Library

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • Articles: DFG German National Licenses  (5)
  • 1990-1994  (3)
  • 1970-1974  (1)
  • 1945-1949  (1)
Source
  • Articles: DFG German National Licenses  (5)
Material
Years
Year
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 19 (1971), S. 51-69 
    ISSN: 1432-0533
    Keywords: Human Skeletal Muscle ; Autopsy Material ; Biometric Analysis ; Fiber Diameter ; Histograms
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary This study represents an effort to tabulate the normal mean cross-sectional diameters of human striated muscle fibers in post-mortem material ranging in age from five months gestation through senescence. Age, sex, height and weight of the subjects were taken into account. Cases with neuromuscular illnesses or inanition were specifically excluded. All measurements represent mean narrow fiber diameter of celloidin embedded material sampled at the maximum diameter of the muscle belly. Noteworthy findings include a rapid increase in mean narrow diameter of all muscles except gastrocnemius from gestation to the immediate neonatal period. This was followed by a slower gradual increase in fiber diameter until the age of puberty when again a rapid increase was noted in all muscles except the superior rectus. Following puberty, the superior rectus diameter remained relatively constant throughout life. The sternomastoid, deltoid, biceps, sartorius, quadriceps and gastrocnemius continued a gradual steady increase in fiber size until the late third to early fourth decade, thereafter slowly diminishing in size by the ninth decade. Data are presented to show that the fusiform shape of the biceps muscle cannot be entirely attributed to the fusiform shape of the individual fibers. Particular care must be taken in selecting the level of measurement as fiber diameters appear to be significantly larger near the maximum breadth of the muscle bely. Factors are presented for conversion of measurements between various methods of histologic processing. A useful rule is that the ratio of the sizes of fresh-frozen, fixed-frozen, celloidin and paraffin embedded fibers is roughly 10:9:8:7.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 2
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The three-dimensional structure of MerA from Bacillus sp. strain RC607 can be clearly divided into three parts: the two N-terminal regions (residues 1-166), the core (167-616), the equivalent of the glutathione reductase structure, and the C-terminal extension (residues 617-631). This partition is ...
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 3
    facet.materialart.
    Unknown
    Cambridge : Periodicals Archive Online (PAO)
    The Modern language review. 40 (1945) 174 
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 4
    ISSN: 1432-0843
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. A total of 23 women with stage II breast cancer receiving adjuvant cyclophosphamide, methotrexate and 5-fluorouracil had detailed pharmacokinetic monitoring performed on the first and third courses of therapy. The area under the concentration time curve (AUC) of each of these three drugs varied by a factor of 3–4 among patients. No systematic change in pharmacokinetics between the first and third courses was seen for cyclophosphamide, methotrexate or 5-fluorouracil, and the mean AUC for each of the three drugs did not change. However, significant intrapatient variability in drug pharmacokinetics was observed for all three drugs such that the AUC, clearance and half-life in an individual on the third course could not be reliably predicted from data generated on the first course. On the basis of these results, cyclophosphamide, methotrexate, and 5-fluorouracil pharmacokinetic data from one treatment would not be useful information from which the doses for subsequent courses could be determined.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 5
    ISSN: 1432-0843
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A total of 23 women with stage II breast cancer receiving adjuvant cyclophosphamide, methotrexate and 5-fluorouracil had detailed pharmacokinetic monitoring performed on the first and third courses of therapy. The area under the concentration time curve (AUC) of each of these three drugs varied by a factor of 3–4 among patients. No systematic change in pharmacokinetics between the first and third courses was seen for cyclophosphamide, methotrexate or 5-fluorouracil, and the mean AUC for each of the three drugs did not change. However, significant intrapatient variability in drug pharmacokinetics was observed for all three drugs such that the AUC, clearance and half-life in an individual on the third course could not be reliably predicted from data generated on the first course. On the basis of these results, cyclophosphamide, methotrexate, and 5-fluorouracil pharmacokinetic data from one treatment would not be useful information from which the doses for subsequent courses could be determined.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...