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Digitale Medien

Cell specific DNA-labelling in the repairing blood-brain barrier of the insect Periplaneta americana (1992)

Swales, L. S. ; Howes, E. A. ; Smith, P. J. S.

Springer

Cell & tissue research 267 (1992), S. 535-543

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Details

ISSN: 1432-0878

Schlagwort(e): Blood-brain barrier ; Neural regeneration ; BUdR ; Glia ; Cell proliferation ; Periplaneta americana (Insecta)

Quelle: Springer Online Journal Archives 1860-2000

Thema: Biologie , Medizin

Notizen: Summary This study uses a recently developed technique for preserving the ultrastructure of cells in the insect CNS during immunohistochemical processing for 5-bromo-2-deoxyuridine incorporation into newly synthesised DNA. The results allow us to identify the proliferating cell calsses in the regenerating blood-brain barrier. High resistance barrier cells do not label with the antibody but sheath cells clearly do. Intermediate cell types appearing during repair are identified. It is hypothesised that these cells generate matrix molecules for neural lamella repair and may represent transitional forms as invasive blood cells transdifferentiate into functional sheath cells.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF00319376

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