Library

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • Articles: DFG German National Licenses  (19)
  • 1990-1994  (15)
  • 1880-1889  (4)
Source
  • Articles: DFG German National Licenses  (19)
Material
Years
Year
  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Molecular microbiology 6 (1992), S. 0 
    ISSN: 1365-2958
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: The entire nucleotide sequence of the Bacillus brevis grsB gene encoding the gramicidin S synthetase 2, which activates and condenses the four amino acids proline, valine, ornithine and leucine has been determined. The gene contains an open reading frame of 13359bp which encodes a protein of 4453 amino acids with a predicted Mr of 510287. The gene is located within the gramicidin S biosynthetic operon, also containing the genes grsT and grsA, whose nucleotide sequences have been determined previously. Within the GrsB amino acid sequence four conserved and repeated domains of about 600 amino acids (45–50% identity) have been identified. The four domains are separated by non-homologous sequences of about 500 amino acids. The domains also share a high degree of similarity (20–70%) with eight peptide synthetases of bacterial and fungal origin as well as with conserved sequences of nine other adenylate-forming enzymes of diverse origin. On the basis of sequence homology and functional similarities, we infer that those enzymes share a common evolutionary origin and present a phylogenetic tree for this superfamily of domain-bearing enzymes.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Molecular microbiology 6 (1992), S. 0 
    ISSN: 1365-2958
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Molecular microbiology 4 (1990), S. 0 
    ISSN: 1365-2958
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: Yersinia and Salmonella harbour plasmids that encode traits important for virulence, enabling both pathogenic genera to survive and grow in cells of the reticulo-endothelial organs during systemic infections. We have detected DNA homology between the Salmonella dublin virulence plasmid pSDL2 and the plasmids of the pathogenic Yersinia species pestis, pseudotuberculosis, and enterocolitica. Three regions of pSDL2 were found to share homology with the virulence plasmid pIB1 of Yersinia pseudotuberculosis. Two separate hybridizing segments mapped within the previously characterized 6.4 kb vir region of pSDL2 in the Sal1 B fragment. The third homologous region involved the regions of plB1, which hybridized to the Sal1 C2 fragment of pSDL2. The virulence plasmid pCD1 from Y. pestis showed similar homology with the three regions of pSDL2. Homologies to the vir and Sal1 C2 regions of pSDL2 were also found on plasmids from Yersinia enterocolitica serotypes 0:9, 0:3 and 0:5, 27. The discovery of separate homologous regions on the virulence plasmids of Salmonella and Yersinia suggests a distant evolutionary relationship.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Molecular microbiology 5 (1991), S. 0 
    ISSN: 1365-2958
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: The virulence properties of various non-typhoid Salmonella serotypes depend on the presence of large plasmids 60–100 kb in size. We have shown previously that the virulence region on the 80 kb plasmid pSDL2 of Salmonella dublinLane maps within a 14kb SalI fragment. In this report we show that an 8.2kb region within this fragment is sufficient to express lethal disease in BALB/c mice. Sequence analysis of this segment revealed six sequential open reading frames designated vsdA–F, which encode putative proteins of 13–65kDa. Deletion analysis and location of Tn5-oriT inserts which abolish virulence suggest that vsdA, vsdC, vsdD and vsdE are essential for virulence expression. Downstream of vsdF we discovered a locus involved in stable plasmid maintenance. Deletion of that region resulted in plasmid multimerization and instability.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 5
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Allergy 47 (1992), S. 0 
    ISSN: 1398-9995
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The daytime sleepiness potentially associated with antihistamines was evaluated by the multiple sleep latency test (MSLT) in a study comparing terfenadine with placebo. According to a double-blind, randomized, cross-over design, 12 healthy men were given either 120 mg terfenadine or placebo once daily in the morning, for 3 consecutive days with a 5-day interval. EEG-polygraphic recordings were made each study day at 9.30 and 11.30 a.m., and 1.30, 3.30, and 5.30 p.m., and the tendency to fall asleep was measured. All mean stage-1 sleep latencies throughout the study failed to show any significant difference between terfenadine and placebo. Accordingly, psychomotor performance assessed by visual and auditory reaction time did not change after treatment. The results of this study confirmed that terfenadine does not induce daytime sleepiness as objectively measured by MSLT.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Helgoland marine research 44 (1990), S. 295-327 
