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  • 1
    Digitale Medien
    Digitale Medien
    Development of an invasive macroprolactinoma: a possible consequence of prolonged oestrogen replacement. Case report (1990)
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 97 (1990), S. 0 
    Details
    ISSN: 1471-0528
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1471-0528.1990.tb01733.x
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  • 2
    Digitale Medien
    Digitale Medien
    H− ion source activities at DESY : Proceedings of fifth international conference on ion sources (1994)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 65 (1994), S. 1237-1239 
    Details
    ISSN: 1089-7623
    Quelle: AIP Digital Archive
    Thema: Physik , Elektrotechnik, Elektronik, Nachrichtentechnik
    Notizen: The H− source for HERA is based on the design of that at FNAL. It was modified according to the Deutsches Elektronen-Synchrotron requirements. There is only one H− source connected to the H− LINAC. It must run for long uninterrupted periods with a low duty factor and a high reliability. The measured cesium distribution showed that it is necessary to keep the cold box as a barrier. The operation of the cold box was improved with a new type of high voltage insulator and a special protection against condensation at the feedthrough for high voltage and −30 °C freon. The bending magnet of the cold box will be further improved by using a permanent magnet instead of the electromagnet. A unit was designed that includes all the essential elements which are under vacuum. It can be replaced in minutes and contains a newly designed H2 piezovalve and a remodeled magnetron. The cathode of the magnetron can be heated. It is now possible to run at a low repetition rate of 1/4 Hz and thus reduce Cs and H2 consumption.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1063/1.1145019
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  • 3
    Digitale Medien
    Digitale Medien
    An electronic pepper pot : Proceedings of 5th international conference on ion sources (1994)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 65 (1994), S. 1459-1461 
    Details
    ISSN: 1089-7623
    Quelle: AIP Digital Archive
    Thema: Physik , Elektrotechnik, Elektronik, Nachrichtentechnik
    Notizen: An electronic pepper pot has been developed at DESY for analyzing the H− beam. It consists of a number of slits in front of a harp with a high wire density. Multiplexing of the harp signals is done in the vacuum. The number of slits and the distance between the harp and the slits can be varied according to the beam parameters. The first version consists of a harp with 484 wires which are 0.1 mm wide with a spacing of 0.1 mm. They are printed on a board. The storage and readout is done using three chips in the vacuum. External transfer of the analog signals is done with a few lines. One may measure the current distribution and the emittance within one shot of the beam and is free to choose the time for the sample. This is of special interest for sources with a low repetition rate such as the HERA H− source. The present arrangement is only a first step. Further designs are discussed.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1063/1.1144945
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  • 4
    Digitale Medien
    Digitale Medien
    The 50 MeV H− linear accelerator for HERA:LINAC3 collaboration (1991)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 62 (1991), S. 867-873 
    Details
    ISSN: 1089-7623
    Quelle: AIP Digital Archive
    Thema: Physik , Elektrotechnik, Elektronik, Nachrichtentechnik
    Notizen: The components of the first 50 MeV accelerator in the chain of injectors to the 820 GeV HERA proton ring are described including the high energy transport line. An H− beam originates in the cesium loaded magnetron source, is preaccelerated by a radio frequency quadrupole to 750 keV, raised to 50 MeV energy in three rf resonators, and is analyzed in the transport line. The H− ions are converted to protons by stripping, when the beam is injected over several turns into the synchrotron DESY3.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1063/1.1142023
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  • 5
    Digitale Medien
    Digitale Medien
    Glial Ion Transport and Volume Control (1991)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 633 (1991), S. 0 
    Details
    ISSN: 1749-6632
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Allgemeine Naturwissenschaft
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1749-6632.1991.tb15622.x
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  • 6
    Digitale Medien
    Digitale Medien
    Human Blood Dendritic Cells Exhibit a Distinct T-Cell-Stimulating Mechanism and Differentiation Pattern (1992)
    Oxford, UK : Blackwell Publishing Ltd
    Scandinavian journal of immunology 36 (1992), S. 0 
    Details
    ISSN: 1365-3083
