel. Umgekehrt fielen IOD, Ophthalmica- und Subclaviablutdruck beim Wechsel vom Liegen zum Sitzen. Das Ausmaß des Anstiegs bzw. Falls beim Vergleich von jeweils letztem zu jeweils erstem Meßwert betrug für den IOD ca. 20%, für den Ophthalmicamitteldruck ca. 15% und für den Episkleralvenendruck etwa 50%. Sämtliche Freiwilligen-Gruppen zeigten während der ersten 15min ein Abfallen des Subclaviablutdruckes. Der Ophthalmicamitteldruck fiel bei dem Kollektiv, das zuerst saß, während des Sitzens ebenfalls ab, wohingegen er bei den Freiwilligen, die zuerst lagen, in der ersten Körperposition noch anstieg. Der Episkleralvenendruck stieg nach dem Übergang in die liegende Position stärker als der dazugehörige IOD an.
    Notes: Summary The intraocular pressure, the ophthalmic artery pressure, and the episcleral venous pressure increased after change from sitting to recumbent body position, whereas the subclavian artery pressure remained unchanged or decreased slightly. Changing from recumbent to sitting position was followed by a decrease in IOP, ophthalmic pressure, and subclavian artery pressure. Comparing the last measurement in the first position to the first value after change, it was found that the IOP alters by about 20%, the ophthalmic artery pressure by 15%, and the episcleral venous pressure by 50%. In all series a decrease in subclavian artery pressure was observed during the first 15 min. The mean pressure in the ophthalmic artery diminished in the series that changed from sitting to recumbent position, whereas it increased in the other series during the first 15 min. The episcleral venous pressure increased more than the corresponding IOP after changing to the recumbent position.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Insectes sociaux 37 (1990), S. 273-293 
    ISSN: 1420-9098
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Description / Table of Contents: Zusammenfassung Kreuzungsexperimente mit 5 verschiedenen nestkopulierenden Arten der sozialparasitisch lebenden GattungEpimyrma erwiesen sich als außerordentlich erfolgreich. Von 76 kreuzbegatteten Epimyrma-♀ ♀ (verschiedene Kombinationen) produzierten 37 ♀ ♀ 841 hybrid-♀ ♀, 22 hybrid- und 1 Intermorphe. ♀ ♀ der F1-generation wurden mit Hilfe morphologischer und elektrophoretischer Untersuchungen als Hybriden identifiziert. In keiner der Kreuzungen war die Begattungshäufigkeit innerhalb der F1-Generation reduziert. 57 begattete Hybrid-♀ ♀ aus 6 verschiedenen Kreuzungskombinationen produzierten 894 ♀ ♀, 43 und 10 Intermorphe. In der F2-Generation (hier sind die ♂ ♂ Hybriden) ist die Kopulationsaktivität und — häufigkeit stark reduziert. Die untersuchtenEpimyrma-Arten unterscheiden sich in ihrem ♀/ -VerHÄltnis und in der Larvalentwicklung (“rapid brood” / Brut überwintert vor der Verpuppung). Bezüglich der Brutproduktion kreuzbegatteter ♀ ♀ ist ein Einfluß des väterlichen Genoms nur in Einzelfällen nicht auszuschließen. Der Einfluß des Weibchens, bzw. des mütterlichen Genoms, auf die Kastendetermination überwiegt offensichtlich, Veränderungen in dem ♀/ -VerHÄltnis treten daher verstärkt in der Nachkommenschaft der Hybrid-♀ ♀ (F2-Generationen) auf. Das väterliche Genom übt höchstwahrscheinlich keinen Einfluß auf die Larvalentwicklung aus, weder in der F1-Generation noch in der F2-Ceneration.
    Notes: Summary Cross-breeding experiments with 5 intranidal mating species of the social parasitic ant genusEpimyrma turned out to be extraordinarily successful. Out of 76 cross-mated Epimyrma-♀ ♀ (various combinations) 37 ♀ ♀ produced 841 hybrid-♀ ♀, 22 hubrid- and 1 intermorph. ♀ ♀ produced by cross-mated ♀ ♀ were proved as hybrids by morphological and electrophoretical studies. In each cross combination examined within the F1-generation mating activity is not reduced. 57 mated hybrid-♀ ♀ of 6 various crosses produced 894 ♀ ♀, 43 and 10 intermorphs. In the F2-generation (here the ♂ ♂ were hybrids), however, mating activity and mating success strongly declines. ♀/ -ratio and larval development (“rapid brood” / brood hibernates before pupation) of the species examined differ. With regard to the brood production of cross-mated ♀ ♀ only in single cases an influence of the male's genome cannot be excluded. The influence of the ♀, respectively the female's genome, on caste determination obviously dominates. Modifications in the ♀/ -ratrio therefore are more likely in the brood production of hybrid-♀ ♀ (F2-generation). An influence of the male's genome on larval development never was observed, neither in the F1-generation nor in the F2-generation,
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Journal of neurocytology 21 (1992), S. 382-390 
    ISSN: 1573-7381
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Previous studies, showing that cultured rat Schwann cells could be induced to express MHC class II molecules, raised the possibility that Schwann cells in living nerves might, under some conditions, express MHC class II molecules and take part in activation of T lymphocytes. In the present work, the ability of myelin- and non-myelin-forming Schwann cellsin vivo to express MHC class II molecules was investigated. Lymphokines or bacterial antigens were injected into the living sciatic nerve of adult rats. Examination of the nerves three days after injection of interferon-γ or six days after injection of either tumour necrosis factor, antigens from mycobacterium leprae or whole mycobacteria leprae, revealed strong MHC class II immunostaining on some myelin-forming Schwann cells in the vicinity of the injection site. Very few non-myelin-forming cells expressed MHC class II molecules. MHC class II positive mononuclear cells were present in the injected nerves and endothelial cells of capillaries expressed high levels of MHC class II antigens. Crushing the sciatic nerve without injection of factors also induced MHC class II molecules on a few Schwann cells. Thus rat Schwann cells can be induced to express MHC class II moleculesin vivo asin vitro. This strengthens the possibility that in living nerves Schwann cells are able to function as accessory cells in the initiation or augmentation of T cell-mediated immune responses.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1573-7381
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The ultrastructural localization of acetylcholinesterase (AChE) has been studied in the superior cervical ganglion of the rat. Previous descriptions of the general pattern of localization were confirmed, but in addition, AChE reaction product was found within vesicles in preganglionic nerve terminals, and in pinocytotic vesicles and along the basement lamina of capillaries. There was indication of a continuity between AChE reaction product in the cisternae of the rough endoplasmic reticulum of the principal ganglion cells and extracellular reaction product. These observations are discussed with particular reference to AChE as a secretory protein.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Graefe's archive for clinical and experimental ophthalmology 209 (1979), S. 269-278 
    ISSN: 1435-702X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Ein Testplan für klinische Kontrollmessung neuer Tonometertypen wurde ausgearbeitet, urn den Wert von Neuentwicklungen beurteilen zu können. Für die Berechnung statistischer Werte wird ein Computerprogramm im BASIC-System entwickelt. Als Referenzsystem wird die Applanationstonometrie nach Goldmann benützt. Es werden Vorschläge für Höchstwerte der Abweichungen gemacht.
    Notes: Summary Using the applanation tonometry of Goldmann (mechanical-optical applanation principle with constant diameter of the applanation circle) as a reference system, a test plan inclusive of the necessary conditions for the clinical control measurements of new tonometer types and guiding values for judging the usefulness of these new developments are described. For calculation of the statistical values a computer program in BASIC system is specified.
    Type of Medium: Electronic Resource
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