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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    European journal of neuroscience 6 (1994), S. 0 
    ISSN: 1460-9568
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: A new mutant rat strain with movement disorders has arisen spontaneously in a closed colony of Albino–Swiss rats at the Department of Anatomy, Glasgow University. The animals possess a progressive locomotor disorder which is first apparent at around post-natal day 10. We here report that tyrosine hydroxylase immunocytochemistry demonstrates that these mutants have profound depletions in dopaminergic systems in the substantia nigra and corresponding areas of neostriatum.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    European journal of neuroscience 2 (1990), S. 0 
    ISSN: 1460-9568
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The autoradiographic localization of radiolabelled taurine taken up in the rat substantia nigra in vivo together with conditions of release of the [3H]taurine taken up into brain slices were studied to determine whether they are consistent with the hypothesis that taurine may act as a neurotransmitter in the striatonigral pathway.At the light microscopic level the main cellular elements that became radiolabelled following the injection of [3H]taurine into the substantia nigra could be identified as glial cells. Electron microscope autoradiography confirmed that a subpopulation of glial cells including astrocytes, pericytes, and oligodendrocytes were radiolabelled and that neuronal perikarya were not radiolabelled. In addition, axonal elements including both terminal and preterminal boutons were found to have silver grains overlying them and were thus considered to be radiolabelled. This was supported by a quantitative analysis of the distribution of the silver grains; whereas glial elements had a significantly higher number of grains associated with them than with any other structure, axonal elements had a significantly greater number of grains than dendritic structures.Release of the preloaded [3H]taurine from superfused slices of substantia nigra occurred in response to veratridine, was calcium-dependent and was sensitive to inhibition by high magnesium concentrations or tetrodotoxin. Following the destruction of neurons in the striatum by ibotenic acid injections, although the weight of the ipsilateral substantia nigra was reduced, the uptake of [3H]taurine was not altered. In contrast to this, the veratridine-stimulated release was markedly attenuated, implying that the destruction of striatal neurons causes the loss of sites in the substantia nigra from which exogenous taurine is released.These results add further support to previous suggestions that taurine might act as a neurotransmitter or neuromodulator in the striatonigral pathway.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Plant pathology 42 (1993), S. 0 
    ISSN: 1365-3059
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Variation for virulence was investigated in two populations of Erysiphe fischeri, the cause of powdery mildew of the common annual weed Senecio vulgaris (groundsel). Infection types were recorded on detached leaf segments from 50 inbred lines of S. vulgaris following inoculation with 24 single-conidial-chain isolates of E. fischeri (12 each from two UK sites; one, at Glasgow, located about 480 km north of the other, at Wellesbourne). Mean infection types for each isolate/line combination were categorized by applying several upper limits below which combinations were considered to be incompatible. Regardless of the limit applied, numerous specific virulence and resistance phenotypes could be discriminated. Virulence phenotypes were complex and all isolates were capable of colonizing and reproducing on the majority of groundsel lines. However, all isolates were completely avirulent (no reproduction) on at least one groundsel line, so no isolate was universally virulent. Plants of several groundsel lines exhibiting different resistance phenotypes were exposed to natural infection at Wellesbourne to act as mildew traps, to examine the virulence characteristics of the pathogen population. Common components of the fungus population colonized groundsel lines exhibiting resistance to only a few or none of the single-conidial-chain isolates. Rarer components of the pathogen population colonized groundsel lines with resistance to the majority or all of the isolates previously tested. These latter components of the fungus population also detected resistance in groundsel lines previously recorded as susceptible to all isolates.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Plant pathology 42 (1993), S. 0 
    ISSN: 1365-3059
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: The frequency and distribution of different specific phenotypes for resistance to Erysiphe fischeri was studied in two populations of the annual weed Senecio vulgaris (groundsel) one located in Glasgow, Scotland the other located about 480 km south at Wellesbourne, England. Progeny of individual plants from the two host populations were tested for their response to up to 10 different isolates of E. fischeri, five from each location; each isolate had a different specific virulence phenotype. Most plants in each sample were susceptible to all 10 isolates. The proportion of plants whose progeny were resistant to a particular isolate ranged from 1% to 10% with the exception of resistance to one isolate that occurred with a frequency of 37% at Wellesbourne. Overall, resistance to one or more of the 10 isolates appeared to be more common in the plant population sampled at Wellesbourne than at Glasgow. Of the total number of groundsel line/isolate combinations tested, 10% involving Wellesbourne plants and 2% involving Glasgow plants were incompatible, i.e. resistant/avirulent. Both groundsel populations tended to be dominated by one or two resistance phenotypes but they were nevertheless highly heterogeneous when less frequent resistance phenotypes were considered. This was particularly evident at Wellesbourne where 10 different resistance phenotypes were recorded amongst a total of 75 plants growing within an area of 1 m2.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Plant pathology 42 (1993), S. 0 