    ISSN: 1438-3888
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract During spring 1986 and winter 1987, zooplankton samples were collected over the entire North Sea by means of a multi-closing net-system. Before taxonomic treatment, wet weight estimates and carbon content conversions were carried out. From this data set, 4 962 522 tons zooplankton biomass (dry weight) were estimated for the whole North Sea during the spring survey. High biomasses (more than 100 mg C/m3) were located in areas between the Orkneys and the Shetlands, off the mouth of the Firth of Forth, the Channel and the river Rhine. Considerable zooplankton biomass was also found parallel to the Danish west coast. Furthermore, a narrow tongue of high biomass (partly greater than 200 mg C/m3) intruded from the north, between 1 °E and 4 °E, into the northern North Sea, turning to the east at 56°N, and continuing into deeper water layers to form a left turning “helix” of high biomass in the central part of the North Sea. During the winter survey the carbon content of the zooplankton stock was a factor 10 lower than in summer. Altogether, 519340 tons of zooplankton biomass (dry weight) were estimated in winter. Centres of relatively high biomass were located off the mouth of the rivers Rhine, Weser and Elbe and off the British east coast moving in a cyclic way across the Dogger Bank into the central North Sea. A further maximum of zooplankton abundance was found in the Skagerrak region. However, an intrusion of zooplankton from the shelf edge into the North Sea was not observed in winter. A qualitative analysis of species composition showed that small copepods dominated the zooplankton in the southern and eastern North Sea. The “eddy” of high biomass in the northern North Sea observed in spring, however, was mostly shaped by the large copepodCalanus finmarchicus (70–90%). The distribution of zooplankton biomass in the North Sea is discussed in relation to the hydrographic conditions and to the biology of the dominant species.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Helgoland marine research 46 (1992), S. 69-91 
    ISSN: 1438-3888
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract During a North Sea survey in late spring 1986, zooplankton biomass (g dry weight/m2) as well as pollutant concentrations in zooplankton (ng/g dry weight) were determined at 127 stations. On the basis of these data, the load of several cyclic organochlorines in zooplankton (ng/m2) was estimated. It appeared that the highest loads of these pollutants were incorporated in the large zooplankton stocks of the northern and central North Sea, north of 56°N, whereas the highest concentrations were found in zooplankton of the southern North Sea. An explanation for the accumulation of pollutants in sediments as well as in benthos organisms of the central and northern North Sea as found by several authors is discussed in connection with the assumption of a considerably high vertical flux of organic material in these areas. The calculation of total zooplankton content in the North Sea during the late spring survey amounted to about 5 million tons dry weight. This biomass was estimated to contain about 2.6 t PCBs, 19.3 kg p,p′-DDE, 12 kg τ-HCH, 6.4 kg HCB und 5.6 kg α-HCH. These results agree with those on other compartments of the North Sea ecosystem (benthos, fish) found in recent literature. The estimated annual turnover of PCBs in zooplankton (15.2 t) is of the same order of magnitude as the estimated amount transported yearly into the North Sea by rivers and the atmosphere (6–13 t).
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 8
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 38-41 (Jan. 1991), p. 775-778 
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 9
    facet.materialart.
    Unknown
    Berlin : Periodicals Archive Online (PAO)
    Orientalistische Literaturzeitung. 85:5 (1990:Sept./Okt.) 530 
    ISSN: 0030-5383
    Topics: Linguistics and Literary Studies , Ethnic Sciences , History
    Notes: Besprechungen
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 10
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 83-87 (Jan. 1992), p. 563-568 
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...