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: In this study, the mechanisms underlying stimulation of T-cell proliferation by human blood dendritic cells (BDC) and their differentiation have been defined with a panel of monoclonal antibodies (MoAbs)- It was found that the MoAbs against LFA-I (CDlla), CD11c. LFA-3 (CD58), ICAM-1 (CD54) or HLA-DR could significantly suppress T-cell proliferation in an allogeneic mixed lymphocyte reaction (P〈0.05), while being unable to inhibit clustering of BDC with T cells. Addition of anti-CD18 or CD45 MoAbs increased the size of clusters after 18 h of culture, but had no effect on the proliferation of T cells (P〈0.05). The suppressive effect of the MoAbs may be viewed not as an inhibition of contact between BDC and T cells, but rather as a blocking of co-stimulatory signals for T-cell activation, which are mediated by interaction of the adhesion molecules. After depleting the BDC preparations of monocytes. we used a double staining in FACS analysis to demonstrate that BDC do not express specific T (CD3), B (CD20 and CD2l)and myeloid cell markers (CDl1b, CDl3 and CD14), but abundant class II antigens. This pattern remained unaltered after 8 days of culture in the presence of 100 U/ml GM-CSF, although a threefold increase of HLA-DQ and ICAM-1 molecules on the cultured cells was observed.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-3083.1992.tb03129.x
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  • 7
    Digitale Medien
    Digitale Medien
    1,25-Dihydroxyvitamin D3 Exerts Opposing Effects to IL-4 on MHC Class-II Antigen Expression, Accessory Activity, and Phagocytosis of Human Monocytes (1993)
    Oxford, UK : Blackwell Publishing Ltd
    Scandinavian journal of immunology 38 (1993), S. 0 
    Details
    ISSN: 1365-3083
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: To investigate the differentiation and activation of monocytes, the combined effects of 1,25-dihydroxyvitamin D3 (D3) and IL-4 on human blood monocytes were examined with respect to expression of MHC class-II antigens, accessory activity, and phagocytic capacity. IL-4 was reported lo upregulate the expression of MHC class-II antigens and accessory activity of monocytes. The experiments described here demonstrate that D3 inhibits the expression of all three subtypes of MHC class-II antigens (HLA-DR, -DP and -DQ) as well as the accessory activity of monocytes. both in a dose- and time-dependent manner. However, D3 enhances the immunoglobulin- and complement-dependent phagocytosis by monocytes in a dose- and time-dependent manner. When monocytes are treated with both IL-4 and D3, the effects of D3 are reverted by IL-4. suggesting that IL-4 induces the development of monocytes into accessory cells, whereas D3 stimulates differentiation of monocytes into classical macrophages. These findings provide further evidence for the contention that, depending on defined stimuli, monocytes may develop either into accessory cells or into classical macrophages.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-3083.1993.tb03237.x
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  • 8
    Digitale Medien
    Digitale Medien
    Getting the Most from Automatic Control (1941)
    s.l. : American Chemical Society
    Industrial & engineering chemistry 33 (1941), S. 1095-1103 
    Details
    ISSN: 1520-5045
    Quelle: ACS Legacy Archives
    Thema: Chemie und Pharmazie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1021/ie50381a003
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  • 9
    Digitale Medien
    Digitale Medien
    Water Metabolism (1942)
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Physiology 4 (1942), S. 89-114 
    Details
    ISSN: 0066-4278
    Quelle: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Thema: Medizin , Biologie
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1146/annurev.ph.04.030142.000513
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  • 10
    Digitale Medien
    Digitale Medien
    Further studies on Pseudomonas aeruginosa LasA: analysis of specificity (1992)
    Oxford, UK : Blackwell Publishing Ltd
    Molecular microbiology 6 (1992), S. 0 
    Details
    ISSN: 1365-2958
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Full elastolytic activity in Pseudomonas aeruginosa is a result of the combined activities of elastase, alkaline proteinase, and the lasA gene product, LasA. The results of this study demonstrate that an active fragment of the LasA protein which is isolated from the culture supernatant fraction is capable of degrading elastin in the absence of elastase, thus showing that LasA is a second elastase produced by this organism. In addition, it is shown that LasA-mediated enhancement of elastotysis results from the separate activities of LasA and elastase upon elastin. The LasA protein does not affect the secretion or activation of a proelastase as previously proposed in other studies. Furthermore, LasA has specific proteolytic capability, as demonstrated by its ability to cleave β-casein. Preliminary analysis of β-casein cleavage in the presence of various protease inhibitors suggests that LasA may be classified as a modified serine protease.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2958.1992.tb01554.x
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