    ISSN: 1365-3059
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: The reactions of 20 inbred lines of Senecio vulgaris (groundsel) to inoculation with up to 10 isolates of Erysiphe fischeri (powdery mildew) were investigated in a number of repeat experiments. There was considerable variation among isolate/plant line reaction phenotypes with examples of both isolate-specific complete resistance and isolate-specific partial resistance. Some plant lines possessed high levels of partial resistance to all isolates tested. Incubation temperature and plant age influenced the infection types of some isolate/plant line combinations. In this pathosystem, complete and partial resistance, together with age-dependent and temperature-dependent resistance, appear to have evolved to facilitate a defence strategy based on a complex mosaic of interacting factors.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 73 (1993), S. 3276-3283 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The effects of substrate preparation on the structure and orientation of MgO films grown on (001) GaAs using pulsed laser deposition has been investigated. Textured MgO films displaying a (111)MgO(parallel)(001)GaAs orientation relation with x-ray rocking curve full width at half maximum (FWHM) values as low as 1.8° were obtained in cases where the native GaAs surface oxide was only partially desorbed prior to growth. Reflection high-energy electron diffraction, transmission electron microscopy (TEM), and x-ray pole figure analysis of these films reveals a preferential orientation within the plane of the substrate: [11¯0]MgO(parallel)[11¯0]GaAs and [112¯]MgO(parallel)[110]GaAs. An interfacial layer (∼5 nm thick) was observed in high resolution TEM analysis, and was attributed to a remnant native GaAs oxide layer. Complete desorption of the native GaAs oxide at ∼600 °C in vacuum prior to MgO growth led to significant surface roughening due to Langmuir evaporation, and resulted in randomly oriented polycrystalline MgO films. Growth of MgO on Sb-passivated GaAs substrates, which provided smooth, reconstructed surfaces when heated to 350 °C in vacuum, resulted in cube-on-cube oriented films [i.e., (001)MgO(parallel)(001)GaAs,[100]MgO(parallel)[100]GaAs] with x-ray rocking curve FWHM values as low as 0.47°. TEM analysis of the cube-on-cube oriented films revealed evidence of localized strain fields at the MgO/GaAs interface, indicating the presence of misfit dislocations in the MgO layer.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 73 (1993), S. 7261-7267 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The crystallography and microstructure of an antiferroelectric ceramic of approximate composition Pb0.97La0.02(Zr0.65Sn0.25Ti0.10)O3 have been examined. Transmission electron microscopy (TEM), x-ray, and neutron powder studies were carried out. The cell is metrically tetragonal with a c/a ratio of 0.993 when indexed to the parent cubic perovskite cell. The structure exhibits both a commensurate supercell, believed to be associated with oxygen octahedra distortions, and an incommensurate modulation. The different crystallographic variants of the tetragonal antiferroelectric phase gave rise to a hierarchy of domain structures. Charging of TEM specimens having an incomplete conductive coating caused domain migration.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 68 (1990), S. 6520-6522 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Gold evaporated on air-cleaved (00.1) graphite was observed by scanning tunneling microscopy. Most individual gold islands were not stable during scanning; some islands even appeared to translate. These observations suggest that the interaction between the gold islands and the scanning tunneling microscope tip is stronger than that between the gold and the air-cleaved graphite substrate. Some gold islands were observed to be stable. It was deduced that stable islands at steps were located on the upper layer rather than on the lower layer. It is also deduced that the alignment of the elongated gold grains in the continuous film may be related to cleavage steps.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 61 (1992), S. 351-353 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Superconducting thin films of the two Cu-layer phase in the Pb-doped Bi-Sr-Ca-Cu-O system have been fabricated on {100} LaAlO3 single crystals by the metalorganic deposition from ethyl hexanoate precursors. Thin films given heat treatments in air at 850–860 °C had resistive transitions with a Tc of 86–89 K. The zero-field transport critical current densities were in the range of 2–4×105 A/cm−2 at 77 K and 106 A cm−2 at 45 K in 200–300-nm-thick films. In contrast to c-axis oriented films grown on {100} MgO, x-ray pole figures show that the films grown on {100} LaAlO3 are epitaxial, a result confirmed by electron channeling patterns.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 62 (1993), S. 3028-3030 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The evolution of phases leading to the formation of epitaxial films of nominal composition Tl2Ba2CaCu2O8 on (100) LaAlO3 by post-deposition annealing of amorphous precursor films has been investigated by examining interrupted heat-treatment samples using analytical microscopy and x-ray diffraction. The superconductor, with a composition of Tl1.8Ba2Ca0.94Cu2.6Ox, forms from a melt, which itself formed from intermediary crystalline phases during the continual loss of Tl2O. It is concluded that Tl1.8Ba2Ca0.94Cu2.6Ox, Cu2O, and Tl3Ca5Ox are in subsolidus equilibrium and that a melt phase exists between at least 780 and 860 °C under reducing conditions controlled by the Tl2O vapor.
    Type of Medium: Electronic Resource
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